Confronting false discoveries in single-cell differential expression JW Squair, M Gautier, C Kathe, MA Anderson, ND James, TH Hutson, ... Nature Communications 12, 5692, 2021 | 571 | 2021 |
PRISM 3: expanded prediction of natural product chemical structures from microbial genomes MA Skinnider, NJ Merwin, CW Johnston, NA Magarvey Nucleic acids research 45 (W1), W49-W54, 2017 | 359 | 2017 |
Genomes to natural products Prediction informatics for secondary metabolomes (PRISM) MA Skinnider, CA Dejong, PN Rees, CW Johnston, H Li, ALH Webster, ... Nucleic acids research 43 (20), 9645-9662, 2015 | 329 | 2015 |
Comprehensive prediction of secondary metabolite structure and biological activity from microbial genome sequences MA Skinnider, CW Johnston, M Gunabalasingam, NJ Merwin, ... Nature Communications 11 (1), 1-9, 2020 | 271 | 2020 |
Genomic charting of ribosomally synthesized natural product chemical space facilitates targeted mining MA Skinnider*, CW Johnston*, RE Edgar, CA Dejong, NJ Merwin, ... Proceedings of the National Academy of Sciences 113 (42), E6343-E6351, 2016 | 172 | 2016 |
The neurons that restore walking after paralysis C Kathe*, MA Skinnider*, TH Hutson*, N Regazzi, M Gautier, ... Nature 611 (7936), 540-547, 2022 | 164 | 2022 |
Polyketide and nonribosomal peptide retro-biosynthesis and global gene cluster matching CA Dejong*, GM Chen*, H Li*, CW Johnston, MR Edwards, PN Rees, ... Nature chemical biology 12 (12), 1007-1014, 2016 | 156 | 2016 |
An automated Genomes-to-Natural Products platform (GNP) for the discovery of modular natural products CW Johnston*, MA Skinnider*, MA Wyatt, X Li, MRM Ranieri, L Yang, ... Nature communications 6, 8421, 2015 | 144 | 2015 |
Cell type prioritization in single-cell data MA Skinnider*, JW Squair*, C Kathe, MA Anderson, M Gautier, ... Nature Biotechnology 39 (1), 30-34, 2021 | 141 | 2021 |
Evaluating measures of association for single-cell transcriptomics MA Skinnider, JW Squair, LJ Foster Nature methods 16 (5), 381-386, 2019 | 132 | 2019 |
DeepRiPP integrates multiomics data to automate discovery of novel ribosomally synthesized natural products NJ Merwin*, WK Mousa*, CA Dejong, MA Skinnider, MJ Cannon, H Li, ... Proceedings of the National Academy of Sciences 117 (1), 371-380, 2020 | 127 | 2020 |
Artificial intelligence for natural product drug discovery MW Mullowney, KR Duncan, SS Elsayed, N Garg, JJJ van der Hooft, ... Nature Reviews Drug Discovery 22 (11), 895-916, 2023 | 119 | 2023 |
Assembly and clustering of natural antibiotics guides target identification CW Johnston, MA Skinnider, CA Dejong, PN Rees, GM Chen, CG Walker, ... Nature chemical biology 12 (4), 233-239, 2016 | 112 | 2016 |
Chemical language models enable navigation in sparsely populated chemical space MA Skinnider, RG Stacey, DS Wishart, LJ Foster Nature Machine Intelligence 3 (9), 759-770, 2021 | 106 | 2021 |
An atlas of protein-protein interactions across mouse tissues MA Skinnider*, NE Scott*, A Prudova, CH Kerr, N Stoynov, RG Stacey, ... Cell 184, 4073-4089, 2021 | 98 | 2021 |
A rapid and accurate approach for prediction of interactomes from co-elution data (PrInCE) RG Stacey, MA Skinnider, NE Scott, LJ Foster BMC Bioinformatics 18 (1), 457, 2017 | 65 | 2017 |
A deep generative model enables automated structure elucidation of novel psychoactive substances MA Skinnider, F Wang, D Pasin, R Greiner, LJ Foster, PW Dalsgaard, ... Nature Machine Intelligence 3, 973-984, 2021 | 55 | 2021 |
Recovery of walking after paralysis by regenerating characterized neurons to their natural target region JW Squair*, M Milano*, A de Coucy, M Gautier, MA Skinnider, ND James, ... Science 381 (6664), 1338-1345, 2023 | 54 | 2023 |
Meta-analysis defines principles for the design and analysis of co-fractionation mass spectrometry experiments MA Skinnider, LJ Foster Nature Methods 18 (7), 806-815, 2021 | 49 | 2021 |
Comparative analysis of chemical similarity methods for modular natural products with a hypothetical structure enumeration algorithm MA Skinnider, CA Dejong, BC Franczak, PD McNicholas, NA Magarvey Journal of Cheminformatics 9 (1), 46, 2017 | 49 | 2017 |