| The crystal structure of human Argonaute2 NT Schirle, IJ MacRae Science 336 (6084), 1037-1040, 2012 | 793 | 2012 |
| Structural basis for microRNA targeting NT Schirle, J Sheu-Gruttadauria, IJ MacRae Science 346 (6209), 608-613, 2014 | 591 | 2014 |
| A dynamic search process underlies microRNA targeting SD Chandradoss, NT Schirle, M Szczepaniak, IJ MacRae, C Joo Cell 162 (1), 96-107, 2015 | 253 | 2015 |
| The ER membrane protein complex interacts cotranslationally to enable biogenesis of multipass membrane proteins MJ Shurtleff, DN Itzhak, JA Hussmann, NT Schirle Oakdale, EA Costa, ... Elife 7, e37018, 2018 | 191 | 2018 |
| Structural basis for target-directed microRNA degradation J Sheu-Gruttadauria, P Pawlica, SM Klum, S Wang, TA Yario, ... Molecular cell 75 (6), 1243-1255. e7, 2019 | 189 | 2019 |
| RNA editing changes the lesion specificity for the DNA repair enzyme NEIL1 J Yeo, RA Goodman, NT Schirle, SS David, PA Beal Proceedings of the National Academy of Sciences 107 (48), 20715-20719, 2010 | 166 | 2010 |
| Structure of the 4-1BB/4-1BBL complex and distinct binding and functional properties of utomilumab and urelumab SM Chin, CR Kimberlin, Z Roe-Zurz, P Zhang, A Xu, S Liao-Chan, D Sen, ... Nature communications 9 (1), 4679, 2018 | 122 | 2018 |
| Water-mediated recognition of t1-adenosine anchors Argonaute2 to microRNA targets NT Schirle, J Sheu-Gruttadauria, SD Chandradoss, C Joo, IJ MacRae Elife 4, e07646, 2015 | 112 | 2015 |
| Structural analysis of human Argonaute-2 bound to a modified siRNA guide NT Schirle, GA Kinberger, HF Murray, WF Lima, TP Prakash, IJ MacRae Journal of the American Chemical Society 138 (28), 8694-8697, 2016 | 82 | 2016 |
| Structural and mechanistic basis of the EMC-dependent biogenesis of distinct transmembrane clients LE Miller-Vedam, B Bräuning, KD Popova, NT Schirle Oakdale, JL Bonnar, ... elife 9, e62611, 2020 | 71 | 2020 |
| Helix‐7 in Argonaute2 shapes the microRNA seed region for rapid target recognition SM Klum, SD Chandradoss, NT Schirle, C Joo, IJ MacRae The EMBO journal 37 (1), 75-88, 2018 | 68 | 2018 |
| Structure-guided control of siRNA off-target effects SR Suter, J Sheu-Gruttadauria, NT Schirle, R Valenzuela, AA Ball-Jones, ... Journal of the American Chemical Society 138 (28), 8667-8669, 2016 | 52 | 2016 |
| Screening helix-threading peptides for RNA binding using a thiazole orange displacement assay M Krishnamurthy, NT Schirle, PA Beal Bioorganic & medicinal chemistry 16 (19), 8914-8921, 2008 | 33 | 2008 |
| Selective inhibition of ADAR2-catalyzed editing of the serotonin 2c receptor pre-mRNA by a helix-threading peptide NT Schirle, RA Goodman, M Krishnamurthy, PA Beal Organic & Biomolecular Chemistry 8 (21), 4898-4904, 2010 | 32 | 2010 |
| Potent and Selective Inhibition of A-to-I RNA Editing with 2′-O-Methyl/Locked Nucleic Acid-Containing Antisense Oligoribonucleotides RA Mizrahi, NT Schirle, PA Beal ACS chemical biology 8 (4), 832-839, 2013 | 29 | 2013 |
| Structure and mechanism of Argonaute proteins NT Schirle, IJ MacRae The enzymes 32, 83-100, 2012 | 12 | 2012 |
| Structural insights into interactions between viral suppressor of RNA silencing protein p19 mutants and small RNA s DV Foss, NT Schirle, IJ MacRae, JP Pezacki FEBS Open bio 9 (6), 1042-1051, 2019 | 8 | 2019 |
| Structure of the 4-1BB/4-1BBL complex and distinct binding and functional properties of utomilumab and urelumab. Nat. Commun. 9, 4679 SM Chin, CR Kimberlin, Z Roe-Zurz, P Zhang, A Xu, S Liao-Chan, D Sen, ... | 5 | 2018 |
| Water-mediated recognition of t1-adenosine anchors Argonaute2 to microRNA targets-See more at: http://elifesciences. org/content/early/2015/09/11/eLife. 07646# sthash. CUHzGKUq … NT Schirle, J Sheu-Gruttadauria, SD Chandradoss, C Joo, IJ MacRae eLife 4 (09, 2015), 2016 | | 2016 |
| Mechanisms of microRNA‐Mediated Gene Silencing I Mac Rae, N Schirle, J Sheu‐Gruttadauria The FASEB Journal 29, 238.2, 2015 | | 2015 |
