Africa Fernandez-L
Africa Fernandez-L
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Subgroup-specific structural variation across 1,000 medulloblastoma genomes
PA Northcott, DJH Shih, J Peacock, L Garzia, AS Morrissy, T Zichner, ...
Nature 488 (7409), 49-56, 2012
YAP1 is amplified and up-regulated in hedgehog-associated medulloblastomas and mediates Sonic hedgehog-driven neural precursor proliferation
A Fernandez-L, PA Northcott, J Dalton, C Fraga, D Ellison, S Angers, ...
Genes & development 23 (23), 2729-2741, 2009
The miR-17/92 polycistron is up-regulated in sonic hedgehog–driven medulloblastomas and induced by N-myc in sonic hedgehog–treated cerebellar neural precursors
PA Northcott, A Fernandez-L, JP Hagan, DW Ellison, W Grajkowska, ...
Cancer research 69 (8), 3249-3255, 2009
Characterization of a new subpopulation of mouse CD8alpha+ B220+ dendritic cells endowed with type 1 interferon production capacity and tolerogenic potential.
P Martín, GM Del Hoyo, F Anjuère, CF Arias, HH Vargas, A Fernández-L, ...
Blood 100 (2), 383, 2002
Hereditary hemorrhagic telangiectasia, a vascular dysplasia affecting the TGF-β signaling pathway
A Fernández-L, F Sanz-Rodriguez, FJ Blanco, C Bernabéu, LM Botella
Clinical medicine & research 4 (1), 66-78, 2006
Oncogenic YAP promotes radioresistance and genomic instability in medulloblastoma through IGF2-mediated Akt activation
A Fernandez-L, M Squatrito, P Northcott, A Awan, EC Holland, MD Taylor, ...
Oncogene 31 (15), 1923-1937, 2012
Blood outgrowth endothelial cells from Hereditary Haemorrhagic Telangiectasia patients reveal abnormalities compatible with vascular lesions
A Fernandez-L, F Sanz-Rodriguez, R Zarrabeitia, A Pérez-Molino, ...
Cardiovascular research 68 (2), 235-248, 2005
Therapeutic action of tranexamic acid in hereditary haemorrhagic telangiectasia (HHT): regulation of ALK-1/endoglin pathway in endothelial cells
A Fernandez-L, EM Garrido-Martin, F Sanz-Rodriguez, JR Ramirez, ...
Thrombosis and haemostasis 97 (02), 254-262, 2007
Mutation study of Spanish patients with hereditary hemorrhagic telangiectasia and expression analysis of Endoglin and ALK1
A Fernandez‐L, F Sanz‐Rodriguez, R Zarrabeitia, A Perez‐Molino, ...
Human Mutation 27 (3), 295-295, 2006
Insulin receptor substrate 1 is an effector of sonic hedgehog mitogenic signaling in cerebellar neural precursors
SR Parathath, LA Mainwaring, A Fernandez-L, DO Campbell, AM Kenney
Development 135 (19), 3291-3300, 2008
Gene expression fingerprinting for human hereditary hemorrhagic telangiectasia
A Fernandez-Lopez, EM Garrido-Martin, F Sanz-Rodriguez, M Pericacho, ...
Human molecular genetics 16 (13), 1515-1533, 2007
Mutation analysis in Spanish patients with hereditary hemorrhagic telangiectasia: deficient endoglin up-regulation in activated monocytes
F Sanz-Rodriguez, A Fernandez-L, R Zarrabeitia, A Perez-Molino, ...
Clinical chemistry 50 (11), 2003-2011, 2004
TGF-β regulates the expression of transcription factor KLF6 and its splice variants and promotes co-operative transactivation of common target genes through a Smad3–Sp1–KLF6 …
LM Botella, F Sanz-Rodriguez, Y Komi, A Fernandez-l, E Varela, ...
Biochemical Journal 419 (2), 485-495, 2009
Characterization of the human Activin-A receptor type II-like kinase 1 (ACVRL1) promoter and its regulation by Sp1
EM Garrido-Martin, FJ Blanco, A Fernandez-L, C Langa, CP Vary, UE Lee, ...
BMC molecular biology 11 (1), 51, 2010
Mutation study of Spanish patients with hereditary hemorrhagic telangiectasia
A Fontalba, A Fernandez-L, E García-Alegria, V Albiñana, ...
BMC Medical Genetics 9 (1), 1-8, 2008
p27Kip1, a double-edged sword in Shh-mediated medulloblastoma: Tumor accelerator and suppressor
B Bhatia, A Malik, A Fernandez-L, AM Kenney
Cell Cycle 9 (21), 4307-4314, 2010
The Hippo in the room: a new look at a key pathway in cell growth and transformation
A Fernandez-L, AM Kenney
Cell cycle 9 (12), 2292-2299, 2010
Normal and oncogenic roles for microRNAs in the developing brain
A Fernandez-L, PA Northcott, MD Taylor, AM Kenney
Cell Cycle 8 (24), 4049-4054, 2009
The TGF-β co-receptor endoglin modulates the expression and transforming potential of H-Ras
JF Santibanez, E Pérez-Gómez, A Fernandez-L, EM Garrido-Martin, ...
Carcinogenesis 31 (12), 2145-2154, 2010
β-Arrestin-1 links mitogenic sonic hedgehog signaling to the cell cycle exit machinery in neural precursors
SR Parathath, LA Mainwaring, A Fernandez-L, CG Guldal, Z Nahlé, ...
Cell Cycle 9 (19), 4013-4024, 2010
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