Matthew H. Larson
Matthew H. Larson
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Repurposing CRISPR as an RNA-guided platform for sequence-specific control of gene expression
LS Qi, MH Larson, LA Gilbert, JA Doudna, JS Weissman, AP Arkin, ...
Cell 152 (5), 1173-1183, 2013
CRISPR-mediated modular RNA-guided regulation of transcription in eukaryotes
LA Gilbert, MH Larson, L Morsut, Z Liu, GA Brar, SE Torres, ...
Cell 154 (2), 442-451, 2013
CRISPR interference (CRISPRi) for sequence-specific control of gene expression
MH Larson, LA Gilbert, X Wang, WA Lim, JS Weissman, LS Qi
Nature protocols 8 (11), 2180-2196, 2013
A comprehensive, CRISPR-based functional analysis of essential genes in bacteria
JM Peters, A Colavin, H Shi, TL Czarny, MH Larson, S Wong, JS Hawkins, ...
Cell 165 (6), 1493-1506, 2016
A pause sequence enriched at translation start sites drives transcription dynamics in vivo
MH Larson, RA Mooney, JM Peters, T Windgassen, D Nayak, CA Gross, ...
Science 344 (6187), 1042-1047, 2014
Rqc2p and 60S ribosomal subunits mediate mRNA-independent elongation of nascent chains
PS Shen, J Park, Y Qin, X Li, K Parsawar, MH Larson, J Cox, Y Cheng, ...
Science 347 (6217), 75-78, 2015
Applied force reveals mechanistic and energetic details of transcription termination
MH Larson, WJ Greenleaf, R Landick, SM Block
Cell 132 (6), 971-982, 2008
Trigger loop dynamics mediate the balance between the transcriptional fidelity and speed of RNA polymerase II
MH Larson, J Zhou, CD Kaplan, M Palangat, RD Kornberg, R Landick, ...
Proceedings of the National Academy of Sciences 109 (17), 6555-6560, 2012
Single-molecule studies of RNA polymerase: one singular sensation, every little step it takes
MH Larson, R Landick, SM Block
Molecular cell 41 (3), 249-262, 2011
Pulling on the nascent RNA during transcription does not alter kinetics of elongation or ubiquitous pausing
RV Dalal, MH Larson, KC Neuman, J Gelles, R Landick, SM Block
Molecular cell 23 (2), 231-239, 2006
Ultrafast excited-state dynamics of RNA and DNA C tracts
B Cohen, MH Larson, B Kohler
Chemical physics 350 (1-3), 165-174, 2008
Efficient reconstitution of transcription elongation complexes for single-molecule studies of eukaryotic RNA polymerase II
M Palangat, M Larson, X Hu, A Gnatt, S Block, R Landick
Transcription 3 (3), 146-153, 2012
Structure of semiconductor device and method for manufacturing the same
H Ryu, JH Ahn
US Patent 6,548,862, 2003
Molecule by molecule, the physics and chemistry of life: SMB 2007
SM Block, MH Larson, WJ Greenleaf, KM Herbert, NR Guydosh, ...
Nature chemical biology 3 (4), 193-197, 2007
The National Dental Practice-Based Research Network Adult Anterior Open Bite Study: Treatment recommendations and their association with patient and practitioner characteristics
G Huang, C Baltuck, E Funkhouser, HFC Wang, L Todoki, S Finkleman, ...
American Journal of Orthodontics and Dentofacial Orthopedics 156 (3), 312-325, 2019
Methods for tagging and amplifying rna template molecules for preparing sequencing libraries
M Larson
US Patent App. 15/839,386, 2018
Power maps in finite groups
M Larson
arXiv preprint arXiv:1707.06696, 2017
Alignment-free filtering for cfNA fusion fragments
X Yang, Y Saito, A Rao, HJ Kim, P Singh, E Scott, M Larson, W Pan, ...
Bioinformatics 35 (14), i225-i232, 2019
The Circulating Cell-free Genome Atlas (CCGA) study: size selection of cell-free DNA (cfDNA) fragments
D Filippova, MH Larson, MC Maher, R Calef, M Pimentel, Y Zhou, ...
J Clin Oncol 37, 2019
Single Molecule Studies Reveal the Mechanism and Energetics of Transcriptional Termination
SM Block, MH Larson, WJ Greenleaf, R Landick
The FASEB Journal 22, 399.1-399.1, 2008
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