Adrian  M. Dubuc, Ph.D
Adrian M. Dubuc, Ph.D
Brigham and Women's Hospital and Harvard Medical School
Verified email at bwh.harvard.edu
Title
Cited by
Cited by
Year
Subgroup-specific structural variation across 1,000 medulloblastoma genomes
PA Northcott, DJH Shih, J Peacock, L Garzia, AS Morrissy, T Zichner, ...
Nature 488 (7409), 49-56, 2012
6432012
Epigenomic alterations define lethal CIMP-positive ependymomas of infancy
SC Mack, H Witt, RM Piro, L Gu, S Zuyderduyn, AM Stütz, X Wang, ...
Nature 506 (7489), 445-450, 2014
4362014
Multiple recurrent genetic events converge on control of histone lysine methylation in medulloblastoma
PA Northcott, Y Nakahara, X Wu, L Feuk, DW Ellison, S Croul, S Mack, ...
Nature genetics 41 (4), 465-472, 2009
4152009
Clonal selection drives genetic divergence of metastatic medulloblastoma
X Wu, PA Northcott, A Dubuc, AJ Dupuy, DJH Shih, H Witt, S Croul, ...
Nature 482 (7386), 529-533, 2012
3962012
The eEF2 kinase confers resistance to nutrient deprivation by blocking translation elongation
G Leprivier, M Remke, B Rotblat, A Dubuc, ARF Mateo, M Kool, ...
Cell 153 (5), 1064-1079, 2013
2962013
Rapid, reliable, and reproducible molecular sub-grouping of clinical medulloblastoma samples
PA Northcott, DJH Shih, M Remke, YJ Cho, M Kool, C Hawkins, ...
Acta neuropathologica 123 (4), 615-626, 2012
2812012
Recurrence patterns across medulloblastoma subgroups: an integrated clinical and molecular analysis
V Ramaswamy, M Remke, E Bouffet, CC Faria, S Perreault, YJ Cho, ...
The lancet oncology 14 (12), 1200-1207, 2013
2292013
Cytogenetic prognostication within medulloblastoma subgroups
DJH Shih, PA Northcott, M Remke, A Korshunov, V Ramaswamy, M Kool, ...
Journal of clinical oncology 32 (9), 886, 2014
2232014
Pediatric and adult sonic hedgehog medulloblastomas are clinically and molecularly distinct
PA Northcott, T Hielscher, A Dubuc, S Mack, D Shih, M Remke, ...
Acta neuropathologica 122 (2), 231-240, 2011
1952011
TERT promoter mutations are highly recurrent in SHH subgroup medulloblastoma
M Remke, V Ramaswamy, J Peacock, DJH Shih, C Koelsche, ...
Acta neuropathologica 126 (6), 917-929, 2013
1282013
Aberrant patterns of H3K4 and H3K27 histone lysine methylation occur across subgroups in medulloblastoma
AM Dubuc, M Remke, A Korshunov, PA Northcott, SH Zhan, ...
Acta neuropathologica 125 (3), 373-384, 2013
1222013
Molecular subgroups of medulloblastoma
PA Northcott, AM Dubuc, S Pfister, MD Taylor
Expert review of neurotherapeutics 12 (7), 871-884, 2012
1132012
MicroRNA 218 acts as a tumor suppressor by targeting multiple cancer phenotype-associated genes in medulloblastoma
S Venkataraman, DK Birks, I Balakrishnan, I Alimova, PS Harris, PR Patel, ...
Journal of Biological Chemistry 288 (3), 1918-1928, 2013
1072013
Differential expression of microRNA species in organs of hibernating ground squirrels: a role in translational suppression during torpor
A Dubuc, KB Storey
Biochimica et Biophysica Acta (BBA)-Gene Regulatory Mechanisms 1779 (10 …, 2008
852008
Polo-like kinase 1 (PLK1) inhibition suppresses cell growth and enhances radiation sensitivity in medulloblastoma cells
PS Harris, S Venkataraman, I Alimova, DK Birks, AM Donson, J Knipstein, ...
BMC cancer 12 (1), 1-13, 2012
802012
The genetics of pediatric brain tumors
AM Dubuc, PA Northcott, S Mack, H Witt, S Pfister, MD Taylor
Current neurology and neuroscience reports 10 (3), 215-223, 2010
792010
MicroRNA regulation below zero: differential expression of miRNA-21 and miRNA-16 during freezing in wood frogs
KK Biggar, A Dubuc, K Storey
Cryobiology 59 (3), 317-321, 2009
652009
Targeting the enhancer of zeste homologue 2 in medulloblastoma
I Alimova, S Venkataraman, P Harris, VE Marquez, PA Northcott, A Dubuc, ...
International journal of cancer 131 (8), 1800-1809, 2012
642012
Medulloblastoma subgroups remain stable across primary and metastatic compartments
X Wang, AM Dubuc, V Ramaswamy, S Mack, DMA Gendoo, M Remke, ...
Acta neuropathologica 129 (3), 449-457, 2015
622015
Voltage-gated potassium channel EAG2 controls mitotic entry and tumor growth in medulloblastoma via regulating cell volume dynamics
X Huang, AM Dubuc, R Hashizume, J Berg, Y He, J Wang, C Chiang, ...
Genes & development 26 (16), 1780-1796, 2012
612012
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Articles 1–20