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Michelle Di Paola
Michelle Di Paola
The Hospital for Sick Children, The University of Toronto, Ted Rogers Centre for Heart Research
Verified email at mail.utoronto.ca
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Cited by
Cited by
Year
Orkambi® and amplifier co‐therapy improves function from a rare CFTR mutation in gene‐edited cells and patient tissue
SV Molinski, S Ahmadi, W Ip, H Ouyang, A Villella, JP Miller, PS Lee, ...
EMBO molecular medicine 9 (9), 1224-1243, 2017
1052017
Phenotypic profiling of CFTR modulators in patient-derived respiratory epithelia
S Ahmadi, Z Bozoky, M Di Paola, S Xia, C Li, AP Wong, L Wellhauser, ...
NPJ genomic medicine 2 (1), 12, 2017
682017
Synergy of cAMP and calcium signaling pathways in CFTR regulation
Z Bozoky, S Ahmadi, T Milman, TH Kim, K Du, M Di Paola, S Pasyk, ...
Proceedings of the national academy of sciences 114 (11), E2086-E2095, 2017
622017
SLC6A14 Is a Genetic Modifier of Cystic Fibrosis That Regulates Pseudomonas aeruginosa Attachment to Human Bronchial Epithelial Cells
M Di Paola, AJ Park, S Ahmadi, EJ Roach, YS Wu, M Struder-Kypke, ...
MBio 8 (6), 10.1128/mbio. 02073-17, 2017
482017
SLC6A14, an amino acid transporter, modifies the primary CF defect in fluid secretion
S Ahmadi, S Xia, YS Wu, M Di Paola, R Kissoon, C Luk, F Lin, K Du, ...
Elife 7, e37963, 2018
352018
A new platform for high-throughput therapy testing on iPSC-derived lung progenitor cells from cystic fibrosis patients
JX Jiang, L Wellhauser, O Laselva, I Utkina, Z Bozoky, T Gunawardena, ...
Stem cell reports 16 (11), 2825-2837, 2021
222021
Augmentation of cystic fibrosis transmembrane conductance regulator function in human bronchial epithelial cells via SLC6A14-dependent amino acid uptake. Implications for …
S Ahmadi, YS Wu, M Li, W Ip, A Lloyd-Kuzik, M Di Paola, K Du, S Xia, ...
American journal of respiratory cell and molecular biology 61 (6), 755-764, 2019
142019
Bioinformatic analysis of membrane and associated proteins in murine cardiomyocytes and human myocardium
SH Lee, S Hadipour-Lakmehsari, DH Kim, M Di Paola, U Kuzmanov, ...
Scientific Data 7 (1), 425, 2020
122020
Conversion of human and mouse fibroblasts into lung-like epithelial cells
AP Wong, S Shojaie, Q Liang, S Xia, M Di Paola, S Ahmadi, C Bilodeau, ...
Scientific reports 9 (1), 9027, 2019
122019
Tmem65 is critical for the structure and function of the intercalated discs in mouse hearts
ACT Teng, L Gu, M Di Paola, R Lakin, ZJ Williams, A Au, W Chen, ...
Nature Communications 13 (1), 6166, 2022
92022
High-throughput functional analysis of CFTR and other apically localized proteins in iPSC-derived human intestinal organoids
S Xia, Z Bozóky, M Di Paola, O Laselva, S Ahmadi, JX Jiang, AL Pitstick, ...
Cells 10 (12), 3419, 2021
82021
High-throughput functional analysis of CFTR and other apically localized channels in iPSC derived intestinal organoids
S Xia, Z Bozóky, O Laselva, M Di Paola, S Ahmadi, JX Jiang, A Pitstick, ...
bioRxiv, 2021.07. 07.451180, 2021
52021
Phenotypic profiling of CFTR modulators in patient-derived respiratory epithelia. npj Genomic Medicine. 2
S Ahmadi, Z Bozoky, M Di Paola, S Xia, C Li, AP Wong, L Wellhauser, ...
DOI: https://doi. org/10.1038/s41525-017-0015-6, PMID 28649446, 2017
42017
Augmentation of CFTR function in human bronchial epithelial cells via SLC6A14-dependent amino acid uptake: implications for treatment of cystic fibrosis
S Ahmadi, YS Wu, M Li, W Ip, A Lloyd-Kuzik, M Di Paola
Am J Respir Cell Mol Biol 10, 2019
32019
Noninvasive Quantification of Contractile Dynamics in Cardiac Cells, Spheroids, and Organs-on-a-Chip Using High-Frequency Ultrasound
EM Strohm, NI Callaghan, Y Ding, N Latifi, N Rafatian, S Funakoshi, ...
ACS nano 18 (1), 314-327, 2023
22023
SLC6A14 Modifies Fluid Secretory Capacity of Cystic Fibrosis Affected Epithelium by Enhancing CFTR Channel Function
S Ahmadi, C Luk, S Xia, M Di Paola, T Chung, J Rommens, C Bear
Biophysical Journal 108 (2), 19a-20a, 2015
22015
SLC6A14 Enhances CFTR Channel Activity in the Cystic Fibrosis Affected Lung Epithelium
S Ahmadi, S Xia, M Di Paola, W Ip, J Rommens, T Gonska, CE Bear
Biophysical Journal 110 (3), 452a, 2016
12016
Abstract P1027: Confocal And Mass Spectrometry-based Investigation Of REEP5 Depletion By AAV9 In The Mouse Heart
M Di Paola, C Reitz, U Kuzmanov, K Jia, A Teng, A Gramolini
Circulation Research 133 (Suppl_1), AP1027-AP1027, 2023
2023
A Fluorescence-Based Assay of Membrane Potential for High-Throughput Functional Study of Two Endogenous Ion Channels in Two Epithelial Cell Lines
S Xia, M Di Paola, NL Jones, CE Bear
JoVE (Journal of Visualized Experiments), e63528, 2022
2022
Reduced Cardiac Tmem65 In Mouse Hearts Results In Intercalated Disc Defects And Eventual Dilated Cardiomyopathy With Cardiac Fibrosis
AC Teng, L Gu, M Di Paola, Z Williams, A Au, N Callaghan, FH Zadeh, ...
CIRCULATION RESEARCH 129, 2021
2021
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