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Michael A. Skinnider
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Confronting false discoveries in single-cell differential expression
JW Squair, M Gautier, C Kathe, MA Anderson, ND James, TH Hutson, ...
Nature Communications 12, 5692, 2021
5712021
PRISM 3: expanded prediction of natural product chemical structures from microbial genomes
MA Skinnider, NJ Merwin, CW Johnston, NA Magarvey
Nucleic acids research 45 (W1), W49-W54, 2017
3592017
Genomes to natural products Prediction informatics for secondary metabolomes (PRISM)
MA Skinnider, CA Dejong, PN Rees, CW Johnston, H Li, ALH Webster, ...
Nucleic acids research 43 (20), 9645-9662, 2015
3292015
Comprehensive prediction of secondary metabolite structure and biological activity from microbial genome sequences
MA Skinnider, CW Johnston, M Gunabalasingam, NJ Merwin, ...
Nature Communications 11 (1), 1-9, 2020
2712020
Genomic charting of ribosomally synthesized natural product chemical space facilitates targeted mining
MA Skinnider*, CW Johnston*, RE Edgar, CA Dejong, NJ Merwin, ...
Proceedings of the National Academy of Sciences 113 (42), E6343-E6351, 2016
1722016
The neurons that restore walking after paralysis
C Kathe*, MA Skinnider*, TH Hutson*, N Regazzi, M Gautier, ...
Nature 611 (7936), 540-547, 2022
1642022
Polyketide and nonribosomal peptide retro-biosynthesis and global gene cluster matching
CA Dejong*, GM Chen*, H Li*, CW Johnston, MR Edwards, PN Rees, ...
Nature chemical biology 12 (12), 1007-1014, 2016
1562016
An automated Genomes-to-Natural Products platform (GNP) for the discovery of modular natural products
CW Johnston*, MA Skinnider*, MA Wyatt, X Li, MRM Ranieri, L Yang, ...
Nature communications 6, 8421, 2015
1442015
Cell type prioritization in single-cell data
MA Skinnider*, JW Squair*, C Kathe, MA Anderson, M Gautier, ...
Nature Biotechnology 39 (1), 30-34, 2021
1412021
Evaluating measures of association for single-cell transcriptomics
MA Skinnider, JW Squair, LJ Foster
Nature methods 16 (5), 381-386, 2019
1322019
DeepRiPP integrates multiomics data to automate discovery of novel ribosomally synthesized natural products
NJ Merwin*, WK Mousa*, CA Dejong, MA Skinnider, MJ Cannon, H Li, ...
Proceedings of the National Academy of Sciences 117 (1), 371-380, 2020
1272020
Artificial intelligence for natural product drug discovery
MW Mullowney, KR Duncan, SS Elsayed, N Garg, JJJ van der Hooft, ...
Nature Reviews Drug Discovery 22 (11), 895-916, 2023
1192023
Assembly and clustering of natural antibiotics guides target identification
CW Johnston, MA Skinnider, CA Dejong, PN Rees, GM Chen, CG Walker, ...
Nature chemical biology 12 (4), 233-239, 2016
1122016
Chemical language models enable navigation in sparsely populated chemical space
MA Skinnider, RG Stacey, DS Wishart, LJ Foster
Nature Machine Intelligence 3 (9), 759-770, 2021
1062021
An atlas of protein-protein interactions across mouse tissues
MA Skinnider*, NE Scott*, A Prudova, CH Kerr, N Stoynov, RG Stacey, ...
Cell 184, 4073-4089, 2021
982021
A rapid and accurate approach for prediction of interactomes from co-elution data (PrInCE)
RG Stacey, MA Skinnider, NE Scott, LJ Foster
BMC Bioinformatics 18 (1), 457, 2017
652017
A deep generative model enables automated structure elucidation of novel psychoactive substances
MA Skinnider, F Wang, D Pasin, R Greiner, LJ Foster, PW Dalsgaard, ...
Nature Machine Intelligence 3, 973-984, 2021
552021
Recovery of walking after paralysis by regenerating characterized neurons to their natural target region
JW Squair*, M Milano*, A de Coucy, M Gautier, MA Skinnider, ND James, ...
Science 381 (6664), 1338-1345, 2023
542023
Meta-analysis defines principles for the design and analysis of co-fractionation mass spectrometry experiments
MA Skinnider, LJ Foster
Nature Methods 18 (7), 806-815, 2021
492021
Comparative analysis of chemical similarity methods for modular natural products with a hypothetical structure enumeration algorithm
MA Skinnider, CA Dejong, BC Franczak, PD McNicholas, NA Magarvey
Journal of Cheminformatics 9 (1), 46, 2017
492017
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Articles 1–20