Stephen R. Sprang
Stephen R. Sprang
Director, Center for Biomolecular Structure and Dynamics, The University of Montana
Verified email at
Cited by
Cited by
The structure of the G protein heterotrimer Giα1β1γ2
MA Wall, DE Coleman, E Lee, JA Ińiguez-Lluhi, BA Posner, AG Gilman, ...
Cell 83 (6), 1047-1058, 1995
G protein mechanisms: insights from structural analysis
SR Sprang
Annual review of biochemistry 66 (1), 639-678, 1997
Structures of Active Conformations of Giα1 and the Mechanism of GTP Hydrolysis
DE Coleman, AM Berghuis, E Lee, ME Linder, AG Gilman, SR Sprang
Science 265 (5177), 1405-1412, 1994
Crystal structure of the catalytic domains of adenylyl cyclase in a complex with Gsα· GTPγS
JJG Tesmer, RK Sunahara, AG Gilman, SR Sprang
Science 278 (5345), 1907-1916, 1997
Structure of RGS4 bound to AlF4−-activated Giα1: stabilization of the transition state for GTP hydrolysis
JJG Tesmer, DM Berman, AG Gilman, SR Sprang
Cell 89 (2), 251-261, 1997
Structure of the first C2 domain of synaptotagmin I: a novel Ca2+/phospholipid-binding fold
RB Sutton, BA Davletov, AM Berghuis, TC Sudhof, SR Sprang
Cell 80 (6), 929-938, 1995
The structure of tumor necrosis factor-α at 2.6 Ć resolution: Implications for receptor binding
MJ Eck, SR Sprang
Journal of Biological Chemistry 264 (29), 17595-17605, 1989
Affinity panning of a library of peptides displayed on bacteriophages reveals the binding specificity of BiP
S Blond-Elguindi, SE Cwirla, WJ Dower, RJ Lipshutz, SR Sprang, ...
Cell 75 (4), 717-728, 1993
Modularity in the TNF-receptor family
JH Naismith, SR Sprang
Trends in biochemical sciences 23 (2), 74-79, 1998
Crystal structure of the adenylyl cyclase activator Gsα
RK Sunahara, JJG Tesmer, AG Gilman, SR Sprang
Science 278 (5345), 1943-1947, 1997
Tertiary and quaternary structural changes in Giα1 induced by GTP hydrolysis
MB Mixon, E Lee, DE Coleman, AM Berghuis, AG Gilman, SR Sprang
Science 270 (5238), 954-960, 1995
Two-metal-ion catalysis in adenylyl cyclase
JJG Tesmer, RK Sunahara, RA Johnson, G Gosselin, AG Gilman, ...
Science 285 (5428), 756-760, 1999
Structural changes in glycogen phosphorylase induced by phosphorylation
SR Sprang, KR Acharya, EJ Goldsmith, DI Stuart, K Varvill, RJ Fletterick, ...
Nature 336 (6196), 215-221, 1988
Three-dimensional structure of human basic fibroblast growth factor, a structural homolog of interleukin 1 beta.
JD Zhang, LS Cousens, PJ Barr, SR Sprang
Proceedings of the National Academy of Sciences 88 (8), 3446-3450, 1991
Cytokine structural taxonomy and mechanisms of receptor engagement: Current opinion in structural biology 1993, 3: 815–827
SR Sprang, JF Bazan
Current opinion in structural biology 3 (6), 815-827, 1993
The three-dimensional structure of Asn102 mutant of trypsin: role of Asp102 in serine protease catalysis
S Sprang, T Standing, RJ Fletterick, RM Stroud, J Finer-Moore, NH Xuong, ...
Science 237 (4817), 905-909, 1987
Exchange of substrate and inhibitor specificities between adenylyl and guanylyl cyclases
RK Sunahara, A Beuve, JJG Tesmer, SR Sprang, DL Garbers, AG Gilman
Journal of Biological Chemistry 273 (26), 16332-16338, 1998
The structure of human lymphotoxin (tumor necrosis factor-beta) at 1.9-A resolution.
MJ Eck, M Ultsch, E Rinderknecht, AM De Vos, SR Sprang
Journal of Biological Chemistry 267 (4), 2119-2122, 1992
Crystallographic Evidence for Dimerization of Unliganded Tumor Necrosis Factor Receptor∗
JH Naismith, TQ Devine, BJ Brandhuber, SR Sprang
Journal of Biological Chemistry 270 (22), 13303-13307, 1995
Structure of the protein kinase Cβ phospholipid-binding C2 domain complexed with Ca2+
RB Sutton, SR Sprang
Structure 6 (11), 1395-1405, 1998
The system can't perform the operation now. Try again later.
Articles 1–20