| Strain prioritization and genome mining for enediyne natural products X Yan, H Ge, T Huang, Hindra, D Yang, Q Teng, I Crnovčić, X Li, ... MBio 7 (6), 10.1128/mbio. 02104-16, 2016 | 95 | 2016 |
| The Actinomycin Biosynthetic Gene Cluster of Streptomyces chrysomallus: a Genetic Hall of Mirrors for Synthesis of a Molecule with Mirror Symmetry U Keller, M Lang, I Crnovcic, F Pfennig, F Schauwecker Journal of bacteriology 192 (10), 2583-2595, 2010 | 95 | 2010 |
| Genome Mining of Micromonospora yangpuensis DSM 45577 as a Producer of an Anthraquinone-Fused Enediyne X Yan, JJ Chen, A Adhikari, D Yang, I Crnovcic, N Wang, CY Chang, ... Organic Letters 19 (22), 6192-6195, 2017 | 61 | 2017 |
| Comparative studies of the biosynthetic gene clusters for anthraquinone-fused enediynes shedding light into the tailoring steps of tiancimycin biosynthesis X Yan, JJ Chen, A Adhikari, CN Teijaro, H Ge, I Crnovcic, CY Chang, ... Organic Letters 20 (18), 5918-5921, 2018 | 39 | 2018 |
| Aromatic C-Methyltransferases with Antipodal Stereoselectivity for Structurally Diverse Phenolic Amino Acids Catalyze the Methylation Step in the Biosynthesis of … I Crnovcic, R Süssmuth, U Keller Biochemistry 49 (45), 9698-9705, 2010 | 26 | 2010 |
| Resistance to enediyne antitumor antibiotics by sequestration CY Chang, X Yan, I Crnovcic, T Annaval, C Chang, B Nocek, JD Rudolf, ... Cell chemical biology 25 (9), 1075-1085. e4, 2018 | 23 | 2018 |
| Biochemical and structural characterization of TtnD, a prenylated FMN-dependent decarboxylase from the tautomycetin biosynthetic pathway T Annaval, L Han, JD Rudolf, G Xie, D Yang, CY Chang, M Ma, I Crnovcic, ... ACS Chemical Biology 13 (9), 2728-2738, 2018 | 23 | 2018 |
| Occurrence and biosynthesis of C-demethylactinomycins in actinomycin-producing Streptomyces chrysomallus and Streptomyces parvulus I Crnovčić, J Vater, U Keller The Journal of Antibiotics 66 (4), 211-218, 2013 | 21 | 2013 |
| Characterization of TnmH as an O-Methyltransferase Revealing Insights into Tiancimycin Biosynthesis and Enabling a Biocatalytic Strategy To Prepare Antibody … A Adhikari, CN Teijaro, X Yan, CY Chang, C Gui, YC Liu, I Crnovcic, ... Journal of medicinal chemistry 63 (15), 8432-8441, 2020 | 19 | 2020 |
| Genome Mining of Streptomyces mobaraensis DSM40847 as a Bleomycin Producer Providing a Biotechnology Platform To Engineer Designer Bleomycin Analogues Hindra, D Yang, Q Teng, LB Dong, I Crnovcic, T Huang, H Ge, B Shen Organic letters 19 (6), 1386-1389, 2017 | 19 | 2017 |
| Activities of recombinant human bleomycin hydrolase on bleomycins and engineered analogues revealing new opportunities to overcome bleomycin-induced pulmonary toxicity I Crnovcic, F Gan, D Yang, LB Dong, PG Schultz, B Shen Bioorganic & Medicinal Chemistry Letters 28 (16), 2670-2674, 2018 | 15 | 2018 |
| Discovery of alternative producers of the enediyne antitumor antibiotic C-1027 with high titers X Yan, Hindra, H Ge, D Yang, T Huang, I Crnovcic, CY Chang, SM Fang, ... Journal of natural products 81 (3), 594-599, 2018 | 14 | 2018 |
| Genetic interrelations in the actinomycin biosynthetic gene clusters of Streptomyces antibioticus IMRU 3720 and Streptomyces chrysomallus ATCC11523 … I Crnovčić, C Rückert, S Semsary, M Lang, J Kalinowski, U Keller Advances and Applications in Bioinformatics and Chemistry, 29-46, 2017 | 14 | 2017 |
| Ketonization of Proline Residues in the Peptide Chains of Actinomycins by a 4‐Oxoproline Synthase S Semsary, I Crnovčić, R Driller, J Vater, B Loll, U Keller ChemBioChem 19 (7), 706-715, 2018 | 11 | 2018 |
| Engineered production of cancer targeting peptide (CTP)-containing C-1027 in Streptomyces globisporus and biological evaluation W Li, X Li, T Huang, Q Teng, I Crnovcic, C Rader, B Shen Bioorganic & medicinal chemistry 24 (17), 3887-3892, 2016 | 11 | 2016 |
| Biosynthetic rivalry of o-aminophenol-carboxylic acids initiates production of hemi-actinomycins in Streptomyces antibioticus I Crnovčić, S Semsary, J Vater, U Keller RSC Advances 4 (10), 5065-5074, 2014 | 11 | 2014 |
| Cytochrome P450 hydroxylase TnmL catalyzing sequential hydroxylation with an additional proofreading activity in tiancimycin biosynthesis T Annaval, CN Teijaro, A Adhikari, X Yan, JJ Chen, I Crnovcic, D Yang, ... ACS chemical biology 16 (7), 1172-1178, 2021 | 10 | 2021 |
| Crystal structure of SgcJ, an NTF2-like superfamily protein involved in biosynthesis of the nine-membered enediyne antitumor antibiotic C-1027 T Huang, CY Chang, JR Lohman, JD Rudolf, Y Kim, C Chang, D Yang, ... The Journal of antibiotics 69 (10), 731-740, 2016 | 9 | 2016 |
| PokMT1 from the Polyketomycin Biosynthetic Machinery of Streptomyces diastatochromogenes Tü6028 Belongs to the Emerging Family of C-Methyltransferases … X Guo, I Crnovcic, CY Chang, J Luo, JR Lohman, M Papinski, A Bechthold, ... Biochemistry 57 (6), 1003-1011, 2018 | 8 | 2018 |
| Strain prioritization and genome mining for enediyne natural products. mBio 7 (6) X Yan, H Ge, T Huang, YD Hindra, Q Teng, I Crnovcic, X Li, JD Rudolf, ... | 8 | 2016 |
Ben ShenThe Scripps Research InstituteVerified email at scripps.edu
