| Structure− activity relationship study of first selective inhibitor of excitatory amino acid transporter subtype 1: 2-amino-4-(4-methoxyphenyl)-7-(naphthalen-1-yl)-5-oxo-5, 6 … MN Erichsen, THV Huynh, B Abrahamsen, JF Bastlund, C Bundgaard, ... Journal of medicinal chemistry 53 (19), 7180-7191, 2010 | 132 | 2010 |
| Antiprotozoal Compounds from Asparagus africanus HA Oketch-Rabah, SF Dossaji, SB Christensen, K Frydenvang, ... Journal of natural products 60 (10), 1017-1022, 1997 | 128 | 1997 |
| GABA uptake inhibitors. Design, molecular pharmacology and therapeutic aspects P Krogsgaard-Larsen, B Frolund, K Frydenvang Current pharmaceutical design 6 (12), 1193-1209, 2000 | 115 | 2000 |
| UV-Guided Isolation of Alantrypinone, a Novel Penicillium Alkaloid TO Larsen, K Frydenvang, JC Frisvad, C Christophersen Journal of Natural Products 61 (9), 1154-1157, 1998 | 99 | 1998 |
| Lessons from more than 80 structures of the GluA2 ligand-binding domain in complex with agonists, antagonists and allosteric modulators J Pøhlsgaard, K Frydenvang, U Madsen, JS Kastrup Neuropharmacology 60 (1), 135-150, 2011 | 91 | 2011 |
| Psychrophilin A and Cycloaspeptide D, Novel Cyclic Peptides from the Psychrotolerant Fungus Penicillium ribeum PW Dalsgaard, TO Larsen, K Frydenvang, C Christophersen Journal of natural products 67 (5), 878-881, 2004 | 76 | 2004 |
| GABAA and GABAB receptor agonists, partial agonists, antagonists and modulators: design and therapeutic prospects P Krogsgaard-Larsen, B Fr, U Kristiansen, K Frydenvang, B Ebert European journal of pharmaceutical sciences 5 (6), 355-384, 1997 | 65 | 1997 |
| Full domain closure of the ligand-binding core of the ionotropic glutamate receptor iGluR5 induced by the high affinity agonist dysiherbaine and the functional antagonist 8, 9 … K Frydenvang, LL Lash, P Naur, PA Postila, DS Pickering, CM Smith, ... Journal of biological chemistry 284 (21), 14219-14229, 2009 | 63 | 2009 |
| Antiprotozoal properties of 16, 17-Dihydroxybrachycalyxolide from Vernonia brachycalyx HA Oketch-Rabah, SB Christensen, K Frydenvang, SF Dossaji, ... Planta Medica 64 (06), 559-562, 1998 | 62 | 1998 |
| Synthesis and antitumor effect in vitro and in vivo of substituted 1, 3-dihydroindole-2-ones MK Christensen, KD Erichsen, C Trojel-Hansen, J Tjørnelund, SJ Nielsen, ... Journal of medicinal chemistry 53 (19), 7140-7145, 2010 | 61 | 2010 |
| Rational Design, Synthesis, and Pharmacological Evaluation of 2-Azanorbornane-3-exo,5-endo-dicarboxylic Acid: A Novel Conformationally Restricted Glutamic … L Bunch, T Liljefors, JR Greenwood, K Frydenvang, H Bräuner-Osborne, ... The Journal of Organic Chemistry 68 (4), 1489-1495, 2003 | 60 | 2003 |
| Selective inhibitors of glial GABA uptake: synthesis, absolute stereochemistry, and pharmacology of the enantiomers of 3-hydroxy-4-amino-4, 5, 6, 7-tetrahydro-1, 2 … E Falch, J Perregaard, B Frølund, B Søkilde, A Buur, LM Hansen, ... Journal of medicinal chemistry 42 (26), 5402-5414, 1999 | 59 | 1999 |
| Lessons from crystal structures of kainate receptors S Møllerud, K Frydenvang, DS Pickering, JS Kastrup Neuropharmacology 112, 16-28, 2017 | 54 | 2017 |
| Chemoenzymatic Synthesis of New 2,4-syn-Functionalized (S)-Glutamate Analogues and Structure–Activity Relationship Studies at Ionotropic Glutamate … Z Assaf, AP Larsen, R Venskutonytė, L Han, B Abrahamsen, B Nielsen, ... Journal of medicinal chemistry 56 (4), 1614-1628, 2013 | 49 | 2013 |
| Correlation of aqueous solubility of salts of benzylamine with experimentally and theoretically derived parameters. A multivariate data analysis approach H Parshad, K Frydenvang, T Liljefors, CS Larsen International journal of pharmaceutics 237 (1-2), 193-207, 2002 | 49 | 2002 |
| 7-Phenoxy-Substituted 3,4-Dihydro-2H-1,2,4-benzothiadiazine 1,1-Dioxides as Positive Allosteric Modulators of α-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic … E Goffin, T Drapier, AP Larsen, P Geubelle, CP Ptak, S Laulumaa, ... Journal of medicinal chemistry 61 (1), 251-264, 2018 | 43 | 2018 |
| Synthesis, Pharmacological and Structural Characterization, and Thermodynamic Aspects of GluA2-Positive Allosteric Modulators with a 3,4-Dihydro-2H-1,2,4 … AB Nørholm, P Francotte, L Olsen, C Krintel, K Frydenvang, E Goffin, ... Journal of Medicinal Chemistry 56 (21), 8736-8745, 2013 | 43 | 2013 |
| Structure–activity relationships of a small-molecule inhibitor of the PDZ domain of PICK1 A Bach, N Stuhr-Hansen, TS Thorsen, N Bork, IS Moreira, K Frydenvang, ... Organic & biomolecular chemistry 8 (19), 4281-4288, 2010 | 43 | 2010 |
| Design, Synthesis, and Pharmacological Characterization of Novel Spirocyclic Quinuclidinyl‐Δ2‐Isoxazoline Derivatives as Potent and Selective Agonists of α7 … C Dallanoce, P Magrone, C Matera, F Frigerio, G Grazioso, M De Amici, ... ChemMedChem 6 (5), 889-903, 2011 | 39 | 2011 |
| Microwave-assisted ring-opening of activated aziridines with resin-bound amines F Crestey, M Witt, K Frydenvang, D Stærk, JW Jaroszewski, H Franzyk The Journal of Organic Chemistry 73 (9), 3566-3569, 2008 | 39 | 2008 |
