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Javier Apfeld
Javier Apfeld
Associate Professor, Northeastern University
Verified email at northeastern.edu - Homepage
Title
Cited by
Cited by
Year
aph-1 and pen-2 are required for Notch pathway signaling, γ-secretase cleavage of βAPP, and presenilin protein accumulation
R Francis, G McGrath, J Zhang, DA Ruddy, M Sym, J Apfeld, M Nicoll, ...
Developmental cell 3 (1), 85-97, 2002
11772002
Sirt1 regulates insulin secretion by repressing UCP2 in pancreatic β cells
L Bordone, MC Motta, F Picard, A Robinson, US Jhala, J Apfeld, ...
PLoS biology 4 (2), e31, 2006
9272006
The AMP-activated protein kinase AAK-2 links energy levels and insulin-like signals to lifespan in C. elegans
J Apfeld, G O'Connor, T McDonagh, PS DiStefano, R Curtis
Genes & development 18 (24), 3004-3009, 2004
8022004
Regulation of lifespan by sensory perception in Caenorhabditis elegans
J Apfeld, C Kenyon
Nature 402 (6763), 804-809, 1999
6961999
Regulation of life-span by germ-line stem cells in Caenorhabditis elegans
N Arantes-Oliveira, J Apfeld, A Dillin, C Kenyon
Science 295 (5554), 502-505, 2002
6002002
Cell nonautonomy of C. elegans daf-2 function in the regulation of diapause and life span
J Apfeld, C Kenyon
Cell 95 (2), 199-210, 1998
4681998
A microfabricated array of clamps for immobilizing and imaging C. elegans
SE Hulme, SS Shevkoplyas, J Apfeld, W Fontana, GM Whitesides
Lab on a Chip 7 (11), 1515-1523, 2007
2882007
The Caenorhabditis elegans Lifespan Machine
N Stroustrup, BE Ulmschneider, ZM Nash, IF López-Moyado, J Apfeld, ...
Nature methods 10 (7), 665-670, 2013
2732013
Lifespan-on-a-chip: microfluidic chambers for performing lifelong observation of C. elegans
SE Hulme, SS Shevkoplyas, AP McGuigan, J Apfeld, W Fontana, ...
Lab on a Chip 10 (5), 589-597, 2010
2612010
The temporal scaling of Caenorhabditis elegans ageing
N Stroustrup, WE Anthony, ZM Nash, V Gowda, A Gomez, ...
Nature 530 (7588), 103-107, 2016
1762016
What Can We Learn About Human Disease from the Nematode C. elegans?
J Apfeld, S Alper
Disease Gene Identification: Methods and Protocols, 53-75, 2018
1142018
An insulin-to-insulin regulatory network orchestrates phenotypic specificity in development and physiology
DA Fernandes de Abreu, A Caballero, P Fardel, N Stroustrup, Z Chen, ...
PLoS genetics 10 (3), e1004225, 2014
1102014
The Caenorhabditis elegans germ line regulates distinct signaling pathways to control lifespan and innate immunity
S Alper, MK McElwee, J Apfeld, B Lackford, JH Freedman, DA Schwartz
Journal of Biological Chemistry 285 (3), 1822-1828, 2010
852010
nanos is an evolutionarily conserved organizer of anterior-posterior polarity
D Curtis, J Apfeld, R Lehmann
Development 121 (6), 1899-1910, 1995
851995
Regulated spatial organization and sensitivity of cytosolic protein oxidation in Caenorhabditis elegans
C Romero-Aristizabal, DS Marks, W Fontana, J Apfeld
Nature communications 5 (1), 5020, 2014
372014
Contributions of orientation and hydrogen bonding to catalysis in Asn229 mutants of thymidylate synthase
JS Finer-Moore, L Liu, DL Birdsall, R Brem, J Apfeld, DV Santi, RM Stroud
Journal of molecular biology 276 (1), 113-129, 1998
261998
Correction: Sirt1 regulates insulin secretion by repressing UCP2 in pancreatic β cells
L Bordone, MC Motta, F Picard, A Robinson, US Jhala, J Apfeld, ...
Plos Biology 13 (12), e1002346, 2015
222015
Caenorhabditis elegans processes sensory information to choose between freeloading and self-defense strategies
JA Schiffer, FA Servello, WR Heath, FRG Amrit, SV Stumbur, M Eder, ...
Elife 9, e56186, 2020
212020
AMPK pathway components
J Apfeld, G O'connor
US Patent App. 11/145,471, 2006
182006
Age-Dependence and Aging-Dependence: Neuronal Loss and Lifespan in a C. elegans Model of Parkinson’s Disease
J Apfeld, W Fontana
Biology 7 (1), 1, 2017
142017
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