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Alec J. Walker
Alec J. Walker
Graduate student, Harvard University
Verified email at g.harvard.edu
Title
Cited by
Cited by
Year
4-1BB costimulation ameliorates T cell exhaustion induced by tonic signaling of chimeric antigen receptors
AH Long, WM Haso, JF Shern, KM Wanhainen, M Murgai, M Ingaramo, ...
Nature medicine 21 (6), 581-590, 2015
15822015
Single-cell RNA sequencing of microglia throughout the mouse lifespan and in the injured brain reveals complex cell-state changes
TR Hammond, C Dufort, L Dissing-Olesen, S Giera, A Young, A Wysoker, ...
Immunity 50 (1), 253-271. e6, 2019
15422019
CD47 protects synapses from excess microglia-mediated pruning during development
EK Lehrman, DK Wilton, EY Litvina, CA Welsh, ST Chang, A Frouin, ...
Neuron 100 (1), 120-134. e6, 2018
3642018
Tumor antigen and receptor densities regulate efficacy of a chimeric antigen receptor targeting anaplastic lymphoma kinase
AJ Walker, RG Majzner, L Zhang, K Wanhainen, AH Long, SM Nguyen, ...
Molecular Therapy 25 (9), 2189-2201, 2017
3172017
Reduction of MDSCs with all-trans retinoic acid improves CAR therapy efficacy for sarcomas
AH Long, SL Highfill, Y Cui, JP Smith, AJ Walker, S Ramakrishna, ...
Cancer immunology research 4 (10), 869-880, 2016
2942016
Dissection of artifactual and confounding glial signatures by single-cell sequencing of mouse and human brain
SE Marsh, AJ Walker, T Kamath, L Dissing-Olesen, TR Hammond, ...
Nature neuroscience 25 (3), 306-316, 2022
1852022
CCR2-dependent dendritic cell accumulation in the central nervous system during early effector experimental autoimmune encephalomyelitis is essential for effector T cell …
BD Clarkson, A Walker, MG Harris, A Rayasam, M Sandor, Z Fabry
The Journal of Immunology 194 (2), 531-541, 2015
652015
CCR7 deficient inflammatory dendritic cells are retained in the central nervous system
BD Clarkson, A Walker, MG Harris, A Rayasam, M Hsu, M Sandor, ...
Scientific reports 7 (1), 42856, 2017
502017
A RIPK1-regulated inflammatory microglial state in amyotrophic lateral sclerosis
L Mifflin, Z Hu, C Dufort, CC Hession, AJ Walker, K Niu, H Zhu, N Liu, ...
Proceedings of the National Academy of Sciences 118 (13), e2025102118, 2021
482021
Mapping the accumulation of co-infiltrating CNS dendritic cells and encephalitogenic T cells during EAE
BD Clarkson, A Walker, M Harris, A Rayasam, M Sandor, Z Fabry
Journal of neuroimmunology 277 (1-2), 39-49, 2014
322014
Bacteria hijack a meningeal neuroimmune axis to facilitate brain invasion
FA Pinho-Ribeiro, L Deng, DV Neel, O Erdogan, H Basu, D Yang, S Choi, ...
Nature 615 (7952), 472-481, 2023
292023
Single cell sequencing reveals glial specific responses to tissue processing & enzymatic dissociation in mice and humans
SE Marsh, T Kamath, AJ Walker, L Dissing-Olesen, TR Hammond, ...
Biorxiv, 2020.12. 03.408542, 2020
282020
Reduction of MDSCs with all-trans retinoic acid improves CAR therapy efficacy for sarcomas. Cancer Immunol Res.(2016) 4: 869–80. doi: 10.1158/2326-6066
AH Long, SL Highfill, Y Cui, JP Smith, AJ Walker, S Ramakrishna, ...
CIR-15-0230, 0
20
Complex cell-state changes revealed by single cell RNA sequencing of 76,149 microglia throughout the mouse lifespan and in the injured brain
TR Hammond, C Dufort, L Dissing-Olesen, S Giera, A Young, A Wysoker, ...
bioRxiv, 406140, 2018
92018
Chimeric antigen receptor T-cell therapy against anaplastic lymphoma kinase (ALK) is limited by target antigen density and CAR surface expression
RG Majzner, AJ Walker, M Murgai, L Zhang, AH Long, KM Wanhainen, ...
Cancer Research 76 (14_Supplement), 2648-2648, 2016
42016
CCR2-dependent dendritic cell accumulation in CNS during early effector EAE is essential for effector T cell restimulation in situ and disease progression
BD Clarkson, A Walker, MG Harris, A Rayasam, M Sandor, Z Fabry
Journal of immunology (Baltimore, Md.: 1950) 194 (2), 531, 2015
32015
FEAST: A flow cytometry-based toolkit for interrogating microglial engulfment of synaptic and myelin proteins
L Dissing-Olesen, AJ Walker, Q Feng, HJ Barr, AC Walker, L Xie, ...
Nature Communications 14 (1), 6015, 2023
22023
4-1BB costimulation ameliorates exhaustion and prolongs in vivo persistence of chimeric antigen receptor (CAR) expressing T cells
AH Long, WM Haso, JP Smith, AJ Walker, TJ Fry, RJ Orentas, CL Mackall
Cancer Research 75 (15_Supplement), 4702-4702, 2015
12015
Migration of ic injected BMDCs from brain to deep cervical lymph nodes is CCR7 dependent but does not promote EAE disease progression (CCR1P. 244)
B Clarkson, A Rayasam, A Walker, M Harris, M Sandor, Z Fabry
The Journal of Immunology 192 (1_Supplement), 48.4-48.4, 2014
12014
CCR2-dependent dendritic cell recruitment to CNS tissues during EAE promotes disease progression and inflammatory cytokine production by CNS T cells (CCR1P. 243)
B Clarkson, A Rayasam, A Walker, M Harris, M Sandor, Z Fabry
The Journal of Immunology 192 (1_Supplement), 48.3-48.3, 2014
12014
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Articles 1–20