Marina Sirota
Marina Sirota
Assistant Professor, Bakar Computational Health Sciences Institute, UCSF
Verified email at ucsf.edu
TitleCited byYear
Evolution of genes and genomes on the Drosophila phylogeny
Drosophila 12 Genomes Consortium
Nature 450 (7167), 203, 2007
17882007
Ten years of pathway analysis: current approaches and outstanding challenges
P Khatri, M Sirota, AJ Butte
PLoS computational biology 8 (2), e1002375, 2012
10352012
Identifying a high fraction of the human genome to be under selective constraint using GERP++
EV Davydov, DL Goode, M Sirota, GM Cooper, A Sidow, S Batzoglou
PLoS computational biology 6 (12), e1001025, 2010
8952010
Discovery and preclinical validation of drug indications using compendia of public gene expression data
M Sirota, JT Dudley, J Kim, AP Chiang, AA Morgan, A Sweet-Cordero, ...
Science translational medicine 3 (96), 96ra77-96ra77, 2011
5272011
Computational repositioning of the anticonvulsant topiramate for inflammatory bowel disease
JT Dudley, M Sirota, M Shenoy, RK Pai, S Roedder, AP Chiang, ...
Science translational medicine 3 (96), 96ra76-96ra76, 2011
3862011
Systematic pan-cancer analysis of tumour purity
D Aran, M Sirota, AJ Butte
Nature communications 6, 8971, 2015
2742015
Autoimmune disease classification by inverse association with SNP alleles
M Sirota, MA Schaub, S Batzoglou, WH Robinson, AJ Butte
PLoS genetics 5 (12), e1000792, 2009
1422009
B cell exchange across the blood-brain barrier in multiple sclerosis
H von Büdingen, TC Kuo, M Sirota, CJ van Belle, L Apeltsin, J Glanville, ...
The Journal of Clinical Investigation, 2012
1412012
Immunoglobulin class-switched B cells form an active immune axis between CNS and periphery in multiple sclerosis
A Palanichamy, L Apeltsin, TC Kuo, M Sirota, S Wang, SJ Pitts, ...
Science translational medicine 6 (248), 248ra106-248ra106, 2014
1302014
Non-synonymous and synonymous coding SNPs show similar likelihood and effect size of human disease association
R Chen, EV Davydov, M Sirota, AJ Butte
PloS one 5 (10), e13574, 2010
1262010
CONTRAST: a discriminative, phylogeny-free approach to multiple informant de novo gene prediction
SS Gross, CB Do, M Sirota, S Batzoglou
Genome biology 8 (12), R269, 2007
1132007
Expression-based genome-wide association study links the receptor CD44 in adipose tissue with type 2 diabetes
K Kodama, M Horikoshi, K Toda, S Yamada, K Hara, J Irie, M Sirota, ...
Proceedings of the National Academy of Sciences 109 (18), 7049-7054, 2012
1052012
Cross-tissue analysis of gene and protein expression in normal and cancer tissues
I Kosti, N Jain, D Aran, AJ Butte, M Sirota
Scientific reports 6, 24799, 2016
642016
Drug discovery in a multidimensional world: systems, patterns, and networks
JT Dudley, E Schadt, M Sirota, AJ Butte, E Ashley
Journal of cardiovascular translational research 3 (5), 438-447, 2010
642010
Comprehensive analysis of normal adjacent to tumor transcriptomes
D Aran, R Camarda, J Odegaard, H Paik, B Oskotsky, G Krings, A Goga, ...
Nature communications 8 (1), 1077, 2017
632017
Sex differences in disease risk from reported genome-wide association study findings
LY Liu, MA Schaub, M Sirota, AJ Butte
Human genetics 131 (3), 353-364, 2012
462012
Reversal of cancer gene expression correlates with drug efficacy and reveals therapeutic targets
B Chen, L Ma, H Paik, M Sirota, W Wei, MS Chua, S So, AJ Butte
Nature communications 8, 16022, 2017
402017
Environmental influences on reproductive health: the importance of chemical exposures
A Wang, A Padula, M Sirota, TJ Woodruff
Fertility and sterility 106 (4), 905-929, 2016
402016
Relating chemical structure to cellular response: an integrative analysis of gene expression, bioactivity, and structural data across 11,000 compounds
B Chen, P Greenside, H Paik, M Sirota, D Hadley, AJ Butte
CPT: pharmacometrics & systems pharmacology 4 (10), 576-584, 2015
362015
Characteristics of drug combination therapy in oncology by analyzing clinical trial data on ClinicalTrials. gov
M Wu, M Sirota, AJ Butte, BIN Chen
Pacific Symposium on Biocomputing Co-Chairs, 68-79, 2014
362014
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Articles 1–20