Chanson Brumme
Chanson Brumme
Assistant Professor, Faculty of Medicine, University of British Columbia
Verified email at - Homepage
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The major genetic determinants of HIV-1 control affect HLA class I peptide presentation
International HIV Controllers Study
Science 330 (6010), 1551-1557, 2010
Predictors of HIV drug-resistance mutations in a large antiretroviral-naive cohort initiating triple antiretroviral therapy
PR Harrigan, RS Hogg, WWY Dong, B Yip, B Wynhoven, J Woodward, ...
The Journal of infectious diseases 191 (3), 339-347, 2005
Adaptation of HIV-1 to human leukocyte antigen class I
Y Kawashima, K Pfafferott, J Frater, P Matthews, R Payne, M Addo, ...
Nature 458 (7238), 641-645, 2009
Influence of HLA-C expression level on HIV control
R Apps, Y Qi, JM Carlson, H Chen, X Gao, R Thomas, Y Yuki, ...
Science 340 (6128), 87-91, 2013
Whole genome deep sequencing of HIV-1 reveals the impact of early minor variants upon immune recognition during acute infection
MR Henn, CL Boutwell, P Charlebois, NJ Lennon, KA Power, ...
PLoS pathogens 8 (3), e1002529, 2012
HLA-B57/B* 5801 human immunodeficiency virus type 1 elite controllers select for rare gag variants associated with reduced viral replication capacity and strong cytotoxic T …
T Miura, MA Brockman, A Schneidewind, M Lobritz, F Pereyra, A Rathod, ...
Journal of virology 83 (6), 2743-2755, 2009
Molecular and clinical epidemiology of CXCR4-using HIV-1 in a large population of antiretroviral-naive individuals
ZL Brumme, J Goodrich, HB Mayer, CJ Brumme, BM Henrick, ...
The Journal of infectious diseases 192 (3), 466-474, 2005
Antigen Load and Viral Sequence Diversification Determine the Functional Profile of HIV-1–Specific CD8+ T Cells
H Streeck, ZL Brumme, M Anastario, KW Cohen, JS Jolin, A Meier, ...
PLoS medicine 5 (5), e100, 2008
Human immunodeficiency virus type 1-specific CD8+ T-cell responses during primary infection are major determinants of the viral set point and loss of CD4+ T cells
H Streeck, JS Jolin, Y Qi, B Yassine-Diab, RC Johnson, DS Kwon, ...
Journal of virology 83 (15), 7641-7648, 2009
Marked epitope-and allele-specific differences in rates of mutation in human immunodeficiency type 1 (HIV-1) Gag, Pol, and Nef cytotoxic T-lymphocyte epitopes in acute/early …
ZL Brumme, CJ Brumme, J Carlson, H Streeck, M John, Q Eichbaum, ...
Journal of virology 82 (18), 9216-9227, 2008
Automating HIV drug resistance genotyping with RECall, a freely accessible sequence analysis tool
CK Woods, CJ Brumme, TF Liu, CKS Chui, AL Chu, B Wynhoven, TA Hall, ...
Journal of clinical microbiology 50 (6), 1936-1942, 2012
HLA-associated immune escape pathways in HIV-1 subtype B Gag, Pol and Nef proteins
ZL Brumme, M John, JM Carlson, CJ Brumme, D Chan, MA Brockman, ...
PloS one 4 (8), e6687, 2009
Evidence of differential HLA class I-mediated viral evolution in functional and accessory/regulatory genes of HIV-1
ZL Brumme, CJ Brumme, D Heckerman, BT Korber, M Daniels, J Carlson, ...
PLoS pathogens 3 (7), e94, 2007
Definition of the viral targets of protective HIV-1-specific T cell responses
B Mothe, A Llano, J Ibarrondo, M Daniels, C Miranda, J Zamarreño, ...
Journal of translational medicine 9, 1-20, 2011
Phylogenetic dependency networks: inferring patterns of CTL escape and codon covariation in HIV-1 Gag
JM Carlson, ZL Brumme, CM Rousseau, CJ Brumme, P Matthews, ...
PLoS computational biology 4 (11), e1000225, 2008
HLA-Associated Alterations in Replication Capacity of Chimeric NL4-3 Viruses Carrying gag-protease from Elite Controllers of Human Immunodeficiency Virus Type 1
T Miura, MA Brockman, ZL Brumme, CJ Brumme, F Pereyra, A Trocha, ...
Journal of virology 83 (1), 140-149, 2009
Genetic characterization of human immunodeficiency virus type 1 in elite controllers: lack of gross genetic defects or common amino acid changes
T Miura, MA Brockman, CJ Brumme, ZL Brumme, JM Carlson, F Pereyra, ...
Journal of virology 82 (17), 8422-8430, 2008
Early selection in Gag by protective HLA alleles contributes to reduced HIV-1 replication capacity that may be largely compensated for in chronic infection
MA Brockman, ZL Brumme, CJ Brumme, T Miura, J Sela, PC Rosato, ...
Journal of virology 84 (22), 11937-11949, 2010
Impaired replication capacity of acute/early viruses in persons who become HIV controllers
T Miura, ZL Brumme, MA Brockman, P Rosato, J Sela, CJ Brumme, ...
Journal of virology 84 (15), 7581-7591, 2010
A genome-to-genome analysis of associations between human genetic variation, HIV-1 sequence diversity, and viral control
I Bartha, JM Carlson, CJ Brumme, PJ McLaren, ZL Brumme, M John, ...
elife 2, e01123, 2013
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