| NUDT15 polymorphisms alter thiopurine metabolism and hematopoietic toxicity T Moriyama, R Nishii, V Perez-Andreu, W Yang, FA Klussmann, X Zhao, ... Nature genetics 48 (4), 367-373, 2016 | 463 | 2016 |
| Recurrent SPI1 (PU. 1) fusions in high-risk pediatric T cell acute lymphoblastic leukemia M Seki, S Kimura, T Isobe, K Yoshida, H Ueno, Y Nakajima-Takagi, ... Nature genetics 49 (8), 1274-1281, 2017 | 133 | 2017 |
| Integrated multiomics analysis of hepatoblastoma unravels its heterogeneity and provides novel druggable targets M Sekiguchi, M Seki, T Kawai, K Yoshida, M Yoshida, T Isobe, N Hoshino, ... NPJ precision oncology 4 (1), 20, 2020 | 47 | 2020 |
| Landscape of driver mutations and their clinical impacts in pediatric B-cell precursor acute lymphoblastic leukemia H Ueno, K Yoshida, Y Shiozawa, Y Nannya, Y Iijima-Yamashita, ... Blood advances 4 (20), 5165-5173, 2020 | 35 | 2020 |
| Identification of the genetic and clinical characteristics of neuroblastomas using genome-wide analysis K Uryu, R Nishimura, K Kataoka, Y Sato, A Nakazawa, H Suzuki, ... Oncotarget 8 (64), 107513, 2017 | 33 | 2017 |
| Integrated Molecular Characterization of the Lethal Pediatric Cancer Pancreatoblastoma T Isobe, M Seki, K Yoshida, M Sekiguchi, Y Shiozawa, Y Shiraishi, ... Cancer Research 78 (4), 865-876, 2018 | 27 | 2018 |
| DNA methylation-based classification reveals difference between pediatric T-cell acute lymphoblastic leukemia and normal thymocytes S Kimura, M Seki, T Kawai, H Goto, K Yoshida, T Isobe, M Sekiguchi, ... Leukemia 34 (4), 1163-1168, 2020 | 17 | 2020 |
| Integrated genetic and epigenetic analysis revealed heterogeneity of acute lymphoblastic leukemia in Down syndrome Y Kubota, K Uryu, T Ito, M Seki, T Kawai, T Isobe, T Kumagai, T Toki, ... Cancer science 110 (10), 3358-3367, 2019 | 17 | 2019 |
| Multi-omics analysis defines highly refractory RAS burdened immature subgroup of infant acute lymphoblastic leukemia T Isobe, M Takagi, A Sato-Otsubo, A Nishimura, G Nagae, C Yamagishi, ... Nature Communications 13 (1), 4501, 2022 | 15 | 2022 |
| Association of high-risk neuroblastoma classification based on expression profiles with differentiation and metabolism S Kimura, M Sekiguchi, K Watanabe, M Hiwatarai, M Seki, K Yoshida, ... Plos one 16 (1), e0245526, 2021 | 12 | 2021 |
| Comprehensive genetic analysis of pediatric germ cell tumors identifies potential drug targets Y Kubota, M Seki, T Kawai, T Isobe, M Yoshida, M Sekiguchi, S Kimura, ... Communications biology 3 (1), 544, 2020 | 12 | 2020 |
| Aggressive transformation of anaplastic large cell lymphoma with increased number of ALK-translocated chromosomes A Hoshino, K Nomura, T Hamashima, T Isobe, M Seki, M Hiwatari, ... International journal of hematology 101, 198-202, 2015 | 8 | 2015 |
| Genotoxic aldehyde stress prematurely ages hematopoietic stem cells in a p53-driven manner M Wang, LTL Brandt, X Wang, H Russell, E Mitchell, ... Molecular cell 83 (14), 2417-2433. e7, 2023 | 7 | 2023 |
| Pharmacological inhibition of METTL3 impacts specific haematopoietic lineages K Sturgess, E Yankova, MS Vijayabaskar, T Isobe, J Rak, I Kucinski, ... Leukemia 37 (10), 2133-2137, 2023 | 5 | 2023 |
| Identification of the ultrahigh-risk subgroup in neuroblastoma cases through DNA methylation analysis and its treatment exploiting cancer metabolism K Watanabe, S Kimura, M Seki, T Isobe, Y Kubota, M Sekiguchi, ... Oncogene 41 (46), 4994-5007, 2022 | 5 | 2022 |
| Oncogenic FGFR1 mutation and amplification in common cellular origin in a composite tumor with neuroblastoma and pheochromocytoma K Tasaka, H Ueno, K Yamasaki, T Okuno, T Isobe, S Kimura, K Umeda, ... Cancer Science 113 (4), 1535-1541, 2022 | 3 | 2022 |
| Alteration of the immune environment in bone marrow from children with recurrent B cell precursor acute lymphoblastic leukemia T Mikami, I Kato, JB Wing, H Ueno, K Tasaka, K Tanaka, H Kubota, ... Cancer Science 113 (1), 41-52, 2022 | 3 | 2022 |
| Mitotic perturbation is a key mechanism of action of decitabine in myeloid tumor treatment T Yabushita, T Chinen, A Nishiyama, S Asada, R Shimura, T Isobe, ... Cell Reports 42 (9), 2023 | 1 | 2023 |
| RNA-seq–based miRNA signature as an independent predictor of relapse in pediatric B-cell acute lymphoblastic leukemia H Kubota, H Ueno, K Tasaka, T Isobe, S Saida, I Kato, K Umeda, ... Blood Advances 8 (5), 1258-1271, 2024 | | 2024 |
| Myeloid/natural killer (NK) cell precursor acute leukemia as a distinct leukemia type A Nishimura, K Yokoyama, T Naruto, C Yamagishi, T Imamura, ... Science Advances 9 (50), eadj4407, 2023 | | 2023 |
