Genomes to natural products Prediction informatics for secondary metabolomes (PRISM) MA Skinnider, CA Dejong, PN Rees, CW Johnston, H Li, ALH Webster, ... Nucleic acids research 43 (20), 9645-9662, 2015 | 198 | 2015 |
PRISM 3: expanded prediction of natural product chemical structures from microbial genomes MA Skinnider, NJ Merwin, CW Johnston, NA Magarvey Nucleic acids research 45 (W1), W49-W54, 2017 | 152 | 2017 |
Genomic charting of ribosomally synthesized natural product chemical space facilitates targeted mining MA Skinnider, CW Johnston, RE Edgar, CA Dejong, NJ Merwin, PN Rees, ... Proceedings of the National Academy of Sciences 113 (42), E6343-E6351, 2016 | 96 | 2016 |
Polyketide and nonribosomal peptide retro-biosynthesis and global gene cluster matching CA Dejong, GM Chen, H Li, CW Johnston, MR Edwards, PN Rees, ... Nature chemical biology 12 (12), 1007-1014, 2016 | 92 | 2016 |
An automated Genomes-to-Natural Products platform (GNP) for the discovery of modular natural products CW Johnston, MA Skinnider, MA Wyatt, X Li, MRM Ranieri, L Yang, ... Nature communications 6, 8421, 2015 | 91 | 2015 |
Assembly and clustering of natural antibiotics guides target identification CW Johnston, MA Skinnider, CA Dejong, PN Rees, GM Chen, CG Walker, ... Nature chemical biology 12 (4), 233-239, 2016 | 63 | 2016 |
Evaluating measures of association for single-cell transcriptomics MA Skinnider, JW Squair, LJ Foster Nature methods 16 (5), 381-386, 2019 | 33 | 2019 |
A rapid and accurate approach for prediction of interactomes from co-elution data (PrInCE) RG Stacey, MA Skinnider, NE Scott, LJ Foster BMC Bioinformatics 18 (1), 457, 2017 | 27 | 2017 |
DeepRiPP integrates multiomics data to automate discovery of novel ribosomally synthesized natural products NJ Merwin, WK Mousa, CA Dejong, MA Skinnider, MJ Cannon, H Li, ... Proceedings of the National Academy of Sciences 117 (1), 371-380, 2020 | 23 | 2020 |
The Canadian clinician-scientist training program must be reinstated DDW Twa, JW Squair, MA Skinnider, JX Ji The Journal of clinical investigation 125 (12), 4317-4319, 2015 | 20 | 2015 |
Genomic data integration systematically biases interactome mapping MA Skinnider, RG Stacey, LJ Foster PLoS computational biology 14 (10), e1006474, 2018 | 19 | 2018 |
Comparative analysis of chemical similarity methods for modular natural products with a hypothetical structure enumeration algorithm MA Skinnider, CA Dejong, BC Franczak, PD McNicholas, NA Magarvey Journal of Cheminformatics 9 (1), 46, 2017 | 17 | 2017 |
Global analysis of prokaryotic tRNA-derived cyclodipeptide biosynthesis MA Skinnider, CW Johnston, NJ Merwin, CA Dejong, NA Magarvey BMC Genomics 19 (1), 45, 2018 | 16 | 2018 |
Predictors of sustained research involvement among MD/PhD programme graduates MA Skinnider, DDW Twa, JW Squair, ND Rosenblum, CD Lukac, ... Medical education 52 (5), 536-545, 2018 | 15 | 2018 |
A Targeted Proteomics Analysis of Cerebrospinal Fluid after Acute Human Spinal Cord Injury F Streijger, MA Skinnider, JC Rogalski, R Balshaw, CP Shannon, ... Journal of Neurotrauma 34 (12), 2054-2068, 2017 | 15 | 2017 |
Characteristics and outcomes of Canadian MD/PhD program graduates: a cross-sectional survey MA Skinnider, JW Squair, DDW Twa, JX Ji, A Kuzyk, X Wang, ... CMAJ open 5 (2), E308-E314, 2017 | 15 | 2017 |
Statistical reanalysis of natural products reveals increasing chemical diversity MA Skinnider, NA Magarvey Proceedings of the National Academy of Sciences 114 (31), E6271-E6272, 2017 | 13 | 2017 |
Automated Identification of Depsipeptide Natural Products by an Informatic Search Algorithm MA Skinnider, CW Johnston, R Zvanych, NA Magarvey ChemBioChem 16 (2), 223-227, 2015 | 13 | 2015 |
Informatic search strategies to discover analogues and variants of natural product archetypes CW Johnston, AD Connaty, MA Skinnider, Y Li, A Grunwald, MA Wyatt, ... Journal of Industrial Microbiology and Biotechnology 43 (2-3), 293-298, 2016 | 10 | 2016 |
Exploration of Nonribosomal Peptide Families with an Automated Informatic Search Algorithm L Yang, A Ibrahim, CW Johnston, MA Skinnider, B Ma, NA Magarvey Chemistry & Biology 22 (9), 1259-1269, 2015 | 10 | 2015 |