Affar El Bachir
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A DNA vector-based RNAi technology to suppress gene expression in mammalian cells
G Sui, C Soohoo, EB Affar, F Gay, Y Shi, WC Forrester, Y Shi
Proceedings of the National Academy of Sciences 99 (8), 5515-5520, 2002
Coordinated histone modifications mediated by a CtBP co-repressor complex
Y Shi, J Sawada, G Sui, EB Affar, JR Whetstine, F Lan, H Ogawa, ...
Nature 422 (6933), 735-738, 2003
Cleavage of automodified poly (ADP-ribose) polymerase during apoptosis: evidence for involvement of caspase-7
M Germain, EB Affar, D D'Amours, VM Dixit, GS Salvesen, GG Poirier
Journal of Biological Chemistry 274 (40), 28379-28384, 1999
Yin Yang 1 is a negative regulator of p53
G Sui, EB Affar, Y Shi, C Brignone, NR Wall, P Yin, M Donohoe, MP Luke, ...
Cell 117 (7), 859-872, 2004
Importance of poly (ADP-ribose) glycohydrolase in the control of poly (ADP-ribose) metabolism
L Davidovic, M Vodenicharov, EB Affar, GG Poirier
Experimental cell research 268 (1), 7-13, 2001
Tumor suppressor and deubiquitinase BAP1 promotes DNA double-strand break repair
H Yu, H Pak, I Hammond-Martel, M Ghram, A Rodrigue, S Daou, ...
Proceedings of the National Academy of Sciences 111 (1), 285-290, 2014
BAP1 regulates IP3R3-mediated Ca2+ flux to mitochondria suppressing cell transformation
A Bononi, C Giorgi, S Patergnani, D Larson, K Verbruggen, M Tanji, ...
Nature 546 (7659), 549-553, 2017
The ubiquitin carboxyl hydrolase BAP1 forms a ternary complex with YY1 and HCF-1 and is a critical regulator of gene expression
H Yu, N Mashtalir, S Daou, I Hammond-Martel, J Ross, G Sui, GW Hart, ...
Molecular and cellular biology 30 (21), 5071-5085, 2010
Selective silencing by RNAi of a dominant allele that causes amyotrophic lateral sclerosis
H Ding, DS Schwarz, A Keene, EB Affar, L Fenton, X Xia, Y Shi, ...
Aging cell 2 (4), 209-217, 2003
Essential dosage-dependent functions of the transcription factor yin yang 1 in late embryonic development and cell cycle progression
EB Affar, F Gay, Y Shi, H Liu, M Huarte, S Wu, T Collins, E Li, Y Shi
Molecular and Cellular Biology 26 (9), 3565-3581, 2006
Par-4 links dopamine signaling and depression
SK Park, MD Nguyen, A Fischer, MPS Luke, EB Affar, PB Dieffenbach, ...
Cell 122 (2), 275-287, 2005
Autodeubiquitination protects the tumor suppressor BAP1 from cytoplasmic sequestration mediated by the atypical ubiquitin ligase UBE2O
N Mashtalir, S Daou, H Barbour, NN Sen, J Gagnon, I Hammond-Martel, ...
Molecular cell 54 (3), 392-406, 2014
Caspase-3-mediated processing of poly (ADP-ribose) glycohydrolase during apoptosis
EB Affar, M Germain, E Winstall, M Vodenicharov, RG Shah, GS Salvesen, ...
Journal of Biological Chemistry 276 (4), 2935-2942, 2001
The BAP1/ASXL2 Histone H2A Deubiquitinase Complex Regulates Cell Proliferation and Is Disrupted in Cancer*♦
S Daou, I Hammond-Martel, N Mashtalir, H Barbour, J Gagnon, ...
Journal of Biological Chemistry 290 (48), 28643-28663, 2015
Roles of ubiquitin signaling in transcription regulation
I Hammond-Martel, H Yu, EB Affar
Cellular signalling 24 (2), 410-421, 2012
Regulation of activation-induced deaminase stability and antibody gene diversification by Hsp90
A Orthwein, AM Patenaude, EB Affar, A Lamarre, JC Young, JM Di Noia
Journal of Experimental Medicine 207 (12), 2751-2765, 2010
ATR kinase is required for global genomic nucleotide excision repair exclusively during S phase in human cells
Y Auclair, R Rouget, EB Affar, EA Drobetsky
Proceedings of the National Academy of Sciences 105 (46), 17896-17901, 2008
Crosstalk between O-GlcNAcylation and proteolytic cleavage regulates the host cell factor-1 maturation pathway
S Daou, N Mashtalir, I Hammond-Martel, H Pak, H Yu, G Sui, JL Vogel, ...
Proceedings of the National Academy of Sciences 108 (7), 2747-2752, 2011
Targeting of AMSH to endosomes is required for epidermal growth factor receptor degradation
YM Ma, E Boucrot, J VillÚn, EB Affar, SP Gygi, HG Göttlinger, ...
Journal of biological chemistry 282 (13), 9805-9812, 2007
Ikaros and GATA-1 combinatorial effect is required for silencing of human γ-globin genes
S Bottardi, J Ross, V Bourgoin, N Fotouhi-Ardakani, EB Affar, M Trudel, ...
Molecular and cellular biology 29 (6), 1526-1537, 2009
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