| Physiology and pathophysiology of matrix metalloproteases T Klein, R Bischoff Amino acids 41, 271-290, 2011 | 1026 | 2011 |
| Determination of clenbuterol in bovine liver by combining matrix solid-phase dispersion and molecularly imprinted solid-phase extraction followed by liquid chromatography … C Crescenzi, S Bayoudh, PAG Cormack, T Klein, K Ensing Analytical chemistry 73 (10), 2171-2177, 2001 | 220 | 2001 |
| Active site specificity profiling of the matrix metalloproteinase family: Proteomic identification of 4300 cleavage sites by nine MMPs explored with structural and synthetic … U Eckhard, PF Huesgen, O Schilling, CL Bellac, GS Butler, JH Cox, ... Matrix biology 49, 37-60, 2016 | 208 | 2016 |
| Active metalloproteases of the A Disintegrin and Metalloprotease (ADAM) family: biological function and structure T Klein, R Bischoff Journal of proteome research 10 (1), 17-33, 2011 | 207 | 2011 |
| Proteolytic Cleavage Mechanisms, Function, and “Omic” Approaches for a Near-Ubiquitous Posttranslational Modification T Klein, U Eckhard, A Dufour, N Solis, CM Overall Chemical reviews 118 (3), 1137-1168, 2018 | 175 | 2018 |
| The paracaspase MALT1 cleaves HOIL1 reducing linear ubiquitination by LUBAC to dampen lymphocyte NF-κB signalling T Klein, SY Fung, F Renner, MA Blank, A Dufour, S Kang, M Bolger-Munro, ... Nature communications 6 (1), 8777, 2015 | 160 | 2015 |
| Increased arginase activity contributes to airway remodelling in chronic allergic asthma H Maarsingh, BGJ Dekkers, AB Zuidhof, IST Bos, MH Menzen, T Klein, ... European Respiratory Journal 38 (2), 318-328, 2011 | 122 | 2011 |
| Arginase inhibition prevents inflammation and remodeling in a guinea pig model of chronic obstructive pulmonary disease T Pera, AB Zuidhof, M Smit, MH Menzen, T Klein, G Flik, J Zaagsma, ... Journal of Pharmacology and Experimental Therapeutics 349 (2), 229-238, 2014 | 83 | 2014 |
| SEPIA–a new single pixel receiver at the APEX telescope V Belitsky, I Lapkin, M Fredrixon, D Meledin, E Sundin, B Billade, SE Ferm, ... Astronomy & astrophysics 612, A23, 2018 | 73 | 2018 |
| N-terminomics TAILS identifies host cell substrates of poliovirus and coxsackievirus B3 3C proteinases that modulate virus infection JM Jagdeo, A Dufour, T Klein, N Solis, O Kleifeld, J Kizhakkedathu, H Luo, ... Journal of virology 92 (8), 10.1128/jvi. 02211-17, 2018 | 71 | 2018 |
| C-terminal truncation of IFN-γ inhibits proinflammatory macrophage responses and is deficient in autoimmune disease A Dufour, CL Bellac, U Eckhard, N Solis, T Klein, R Kappelhoff, N Fortelny, ... Nature Communications 9 (1), 2416, 2018 | 70 | 2018 |
| Granzyme B is elevated in autoimmune blistering diseases and cleaves key anchoring proteins of the dermal-epidermal junction V Russo, T Klein, DJ Lim, N Solis, Y Machado, S Hiroyasu, L Nabai, ... Scientific reports 8 (1), 9690, 2018 | 62 | 2018 |
| An allosteric MALT1 inhibitor is a molecular corrector rescuing function in an immunodeficient patient J Quancard, T Klein, SY Fung, M Renatus, N Hughes, L Israël, JJ Priatel, ... Nature chemical biology 15 (3), 304-313, 2019 | 55 | 2019 |
| Cross-laboratory standardization of preclinical lipidomics using differential mobility spectrometry and multiple reaction monitoring M Ghorasaini, Y Mohammed, J Adamski, L Bettcher, JA Bowden, ... Analytical Chemistry 93 (49), 16369-16378, 2021 | 49 | 2021 |
| Solid-phase synthesis of succinylhydroxamate peptides: functionalized matrix metalloproteinase inhibitors MA Leeuwenburgh, PP Geurink, T Klein, HF Kauffman, GA van der Marel, ... Organic letters 8 (8), 1705-1708, 2006 | 40 | 2006 |
| DIPPER, a spatiotemporal proteomics atlas of human intervertebral discs for exploring ageing and degeneration dynamics V Tam, P Chen, A Yee, N Solis, T Klein, M Kudelko, R Sharma, ... Elife 9, e64940, 2020 | 39 | 2020 |
| Activity-based matrix metallo-protease enrichment using automated, inhibitor affinity extractions JR Freije, T Klein, JA Ooms, JP Franke, R Bischoff Journal of proteome research 5 (5), 1186-1194, 2006 | 39 | 2006 |
| An integrated high-performance liquid chromatography–mass spectrometry system for the activity-dependent analysis of matrix metalloproteases R Freije, T Klein, B Ooms, HF Kauffman, R Bischoff Journal of Chromatography A 1189 (1-2), 417-425, 2008 | 37 | 2008 |
| Functional proteomics on zinc‐dependent metalloproteinases using inhibitor probes T Klein, P P. Geurink, H S. Overkleeft, H K. Kauffman, R Bischoff ChemMedChem: Chemistry Enabling Drug Discovery 4 (2), 164-170, 2009 | 31 | 2009 |
| Lipid signature of advanced human carotid atherosclerosis assessed by mass spectrometry imaging AM Moerman, M Visscher, N Slijkhuis, K Van Gaalen, B Heijs, T Klein, ... Journal of lipid research 62, 2021 | 30 | 2021 |
Christopher M OverallUniversity of British ColumbiaVerified email at ubc.ca
