Domain-focused CRISPR screen identifies HRI as a fetal hemoglobin regulator in human erythroid cells JD Grevet, X Lan, N Hamagami, CR Edwards, L Sankaranarayanan, X Ji, ... Science 361 (6399), 285-290, 2018 | 142 | 2018 |
Structural and functional similarities of calcium homeostasis modulator 1 (CALHM1) ion channel with connexins, pannexins, and innexins AP Siebert, Z Ma, JD Grevet, A Demuro, I Parker, JK Foskett Journal of Biological Chemistry 288 (9), 6140-6153, 2013 | 125 | 2013 |
Comparative analysis of three-dimensional chromosomal architecture identifies a novel fetal hemoglobin regulatory element P Huang, CA Keller, B Giardine, JD Grevet, JOJ Davies, JR Hughes, ... Genes & development 31 (16), 1704-1713, 2017 | 124 | 2017 |
ZNF410 uniquely activates the NuRD component CHD4 to silence fetal hemoglobin expression X Lan, R Ren, R Feng, LC Ly, Y Lan, Z Zhang, N Aboreden, K Qin, ... Molecular cell 81 (2), 239-254. e8, 2021 | 57 | 2021 |
Cerebrospinal fluid biomarkers in idiopathic normal pressure hydrocephalus V Leinonen, LG Menon, RS Carroll, D Dello Iacono, J Grevet, ... International journal of Alzheimer’s disease 2011, 2011 | 49 | 2011 |
The E3 ligase adaptor molecule SPOP regulates fetal hemoglobin levels in adult erythroid cells X Lan, E Khandros, P Huang, SA Peslak, SK Bhardwaj, JD Grevet, ... Blood Advances 3 (10), 1586-1597, 2019 | 31 | 2019 |
HRI depletion cooperates with pharmacologic inducers to elevate fetal hemoglobin and reduce sickle cell formation SA Peslak, E Khandros, P Huang, X Lan, CL Geronimo, JD Grevet, ... Blood Advances 4 (18), 4560-4572, 2020 | 16 | 2020 |
Genome editing recreates hereditary persistence of fetal hemoglobin in primary human erythroblasts E Traxler, Y Yao, C Li, J Grevet, P Huang, S Wright, GA Blobel, MJ Weiss Blood 126 (23), 640, 2015 | 9 | 2015 |
Knotted and Linked Products of recombination on T (2, n)# T (2, m) Substrates E Flapan, J Grevet, Q Li, CD Sun, H Wong | 3 | 2014 |
Domain-focused CRISPR-Cas9 screen identifies the E3 ubiquitin ligase substrate adaptor protein SPOP as a novel repressor of fetal hemoglobin X Lan, E Khandros, JD Grevet, SA Peslak, S Bhardwaj, CA Keller, ... Blood 132 (Supplement 1), 414-414, 2018 | 1 | 2018 |
Knotted and linked products of recombination on substrates E Flapan, J Grevet, Q Li, C Sun, H Wong arXiv preprint arXiv:1311.5456, 2013 | 1 | 2013 |
Compositions and methods for hemoglobin production G Blobel, J Grevet, J Shi, C Vakoc US Patent App. 17/532,123, 2022 | | 2022 |
Compositions and methods for hemoglobin production G Blobel, J Grevet, J Shi, C Vakoc US Patent 11,179,379, 2021 | | 2021 |
Heme-Regulated Inhibitor (HRI) Depletion Cooperates with Pharmacologic Inducers to Strongly Elevate Fetal Hemoglobin and Reduce Sickle Cell Formation SA Peslak, X Lan, E Khandros, P Huang, JA Yano, JD Grevet, ... Blood 134, 3557, 2019 | | 2019 |
Interrogating RNA Binding Proteins as Novel Regulators of Fetal Hemoglobin Expression A Wakabayashi, JD Grevet, X Lan, M Sharma, J Shi, GA Blobel Blood 134, 966, 2019 | | 2019 |
Heme-Regulated Inhibitor (HRI) Loss and Pharmacologic Treatments Cooperate to Strongly Elevate Fetal Hemoglobin and Reduce Sickle Cell Formation SA Peslak, JD Grevet, X Lan, O Abdulmalik, J Shi, GA Blobel Blood 132, 721, 2018 | | 2018 |
Compositions and methods for hemoglobin production G Blobel, J GREVET, J Shi, C Vakoc | | 2018 |
Domain-Focused CRISPR-Cas9 Screen Identifies Hri Kinase As a Regulator of Fetal Hemoglobin in Adult Human Erythroid Cells JD Grevet, N Hamagami, X Lan, L Sankaranarayanan, S Bhardwaj, ... Blood 130, 536, 2017 | | 2017 |
Mechanistic Insights into Forced Chromatin Looping Mediated Activation of Fetal Globin Gene Expression C Bartman, GA Blobel, J Grevet, CCS Hsiung, JW Rupon, A Raj Blood 124 (21), 331, 2014 | | 2014 |
Keeping fetal hemoglobin in the loop JD Grevet, GA Blobel Cell Cycle 13 (20), 3153-3154, 2014 | | 2014 |