Wen Xue
Wen Xue
the RNA Therapeutics Institute at the University of Massachusetts Medical School
Verified email at umassmed.edu - Homepage
TitleCited byYear
A microRNA component of the p53 tumour suppressor network
L He, X He, LP Lim, E De Stanchina, Z Xuan, Y Liang, W Xue, L Zender, ...
Nature 447 (7148), 1130-1134, 2007
27392007
Senescence and tumour clearance is triggered by p53 restoration in murine liver carcinomas
W Xue, L Zender, C Miething, RA Dickins, E Hernando, V Krizhanovsky, ...
Nature 445 (7128), 656-660, 2007
19212007
Identification and validation of oncogenes in liver cancer using an integrative oncogenomic approach
L Zender, MS Spector, W Xue, P Flemming, C Cordon-Cardo, J Silke, ...
Cell 125 (7), 1253-1267, 2006
10012006
Genome editing with Cas9 in adult mice corrects a disease mutation and phenotype
H Yin, W Xue, S Chen, RL Bogorad, E Benedetti, M Grompe, ...
Nature biotechnology 32 (6), 551-553, 2014
7412014
CRISPR-mediated direct mutation of cancer genes in the mouse liver
W Xue, S Chen, H Yin, T Tammela, T Papagiannakopoulos, NS Joshi, ...
Nature 514 (7522), 380-384, 2014
4872014
An oncogenomics-based in vivo RNAi screen identifies tumor suppressors in liver cancer
L Zender, W Xue, J Zuber, CP Semighini, A Krasnitz, B Ma, P Zender, ...
Cell 135 (5), 852-864, 2008
4302008
Therapeutic genome editing by combined viral and non-viral delivery of CRISPR system components in vivo
H Yin, CQ Song, JR Dorkin, LJ Zhu, Y Li, Q Wu, A Park, J Yang, S Suresh, ...
Nature biotechnology 34 (3), 328-333, 2016
4152016
KRAS and YAP1 converge to regulate EMT and tumor survival
DD Shao, W Xue, EB Krall, A Bhutkar, F Piccioni, X Wang, AC Schinzel, ...
Cell 158 (1), 171-184, 2014
3842014
Topoisomerase levels determine chemotherapy response in vitro and in vivo
DJ Burgess, J Doles, L Zender, W Xue, B Ma, WR McCombie, GJ Hannon, ...
Proceedings of the National Academy of Sciences 105 (26), 9053-9058, 2008
2612008
IAPs contain an evolutionarily conserved ubiquitin-binding domain that regulates NF-κB as well as cell survival and oncogenesis
M Gyrd-Hansen, M Darding, M Miasari, MM Santoro, L Zender, W Xue, ...
Nature cell biology 10 (11), 1309-1317, 2008
2402008
Rapid modelling of cooperating genetic events in cancer through somatic genome editing
FJ Sánchez-Rivera, T Papagiannakopoulos, R Romero, T Tammela, ...
Nature 516 (7531), 428-431, 2014
2272014
DLC1 is a chromosome 8p tumor suppressor whose loss promotes hepatocellular carcinoma
W Xue, A Krasnitz, R Lucito, R Sordella, L VanAelst, C Cordon-Cardo, ...
Genes & development 22 (11), 1439-1444, 2008
1762008
Adenovirus-mediated somatic genome editing of Pten by CRISPR/Cas9 in mouse liver in spite of Cas9-specific immune responses
D Wang, H Mou, S Li, Y Li, S Hough, K Tran, J Li, H Yin, DG Anderson, ...
Human gene therapy 26 (7), 432-442, 2015
1752015
Small RNA combination therapy for lung cancer
W Xue, JE Dahlman, T Tammela, OF Khan, S Sood, A Dave, W Cai, ...
Proceedings of the National Academy of Sciences 111 (34), E3553-E3561, 2014
1702014
Targeting cadherin‐17 inactivates Wnt signaling and inhibits tumor growth in liver carcinoma
LX Liu, NP Lee, VW Chan, W Xue, L Zender, C Zhang, M Mao, H Dai, ...
Hepatology 50 (5), 1453-1463, 2009
1182009
p53-dependent Nestin regulation links tumor suppression to cellular plasticity in liver cancer
DF Tschaharganeh, W Xue, DF Calvisi, M Evert, TV Michurina, LE Dow, ...
Cell 158 (3), 579-592, 2014
1072014
A cluster of cooperating tumor-suppressor gene candidates in chromosomal deletions
W Xue, T Kitzing, S Roessler, J Zuber, A Krasnitz, N Schultz, K Revill, ...
Proceedings of the National Academy of Sciences 109 (21), 8212-8217, 2012
1062012
Structure-guided chemical modification of guide RNA enables potent non-viral in vivo genome editing
H Yin, CQ Song, S Suresh, Q Wu, S Walsh, LH Rhym, E Mintzer, ...
Nature Biotechnology, nbt. 4005, 2017
982017
Response and resistance to NF-κB inhibitors in mouse models of lung adenocarcinoma
W Xue, E Meylan, TG Oliver, DM Feldser, MM Winslow, R Bronson, ...
Cancer discovery 1 (3), 236-247, 2011
972011
Caspase-2-mediated cleavage of Mdm2 creates a p53-induced positive feedback loop
TG Oliver, E Meylan, GP Chang, W Xue, JR Burke, TJ Humpton, ...
Molecular cell 43 (1), 57-71, 2011
952011
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Articles 1–20