| Loss of XIST in breast cancer activates MSN-c-Met and reprograms microglia via exosomal miRNA to promote brain metastasis F Xing, Y Liu, SY Wu, K Wu, S Sharma, YY Mo, J Feng, S Sanders, G Jin, ... Cancer research 78 (15), 4316-4330, 2018 | 262 | 2018 |
| Interactions between immunity, proliferation and molecular subtype in breast cancer prognosis S Nagalla, JW Chou, MC Willingham, J Ruiz, JP Vaughn, P Dubey, ... Genome biology 14, 1-18, 2013 | 204 | 2013 |
| Cavity-directed radiosurgery as adjuvant therapy after resection of a brain metastasis CA Jensen, MD Chan, TP McCoy, JD Bourland, AF DeGuzman, TL Ellis, ... Journal of neurosurgery 114 (6), 1585-1591, 2011 | 178 | 2011 |
| Initial SRS for patients with 5 to 15 brain metastases: results of a multi-institutional experience RT Hughes, AH Masters, ER McTyre, MK Farris, C Chung, BR Page, ... International Journal of Radiation Oncology* Biology* Physics 104 (5), 1091-1098, 2019 | 122 | 2019 |
| Repeat stereotactic radiosurgery as salvage therapy for locally recurrent brain metastases previously treated with radiosurgery WH McKay, ER McTyre, C Okoukoni, NK Alphonse-Sullivan, J Ruiz, ... Journal of neurosurgery 127 (1), 148-156, 2016 | 102 | 2016 |
| Brain metastasis velocity: a novel prognostic metric predictive of overall survival and freedom from whole-brain radiation therapy after distant brain failure following upfront … M Farris, ER McTyre, CK Cramer, R Hughes, DM Randolph II, ... International Journal of Radiation Oncology* Biology* Physics 98 (1), 131-141, 2017 | 100 | 2017 |
| Genetic heterogeneity in autosomal dominant essential tremor MJ Kovach, J Ruiz, K Kimonis, S Mueed, S Sinha, C Higgins, S Elble, ... Genetics in medicine 3 (3), 197-199, 2001 | 88 | 2001 |
| Analysis and visualization of gene expression microarray data in human cancer using self-organizing maps S Hautaniemi, O Yli-Harja, J Astola, P Kauraniemi, A Kallioniemi, M Wolf, ... Machine learning 52, 45-66, 2003 | 83 | 2003 |
| TGLI1 transcription factor mediates breast cancer brain metastasis via activating metastasis-initiating cancer stem cells and astrocytes in the tumor microenvironment SR Sirkisoon, RL Carpenter, T Rimkus, D Doheny, D Zhu, NR Aguayo, ... Oncogene 39 (1), 64-78, 2020 | 82 | 2020 |
| Immunotherapy is associated with improved survival and decreased neurologic death after SRS for brain metastases from lung and melanoma primaries CM Lanier, R Hughes, T Ahmed, M LeCompte, AH Masters, WJ Petty, ... Neuro-oncology practice 6 (5), 402-409, 2019 | 70 | 2019 |
| Predictors of neurologic and nonneurologic death in patients with brain metastasis initially treated with upfront stereotactic radiosurgery without whole-brain radiation therapy ER McTyre, AG Johnson, J Ruiz, S Isom, JT Lucas Jr, WH Hinson, ... Neuro-oncology 19 (4), 558-566, 2017 | 69 | 2017 |
| Nicotine promotes brain metastasis by polarizing microglia and suppressing innate immune function SY Wu, F Xing, S Sharma, K Wu, A Tyagi, Y Liu, D Zhao, RP Deshpande, ... Journal of Experimental Medicine 217 (8), e20191131, 2020 | 68 | 2020 |
| Pleural effusion aspirate for use in 3D lung cancer modeling and chemotherapy screening A Mazzocchi, M Devarasetty, S Herberg, WJ Petty, F Marini, L Miller, ... ACS biomaterials science & engineering 5 (4), 1937-1943, 2019 | 68 | 2019 |
| Staged stereotactic radiosurgery for large brain metastases: local control and clinical outcomes of a one-two punch technique A Dohm, ER McTyre, C Okoukoni, A Henson, CK Cramer, MC LeCompte, ... Neurosurgery 83 (1), 114-121, 2018 | 62 | 2018 |
| Myocardial infarction in thrombotic thrombocytopenic purpura: a single‐center experience and literature review AS Wahla, J Ruiz, N Noureddine, B Upadhya, DC Sane, J Owen European journal of haematology 81 (4), 311-316, 2008 | 62 | 2008 |
| Frailty assessment predicts toxicity during first cycle chemotherapy for advanced lung cancer regardless of chronologic age J Ruiz, AA Miller, JA Tooze, S Crane, WJ Petty, A Gajra, HD Klepin Journal of geriatric oncology 10 (1), 48-54, 2019 | 61 | 2019 |
| Impact of systemic targeted agents on the clinical outcomes of patients with brain metastases AG Johnson, J Ruiz, R Hughes, BR Page, S Isom, JT Lucas, ER McTyre, ... Oncotarget 6 (22), 18945, 2015 | 59 | 2015 |
| Low-grade gliomas J Ruiz, GJ Lesser Current treatment options in oncology 10, 231-242, 2009 | 59 | 2009 |
| Combined inhibition of JAK2-STAT3 and SMO-GLI1/tGLI1 pathways suppresses breast cancer stem cells, tumor growth, and metastasis D Doheny, S Sirkisoon, RL Carpenter, NR Aguayo, AT Regua, ... Oncogene 39 (42), 6589-6605, 2020 | 58 | 2020 |
| Long-term outcomes of a phase 2 trial of chemotherapy with consolidative radiation therapy for oligometastatic non-small cell lung cancer WJ Petty, JJ Urbanic, T Ahmed, R Hughes, B Levine, K Rusthoven, ... International Journal of Radiation Oncology* Biology* Physics 102 (3), 527-535, 2018 | 54 | 2018 |
Michael D. Chan, M.D.Professor of Radiation OncologyVerified email at wakehealth.edu
