Massively parallel de novo protein design for targeted therapeutics A Chevalier, DA Silva, GJ Rocklin, DR Hicks, R Vergara, P Murapa, ... Nature 550 (7674), 74-79, 2017 | 417 | 2017 |
Functional convergence of oxylipin and abscisic acid pathways controls stomatal closure in response to drought T Savchenko, VA Kolla, CQ Wang, Z Nasafi, DR Hicks, B Phadungchob, ... Plant Physiology 164 (3), 1151-1160, 2014 | 277 | 2014 |
Scaffolding protein functional sites using deep learning J Wang, S Lisanza, D Juergens, D Tischer, JL Watson, KM Castro, ... Science 377 (6604), 387-394, 2022 | 233 | 2022 |
Human CTP synthase filament structure reveals the active enzyme conformation EM Lynch, DR Hicks, M Shepherd, JA Endrizzi, A Maker, JM Hansen, ... Nature structural & molecular biology 24 (6), 507-514, 2017 | 159 | 2017 |
A key general stress response motif is regulated non‐uniformly by CAMTA transcription factors G Benn, CQ Wang, DR Hicks, J Stein, C Guthrie, K Dehesh The Plant Journal 80 (1), 82-92, 2014 | 83 | 2014 |
The plastidial retrograde signal methyl erythritol cyclopyrophosphate is a regulator of salicylic acid and jasmonic acid crosstalk M Lemos, Y Xiao, M Bjornson, J Wang, D Hicks, A Souza, CQ Wang, ... Journal of Experimental Botany 67 (5), 1557-1566, 2016 | 55 | 2016 |
Supplementation with abscisic acid reduces malaria disease severity and parasite transmission EKK Glennon, LG Adams, DR Hicks, K Dehesh, S Luckhart The American journal of tropical medicine and hygiene 94 (6), 1266, 2016 | 32 | 2016 |
De novo design of modular peptide-binding proteins by superhelical matching K Wu, H Bai, YT Chang, R Redler, KE McNally, W Sheffler, TJ Brunette, ... Nature 616 (7957), 581-589, 2023 | 18 | 2023 |
De novo design of protein homodimers containing tunable symmetric protein pockets DR Hicks, MA Kennedy, KA Thompson, M DeWitt, B Coventry, A Kang, ... Proceedings of the National Academy of Sciences 119 (30), e2113400119, 2022 | 12 | 2022 |
ORA47 is a transcriptional regulator of a general stress response hub L Zeng, H Chen, Y Wang, D Hicks, H Ke, J Pruneda‐Paz, K Dehesh The Plant Journal 110 (2), 562-571, 2022 | 6 | 2022 |
Hallucination of closed repeat proteins containing central pockets L An, DR Hicks, D Zorine, J Dauparas, BIM Wicky, LF Milles, A Courbet, ... Nature Structural & Molecular Biology 30 (11), 1755-1760, 2023 | 5 | 2023 |
Modulation of FGF pathway signaling and vascular differentiation using designed oligomeric assemblies NI Edman, RL Redler, A Phal, T Schlichthaerle, SR Srivatsan, A Etemadi, ... bioRxiv, 2023 | 4 | 2023 |
De novo design of diverse small molecule binders and sensors using Shape Complementary Pseudocycles L An, M Said, L Tran, S Majumder, I Goreshnik, GR Lee, D Juergens, ... bioRxiv, 2023 | 3 | 2023 |
Design of Diverse Asymmetric Pockets in De Novo Homo-oligomeric Proteins SR Gerben, AJ Borst, DR Hicks, I Moczygemba, D Feldman, B Coventry, ... Biochemistry 62 (2), 358-368, 2023 | 3 | 2023 |
Scaffolding protein functional sites using deep learning D Baker, J Wang, R Ragotte, L Milles, JL Watson, D Juergens, S Lisanza, ... US Patent App. 18/339,519, 2023 | | 2023 |
In vivo selection of synthetic nucleocapsids for tissue targeting A Olshefsky, H Benasutti, M Sylvestre, GL Butterfield, GJ Rocklin, ... Proceedings of the National Academy of Sciences 120 (46), e2306129120, 2023 | | 2023 |
De novo design of buttressed loops for sculpting protein functions H Jiang, KM Jude, K Wu, J Fallas, G Ueda, TJ Brunette, D Hicks, H Pyles, ... bioRxiv, 2023 | | 2023 |
De novo design of energy transfer proteins housing excitonically coupled chlorophyll special pairs N Ennist, S Wang, M Kennedy, M Curti, G Sutherland, C Vasilev, R Redler, ... Research Square, 2023 | | 2023 |
De novo designed protein homodimers containing tunable symmetric pockets D Baker, D Hicks US Patent App. 17/938,752, 2023 | | 2023 |
De novodesign of modular peptide binding proteins by superhelical matching (preprint) K Wu, H Bai, YT Chang, R Redler, K McNally, W Sheffler, TJ Brunette, ... | | 2022 |