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Pavel Gershkovich
Pavel Gershkovich
Verified email at nottingham.ac.uk - Homepage
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Year
Uptake of lipophilic drugs by plasma derived isolated chylomicrons: linear correlation with intestinal lymphatic bioavailability
P Gershkovich, A Hoffman
European journal of pharmaceutical sciences 26 (5), 394-404, 2005
1682005
Dietary fats and pharmaceutical lipid excipients increase systemic exposure to orally administered cannabis and cannabis-based medicines
A Zgair, JCM Wong, JB Lee, J Mistry, O Sivak, KM Wasan, IM Hennig, ...
American journal of translational research 8 (8), 3448, 2016
1632016
Characterisation of human saliva as a platform for oral dissolution medium development
S Gittings, N Turnbull, B Henry, CJ Roberts, P Gershkovich
European Journal of Pharmaceutics and Biopharmaceutics 91, 16-24, 2015
1592015
Development and characterization of oral lipid-based amphotericin B formulations with enhanced drug solubility, stability and antifungal activity in rats infected with …
EK Wasan, K Bartlett, P Gershkovich, O Sivak, B Banno, Z Wong, ...
International journal of pharmaceutics 372 (1-2), 76-84, 2009
1382009
Oral administration of cannabis with lipids leads to high levels of cannabinoids in the intestinal lymphatic system and prominent immunomodulation
A Zgair, JB Lee, JCM Wong, DA Taha, J Aram, D Di Virgilio, JW McArthur, ...
Scientific Reports 7 (1), 14542, 2017
1172017
Highly effective oral amphotericin B formulation against murine visceral leishmaniasis
KM Wasan, EK Wasan, P Gershkovich, X Zhu, RR Tidwell, KA Werbovetz, ...
Journal of Infectious Diseases 200 (3), 357-360, 2009
1092009
The role of the lymphatic system in subcutaneous absorption of macromolecules in the rat model
L Kagan, P Gershkovich, A Mendelman, S Amsili, N Ezov, A Hoffman
European journal of pharmaceutics and biopharmaceutics 67 (3), 759-765, 2007
1092007
Dissolution methodology for taste masked oral dosage forms
S Gittings, N Turnbull, CJ Roberts, P Gershkovich
Journal of controlled release 173, 32-42, 2014
1032014
Effect of a high-fat meal on absorption and disposition of lipophilic compounds: the importance of degree of association with triglyceride-rich lipoproteins
P Gershkovich, A Hoffman
European journal of pharmaceutical sciences 32 (1), 24-32, 2007
1032007
Pharmacokinetics and biodistribution of amphotericin B in rats following oral administration in a novel lipid-based formulation
P Gershkovich, EK Wasan, M Lin, O Sivak, CG Leon, JG Clement, ...
Journal of antimicrobial chemotherapy 64 (1), 101-108, 2009
932009
A review of the application of lipid-based systems in systemic, dermal/transdermal, and ocular drug delivery
P Gershkovich, KM Wasan, CA Barta
Critical Reviews™ in Therapeutic Drug Carrier Systems 25 (6), 2008
872008
Quantitative analysis of lab-to-lab variability in Caco-2 permeability assays
JB Lee, A Zgair, DA Taha, X Zang, L Kagan, TH Kim, MG Kim, H Yun, ...
European Journal of Pharmaceutics and Biopharmaceutics 114, 38-42, 2017
822017
Chain length affects pancreatic lipase activity and the extent and pH–time profile of triglyceride lipolysis
P Benito-Gallo, A Franceschetto, JCM Wong, M Marlow, V Zann, ...
European journal of pharmaceutics and biopharmaceutics 93, 353-362, 2015
752015
Development of a simple and sensitive HPLC–UV method for the simultaneous determination of cannabidiol and Δ9-tetrahydrocannabinol in rat plasma
A Zgair, JCM Wong, A Sabri, PM Fischer, DA Barrett, CS Constantinescu, ...
Journal of Pharmaceutical and Biomedical Analysis 114, 145-151, 2015
732015
A novel tropically stable oral amphotericin B formulation (iCo-010) exhibits efficacy against visceral Leishmaniasis in a murine model
EK Wasan, P Gershkovich, J Zhao, X Zhu, K Werbovetz, RR Tidwell, ...
PLoS neglected tropical diseases 4 (12), e913, 2010
632010
Translational insight into statin-induced muscle toxicity: from cell culture to clinical studies
DA Taha, CH De Moor, DA Barrett, P Gershkovich
Translational Research 164 (2), 85-109, 2014
582014
Lipophilic activated ester prodrug approach for drug delivery to the intestinal lymphatic system
JB Lee, A Zgair, J Malec, TH Kim, MG Kim, J Ali, C Qin, W Feng, M Chiang, ...
Journal of controlled release 286, 10-19, 2018
542018
In vitro anticancer properties and biological evaluation of novel natural alkaloid jerantinine B
ME Qazzaz, VJ Raja, KH Lim, TS Kam, JB Lee, P Gershkovich, ...
Cancer Letters 370 (2), 185-197, 2016
532016
Different impacts of intestinal lymphatic transport on the oral bioavailability of structurally similar synthetic lipophilic cannabinoids: dexanabinol and PRS-211,220
P Gershkovich, B Qadri, A Yacovan, S Amselem, A Hoffman
european journal of pharmaceutical sciences 31 (5), 298-305, 2007
492007
Long-circulating non-toxic blood pool imaging agent based on hyperbranched polyglycerols
K Saatchi, N Gelder, P Gershkovich, O Sivak, KM Wasan, RK Kainthan, ...
International journal of pharmaceutics 422 (1-2), 418-427, 2012
432012
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