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Yanbo Wang
Yanbo Wang
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Year
Real-time observation of DNA target interrogation and product release by the RNA-guided endonuclease CRISPR Cpf1 (Cas12a)
D Singh, J Mallon, A Poddar, Y Wang, R Tippana, O Yang, S Bailey, T Ha
Proceedings of the National Academy of Sciences 115 (21), 5444-5449, 2018
1652018
Mechanisms of improved specificity of engineered Cas9s revealed by single-molecule FRET analysis
D Singh, Y Wang, J Mallon, O Yang, J Fei, A Poddar, D Ceylan, S Bailey, ...
Nature structural & molecular biology 25 (4), 347-354, 2018
1112018
Mimicking co-transcriptional RNA folding using a superhelicase
B Hua, S Panja, S Woodson, T Ha
Biophysical Journal 114 (3), 433a-434a, 2018
462018
Single molecule analysis of effects of non-canonical guide RNAs and specificity-enhancing mutations on Cas9-induced DNA unwinding
IC Okafor, D Singh, Y Wang, M Jung, H Wang, J Mallon, S Bailey, JK Lee, ...
Nucleic acids research 47 (22), 11880-11888, 2019
382019
Genome oligopaint via local denaturation fluorescence in situ hybridization
Y Wang, WT Cottle, H Wang, XA Feng, J Mallon, M Gavrilov, S Bailey, ...
Molecular cell 81 (7), 1566-1577. e8, 2021
242021
Real-time observation of Cas9 postcatalytic domain motions
Y Wang, J Mallon, H Wang, D Singh, M Hyun Jo, B Hua, S Bailey, T Ha
Proceedings of the National Academy of Sciences 118 (2), e2010650118, 2021
212021
The single-molecule centroid localization algorithm improves the accuracy of fluorescence binding assays
B Hua, Y Wang, S Park, KY Han, D Singh, JH Kim, W Cheng, T Ha
Biochemistry 57 (10), 1572-1576, 2018
92018
Achieving single nucleotide sensitivity in direct hybridization genome imaging
Y Wang, WT Cottle, H Wang, M Gavrilov, RS Zou, MT Pham, ...
Nature communications 13 (1), 7776, 2022
22022
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