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Michelle Kimple
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Decreased consumption of branched-chain amino acids improves metabolic health
L Fontana, NE Cummings, SIA Apelo, JC Neuman, I Kasza, BA Schmidt, ...
Cell reports 16 (2), 520-530, 2016
3992016
Overview of affinity tags for protein purification
ME Kimple, AL Brill, RL Pasker
Current protocols in protein science 73 (1), 9.9. 1-9.9. 23, 2013
3992013
Structural determinants for GoLoco-induced inhibition of nucleotide release by Gα subunits
RJ Kimple, ME Kimple, L Betts, J Sondek, DP Siderovski
Nature 416 (6883), 878-881, 2002
3032002
Restoration of metabolic health by decreased consumption of branched‐chain amino acids
NE Cummings, EM Williams, I Kasza, EN Konon, MD Schaid, BA Schmidt, ...
The Journal of physiology 596 (4), 623-645, 2018
2952018
Alternative rapamycin treatment regimens mitigate the impact of rapamycin on glucose homeostasis and the immune system
SI Arriola Apelo, JC Neuman, EL Baar, FA Syed, NE Cummings, HK Brar, ...
Aging cell 15 (1), 28-38, 2016
1782016
Involvement of a mitochondrial phosphatase in the regulation of ATP production and insulin secretion in pancreatic β cells
DJ Pagliarini, SE Wiley, ME Kimple, JR Dixon, P Kelly, CA Worby, ...
Molecular cell 19 (2), 197-207, 2005
1662005
Prostaglandin E2 receptor, EP3, is induced in diabetic islets and negatively regulates glucose-and hormone-stimulated insulin secretion
ME Kimple, MP Keller, MR Rabaglia, RL Pasker, JC Neuman, ...
Diabetes 62 (6), 1904-1912, 2013
1152013
Overview of affinity tags for protein purification
ME Kimple, J Sondek
Current protocols in protein science 36 (1), 9.9. 1-9.9. 19, 2004
1002004
Phenotypic characterization of MIP-CreERT1Lphi mice with transgene-driven islet expression of human growth hormone
D Oropeza, N Jouvet, L Budry, JE Campbell, K Bouyakdan, J Lacombe, ...
Diabetes 64 (11), 3798-3807, 2015
952015
Short-term methionine deprivation improves metabolic health via sexually dimorphic, mTORC1-independent mechanisms
D Yu, SE Yang, BR Miller, JA Wisinski, DS Sherman, JA Brinkman, ...
The FASEB Journal 32 (6), 3471, 2018
782018
Functional relevance of the disulfide‐linked complex of the N‐terminal PDZ domain of InaD with NorpA
ME Kimple, DP Siderovski, J Sondek
The EMBO Journal, 2001
752001
Inhibitory G proteins and their receptors: emerging therapeutic targets for obesity and diabetes
ME Kimple, JC Neuman, AK Linnemann, PJ Casey
Experimental & molecular medicine 46 (6), e102-e102, 2014
662014
Pancreatic β-cells from mice offset age-associated mitochondrial deficiency with reduced KATP channel activity
T Gregg, C Poudel, BA Schmidt, RS Dhillon, SM Sdao, NA Truchan, ...
Diabetes 65 (9), 2700-2710, 2016
652016
A method for mouse pancreatic islet isolation and intracellular cAMP determination
JC Neuman, NA Truchan, JW Joseph, ME Kimple
JoVE (Journal of Visualized Experiments), e50374, 2014
652014
Glucagon-like peptide-1 regulates cholecystokinin production in β-cells to protect from apoptosis
AK Linnemann, JC Neuman, TJ Battiola, JA Wisinski, ME Kimple, ...
Molecular endocrinology 29 (7), 978-987, 2015
612015
Opposing effects of prostaglandin E2 receptors EP3 and EP4 on mouse and human β-cell survival and proliferation
BA Carboneau, JA Allan, SE Townsend, ME Kimple, RM Breyer, ...
Molecular metabolism 6 (6), 548-559, 2017
512017
Gαz negatively regulates insulin secretion and glucose clearance
ME Kimple, JW Joseph, CL Bailey, PT Fueger, IA Hendry, CB Newgard, ...
Journal of biological chemistry 283 (8), 4560-4567, 2008
512008
Tcf19 is a novel islet factor necessary for proliferation and survival in the INS-1 β-cell line
KA Krautkramer, AK Linnemann, DA Fontaine, AL Whillock, TW Harris, ...
American Journal of Physiology-Endocrinology and Metabolism 305 (5), E600-E610, 2013
502013
A role for Gz in pancreatic islet β-cell biology
ME Kimple, AB Nixon, P Kelly, CL Bailey, KH Young, TA Fields, PJ Casey
Journal of Biological Chemistry 280 (36), 31708-31713, 2005
492005
Deletion of GαZ protein protects against diet-induced glucose intolerance via expansion of β-cell mass
ME Kimple, JB Moss, HK Brar, TC Rosa, NA Truchan, RL Pasker, ...
Journal of Biological Chemistry 287 (24), 20344-20355, 2012
462012
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