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Daniel J. Murphy
Daniel J. Murphy
University of Glasgow, School of Cancer Sciences
Verified email at glasgow.ac.uk - Homepage
Title
Cited by
Cited by
Year
Modelling Myc inhibition as a cancer therapy
L Soucek, J Whitfield, CP Martins, AJ Finch, DJ Murphy, NM Sodir, ...
Nature 455 (7213), 679-683, 2008
9502008
Distinct thresholds govern Myc's biological output in vivo
DJ Murphy, MR Junttila, L Pouyet, A Karnezis, K Shchors, DA Bui, ...
Cancer cell 14 (6), 447-457, 2008
5002008
Limited Mitochondrial Permeabilization Causes DNA Damage and Genomic Instability in the Absence of Cell Death
G Ichim, J Lopez, SU Ahmed, N Muthalagu, E Giampazolias, ME Delgado, ...
Molecular cell 57 (5), 860-872, 2015
3972015
Deregulated MYC expression induces dependence upon AMPK-related kinase 5
L Liu, J Ulbrich, J Müller, T Wüstefeld, L Aeberhard, TR Kress, ...
Nature 483 (7391), 608-612, 2012
2982012
MYC-dependent regulation and prognostic role of CIP2A in gastric cancer
A Khanna, C Böckelman, A Hemmes, MR Junttila, JP Wiksten, M Lundin, ...
JNCI: Journal of the National Cancer Institute 101 (11), 793-805, 2009
2662009
Developmental Regulation of Mitochondrial Apoptosis by c-Myc Governs Age-and Tissue-Specific Sensitivity to Cancer Therapeutics
KA Sarosiek, C Fraser, N Muthalagu, PD Bhola, W Chang, SK McBrayer, ...
Cancer Cell, 2016
2372016
Interleukin-6-and cyclic AMP-mediated signaling potentiates neuroendocrine differentiation of LNCaP prostate tumor cells
PD Deeble, DJ Murphy, SJ Parsons, ME Cox
Molecular and cellular biology 21 (24), 8471-8482, 2001
2372001
Oncogenic Myc Induces Expression of Glutamine Synthetase through Promoter Demethylation
AJ Bott, IC Peng, Y Fan, B Faubert, L Zhao, J Li, S Neidler, Y Sun, N Jaber, ...
Cell metabolism 22 (6), 1068-1077, 2015
2322015
Human SWI-SNF component BRG1 represses transcription of the c-fos gene
DJ Murphy, S Hardy, DA Engel
Molecular and cellular biology 19 (4), 2724-2733, 1999
1821999
Glutamine Anabolism Plays a Critical Role in Pancreatic Cancer by Coupling Carbon and Nitrogen Metabolism
AJ Bott, J Shen, C Tonelli, L Zhan, N Sivaram, YP Jiang, X Yu, V Bhatt, ...
Cell reports 29 (5), 1287-1298. e6, 2019
1332019
Repression of the type I interferon pathway underlies MYC & KRAS-dependent evasion of NK & B cells in pancreatic ductal adenocarcinoma
N Muthalagu, T Monteverde, X Raffo-Iraolagoitia, R Wiesheu, D Whyte, ...
Cancer Discovery, 2020
1152020
The ERBB network facilitates KRAS-driven lung tumorigenesis
B Kruspig, T Monteverde, S Neidler, A Hock, E Kerr, C Nixon, W Clark, ...
Science Translational Medicine 10 (446), eaao2565, 2018
1032018
MYC regulates ductal-neuroendocrine lineage plasticity in pancreatic ductal adenocarcinoma associated with poor outcome and chemoresistance
AS Farrell, AD Rhim, BC Sheppard, BL Allen-Petersen, C Pelz, ...
Nature Communications 8, 1728, 2017
932017
Evidence of cancer‐promoting roles for AMPK and related kinases
T Monteverde, N Muthalagu, J Port, DJ Murphy
The FEBS journal 282 (24), 4658-4671, 2015
912015
Apoptotic cell death in disease—Current understanding of the NCCD 2023
I Vitale, F Pietrocola, E Guilbaud, SA Aaronson, JM Abrams, D Adam, ...
Cell Death & Differentiation 30 (5), 1097-1154, 2023
832023
BIM is the primary mediator of MYC-induced apoptosis in multiple solid tissues
N Muthalagu, MR Junttila, KE Wiese, E Wolf, J Morton, B Bauer, GI Evan, ...
Cell reports 8 (5), 1347-1353, 2014
822014
A Neuronal Relay Mediates a Nutrient Responsive Gut/Fat Body Axis Regulating Energy Homeostasis in Adult Drosophila
JBC Alessandro Scopelliti, Christin Bauer, Yachuan Yu, Tong Zhang, Bjo ̈rn ...
Cell Metabolism 29, 2019
812019
CRISPR/Cas9-derived models of ovarian high grade serous carcinoma targeting Brca1, Pten and Nf1, and correlation with platinum sensitivity
JB Walton, M Farquharson, S Mason, J Port, B Kruspig, S Dowson, ...
Scientific Reports 7, 16827, 2017
812017
Defining the temporal requirements for Myc in the progression and maintenance of skin neoplasia
I Flores, DJ Murphy, LB Swigart, U Knies, GI Evan
Oncogene 23 (35), 5923-5930, 2004
782004
In vitro evidence for senescent multinucleated melanocytes as a source for tumor-initiating cells
C Leikam, AL Hufnagel, C Otto, DJ Murphy, B Mühling, S Kneitz, I Nanda, ...
Cell death & disease 6 (4), e1711, 2015
742015
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