Xiangguo Qiu
Xiangguo Qiu
Research scientist, NML-Canada
Verified email at
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Reversion of advanced Ebola virus disease in nonhuman primates with ZMapp
X Qiu, G Wong, J Audet, A Bello, L Fernando, JB Alimonti, ...
Nature 514 (7520), 47-53, 2014
Successful treatment of Ebola virus–infected cynomolgus macaques with monoclonal antibodies
X Qiu, J Audet, G Wong, S Pillet, A Bello, T Cabral, JE Strong, F Plummer, ...
Science translational medicine 4 (138), 138ra81-138ra81, 2012
Nanozyme-strip for rapid local diagnosis of Ebola
D Duan, K Fan, D Zhang, S Tan, M Liang, Y Liu, J Zhang, P Zhang, W Liu, ...
Biosensors and Bioelectronics 74, 134-141, 2015
Molecular determinants of human neutralizing antibodies isolated from a patient infected with Zika virus
Q Wang, H Yang, X Liu, L Dai, T Ma, J Qi, G Wong, R Peng, S Liu, J Li, ...
Science translational medicine 8 (369), 369ra179-369ra179, 2016
Structures of protective antibodies reveal sites of vulnerability on Ebola virus
CD Murin, ML Fusco, ZA Bornholdt, X Qiu, GG Olinger, L Zeitlin, ...
Proceedings of the National Academy of Sciences 111 (48), 17182-17187, 2014
A role for Fc function in therapeutic monoclonal antibody-mediated protection against Ebola virus
BM Gunn, WH Yu, MM Karim, JM Brannan, AS Herbert, AZ Wec, ...
Cell host & microbe 24 (2), 221-233. e5, 2018
Systematic analysis of monoclonal antibodies against Ebola virus GP defines features that contribute to protection
EO Saphire, SL Schendel, ML Fusco, K Gangavarapu, BM Gunn, AZ Wec, ...
Cell 174 (4), 938-952. e13, 2018
Immune parameters correlate with protection against ebola virus infection in rodents and nonhuman primates
G Wong, JS Richardson, S Pillet, A Patel, X Qiu, J Alimonti, J Hogan, ...
Science translational medicine 4 (158), 158ra146-158ra146, 2012
Mucosal Immunization of Cynomolgus Macaques with the VSVΔG/Z EBOVGP Vaccine Stimulates Strong Ebola GP-Specific Immune Responses
X Qiu, L Fernando, JB Alimonti, PL Melito, F Feldmann, D Dick, U Ströher, ...
PloS one 4 (5), e5547, 2009
Characterization of Zaire ebolavirus glycoprotein-specific monoclonal antibodies
X Qiu, JB Alimonti, PL Melito, L Fernando, U Ströher, SM Jones
Clinical immunology 141 (2), 218-227, 2011
mAbs and Ad-vectored IFN-α therapy rescue Ebola-infected nonhuman primates when administered after the detection of viremia and symptoms
X Qiu, G Wong, L Fernando, J Audet, A Bello, J Strong, JB Alimonti, ...
Science translational medicine 5 (207), 207ra143-207ra143, 2013
Dlx1, Dlx2, Pax6, Brn3b, and Chx10 homeobox gene expression defines the retinal ganglion and inner nuclear layers of the developing and adult mouse retina
J De Melo, X Qiu, G Du, L Cristante, DD Eisenstat
Journal of Comparative Neurology 461 (2), 187-204, 2003
Antibodies from a human survivor define sites of vulnerability for broad protection against ebolaviruses
AZ Wec, AS Herbert, CD Murin, EK Nyakatura, DM Abelson, JM Fels, ...
Cell 169 (5), 878-890. e15, 2017
Characterization of host immune responses in Ebola virus infections
G Wong, GP Kobinger, X Qiu
Expert review of clinical immunology 10 (6), 781-790, 2014
Assessment of a vesicular stomatitis virus-based vaccine by useof the mouse model of Ebola virus hemorrhagic fever.
FH Jones SM, Stroher U, Fernando L, Qiu X, Alimonti J, Melito P, Bray M ...
J Infect Dis, 2007
Sustained protection against Ebola virus infection following treatment of infected nonhuman primates with ZMAb
X Qiu, J Audet, G Wong, L Fernando, A Bello, S Pillet, JB Alimonti, ...
Scientific reports 3 (1), 3365, 2013
Emetine inhibits Zika and Ebola virus infections through two molecular mechanisms: inhibiting viral replication and decreasing viral entry.
Cell Discov 4 (31), doi: 10.1038/s41421-018-0034-1, 2018
Dual-signal readout nanospheres for rapid point-of-care detection of ebola virus glycoprotein
J Hu, YZ Jiang, LL Wu, Z Wu, Y Bi, G Wong, X Qiu, J Chen, DW Pang, ...
Analytical chemistry 89 (24), 13105-13111, 2017
The multiple roles of sGP in Ebola pathogenesis
MA de La Vega, G Wong, GP Kobinger, X Qiu
Viral immunology 28 (1), 3-9, 2015
Ebola viral load at diagnosis associates with patient outcome and outbreak evolution
MA de La Vega, G Caleo, J Audet, X Qiu, RA Kozak, JI Brooks, S Kern, ...
The Journal of clinical investigation 125 (12), 4421-4428, 2015
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