Pedro Castelo-Branco
Pedro Castelo-Branco
Assistant Professor, Departemt of Biological Sciences and Medicine, University of Algarve
Verified email at - Homepage
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Driver mutations in histone H3. 3 and chromatin remodelling genes in paediatric glioblastoma
J Schwartzentruber, A Korshunov, XY Liu, DTW Jones, E Pfaff, K Jacob, ...
Nature 482 (7384), 226-231, 2012
Epigenomic alterations define lethal CIMP-positive ependymomas of infancy
SC Mack, H Witt, RM Piro, L Gu, S Zuyderduyn, AM Stütz, X Wang, ...
Nature 506 (7489), 445-450, 2014
Genomic analysis of diffuse intrinsic pontine gliomas identifies three molecular subgroups and recurrent activating ACVR1 mutations
P Buczkowicz, C Hoeman, P Rakopoulos, S Pajovic, L Letourneau, ...
Nature genetics 46 (5), 451-456, 2014
Subgroup-specific prognostic implications of TP53 mutation in medulloblastoma
N Zhukova, V Ramaswamy, M Remke, E Pfaff, DJH Shih, DC Martin, ...
Journal of Clinical Oncology 31 (23), 2927, 2013
Polypyrimidine tract binding protein modulates efficiency of polyadenylation
P Castelo-Branco, A Furger, M Wollerton, C Smith, A Moreira, N Proudfoot
Molecular and cellular biology 24 (10), 4174-4183, 2004
Methylation of the TERT promoter and risk stratification of childhood brain tumours: an integrative genomic and molecular study
P Castelo-Branco, S Choufani, S Mack, D Gallagher, C Zhang, T Lipman, ...
The lancet oncology 14 (6), 534-542, 2013
BRAF mutation and CDKN2A deletion define a clinically distinct subgroup of childhood secondary high-grade glioma
M Mistry, N Zhukova, D Merico, P Rakopoulos, R Krishnatry, M Shago, ...
Journal of clinical oncology 33 (9), 1015, 2015
Trichostatin A and oncolytic HSV combination therapy shows enhanced antitumoral and antiangiogenic effects
TC Liu, P Castelo-Branco, SD Rabkin, RL Martuza
Molecular Therapy 16 (6), 1041-1047, 2008
Mechanisms of human telomerase reverse transcriptase (h TERT) regulation: clinical impacts in cancer
R Lećo, JD Apolónio, D Lee, A Figueiredo, U Tabori, P Castelo-Branco
Journal of biomedical science 25 (1), 1-12, 2018
Neural tumor-initiating cells have distinct telomere maintenance and can be safely targeted for telomerase inhibition
P Castelo-Branco, C Zhang, T Lipman, M Fujitani, L Hansford, I Clarke, ...
Clinical Cancer Research 17 (1), 111-121, 2011
Monoallelic expression determines oncogenic progression and outcome in benign and malignant brain tumors
EJ Walker, C Zhang, P Castelo-Branco, C Hawkins, W Wilson, N Zhukova, ...
Cancer research 72 (3), 636-644, 2012
Serum miRNA predicts viable disease after chemotherapy in patients with testicular nonseminoma germ cell tumor
R Lećo, T van Agthoven, A Figueiredo, MAS Jewett, K Fadaak, J Sweet, ...
The Journal of urology 200 (1), 126-135, 2018
DNA hypermethylation within TERT promoter upregulates TERT expression in cancer
DD Lee, R Lećo, M Komosa, M Gallo, CH Zhang, T Lipman, M Remke, ...
The Journal of clinical investigation 129 (1), 223-229, 2019
Oncolytic herpes simplex virus vectors and taxanes synergize to promote killing of prostate cancer cells
BJ Passer, P Castelo-Branco, JS Buhrman, S Varghese, SD Rabkin, ...
Cancer gene therapy 16 (7), 551-560, 2009
Cancer stem cells in prostate cancer: Implications for targeted therapy
R Leao, C Domingos, A Figueiredo, R Hamilton, U Tabori, ...
Urologia internationalis 99 (2), 125-136, 2017
A cancer specific hypermethylation signature of the TERT promoter predicts biochemical relapse in prostate cancer: a retrospective cohort study
P Castelo-Branco, R Lećo, T Lipman, B Campbell, D Lee, A Price, ...
Oncotarget 7 (36), 57726, 2016
WNT activation by lithium abrogates TP53 mutation associated radiation resistance in medulloblastoma
N Zhukova, V Ramaswamy, M Remke, DC Martin, P Castelo-Branco, ...
Acta neuropathologica communications 2 (1), 174, 2014
Alternative lengthening of telomeres is enriched in, and impacts survival of TP53 mutant pediatric malignant brain tumors
J Mangerel, A Price, P Castelo-Branco, J Brzezinski, P Buczkowicz, ...
Acta neuropathologica 128 (6), 853-862, 2014
Oncolytic herpes simplex virus armed with xenogeneic homologue of prostatic acid phosphatase enhances antitumor efficacy in prostate cancer
P Castelo-Branco, BJ Passer, JS Buhrman, S Antoszczyk, M Marinelli, ...
Gene therapy 17 (6), 805-810, 2010
A pooled analysis of nivolumab for the treatment of advanced non-small-cell lung cancer and the role of PD-L1 as a predictive biomarker
PN Aguiar Jr, IL Santoro, H Tadokoro, G de Lima Lopes, BA Filardi, ...
Immunotherapy 8 (9), 1011-1019, 2016
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