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Michel Leroux
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Genes and molecular pathways underpinning ciliopathies
JF Reiter, MR Leroux
Nature reviews Molecular cell biology 18 (9), 533-547, 2017
12462017
Comparative genomics identifies a flagellar and basal body proteome that includes the BBS5 human disease gene
JB Li, JM Gerdes, CJ Haycraft, Y Fan, TM Teslovich, H May-Simera, H Li, ...
Cell 117 (4), 541-552, 2004
8632004
Basal body dysfunction is a likely cause of pleiotropic Bardet–Biedl syndrome
SJ Ansley, JL Badano, OE Blacque, J Hill, BE Hoskins, CC Leitch, ...
Nature 425 (6958), 628-633, 2003
8242003
The centrosomal protein nephrocystin-6 is mutated in Joubert syndrome and activates transcription factor ATF4
JA Sayer, EA Otto, JF O'Toole, G Nurnberg, MA Kennedy, C Becker, ...
Nature genetics 38 (6), 674-681, 2006
7252006
Disruption of Bardet-Biedl syndrome ciliary proteins perturbs planar cell polarity in vertebrates
AJ Ross, H May-Simera, ER Eichers, M Kai, J Hill, DJ Jagger, CC Leitch, ...
Nature genetics 37 (10), 1135-1140, 2005
6732005
The base of the cilium: roles for transition fibres and the transition zone in ciliary formation, maintenance and compartmentalization
JF Reiter, OE Blacque, MR Leroux
EMBO reports 13 (7), 608-618, 2012
5262012
MKS and NPHP modules cooperate to establish basal body/transition zone membrane associations and ciliary gate function during ciliogenesis
CL Williams, C Li, K Kida, PN Inglis, S Mohan, L Semenec, NJ Bialas, ...
Journal of Cell Biology 192 (6), 1023-1041, 2011
5022011
The Bardet-Biedl protein BBS4 targets cargo to the pericentriolar region and is required for microtubule anchoring and cell cycle progression
JC Kim, JL Badano, S Sibold, MA Esmail, J Hill, BE Hoskins, CC Leitch, ...
Nature genetics 36 (5), 462-470, 2004
4562004
Loss of C. elegans BBS-7 and BBS-8 protein function results in cilia defects and compromised intraflagellar transport
OE Blacque, MJ Reardon, C Li, J McCarthy, MR Mahjoub, SJ Ansley, ...
Genes & development 18 (13), 1630-1642, 2004
4492004
Functional coordination of intraflagellar transport motors
G Ou, O E. Blacque, JJ Snow, MR Leroux, JM Scholey
Nature 436 (7050), 583-587, 2005
4472005
Mutations in a member of the Ras superfamily of small GTP-binding proteins causes Bardet-Biedl syndrome
Y Fan, MA Esmail, SJ Ansley, OE Blacque, K Boroevich, AJ Ross, ...
Nature genetics 36 (9), 989-993, 2004
3862004
Structure of the molecular chaperone prefoldin: unique interaction of multiple coiled coil tentacles with unfolded proteins
R Siegert, MR Leroux, C Scheufler, FU Hartl, I Moarefi
Cell 103 (4), 621-632, 2000
3692000
Functional genomics of the cilium, a sensory organelle
OE Blacque, EA Perens, KA Boroevich, PN Inglis, C Li, A Warner, ...
Current Biology 15 (10), 935-941, 2005
3222005
Structure-function studies on small heat shock protein oligomeric assembly and interaction with unfolded polypeptides
MR Leroux, R Melki, B Gordon, G Batelier, EPM Candido
Journal of Biological Chemistry 272 (39), 24646-24656, 1997
3021997
Piecing together a ciliome
PN Inglis, KA Boroevich, MR Leroux
TRENDS in Genetics 22 (9), 491-500, 2006
2672006
Compartmentation of protein folding in vivo: sequestration of non‐native polypeptide by the chaperonin–GimC system
K Siegers, T Waldmann, MR Leroux, K Grein, A Shevchenko, E Schiebel, ...
The EMBO journal, 1999
2641999
The sensory cilia of Caenorhabditis elegans.
PN Inglis, G Ou, MR Leroux, JM Scholey
WormBook, 1, 2007
2622007
Heterozygous mutations in BBS1, BBS2 and BBS6 have a potential epistatic effect on Bardet–Biedl patients with two mutations at a second BBS locus
JL Badano, JC Kim, BE Hoskins, RA Lewis, SJ Ansley, DJ Cutler, ...
Human molecular genetics 12 (14), 1651-1659, 2003
2392003
Analysis of xbx genes in C. elegans
E Efimenko, K Bubb, HY Mak, T Holzman, MR Leroux, G Ruvkun, ...
Oxford University Press for The Company of Biologists Limited 132 (8), 1923-1934, 2005
2372005
Defects in the IFT-B component IFT172 cause Jeune and Mainzer-Saldino syndromes in humans
J Halbritter, AA Bizet, M Schmidts, JD Porath, DA Braun, HY Gee, ...
The American Journal of Human Genetics 93 (5), 915-925, 2013
2342013
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