Emad Alnemri
Emad Alnemri
Thomas Eakins Professor of Biochemistry and Molecular Biology, Thomas Jefferson University
Verified email at jefferson.edu - Homepage
Cited by
Cited by
Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1
DJ Klionsky, AK Abdel-Aziz, S Abdelfatah, M Abdellatif, A Abdoli, S Abel, ...
autophagy 17 (1), 1-382, 2021
Cytochrome c and dATP-dependent formation of Apaf-1/caspase-9 complex initiates an apoptotic protease cascade
P Li, D Nijhawan, I Budihardjo, SM Srinivasula, M Ahmad, ES Alnemri, ...
Cell 91 (4), 479-489, 1997
Classification of cell death: recommendations of the Nomenclature Committee on Cell Death 2009
G Kroemer, L Galluzzi, P Vandenabeele, J Abrams, ES Alnemri, ...
Cell death & differentiation 16 (1), 3-11, 2009
Human ICE/CED-3 protease nomenclature
ES Alnemri, DJ Livingston, DW Nicholson, G Salvesen, NA Thornberry, ...
Cell 87 (2), 171, 1996
Molecular definitions of cell death subroutines: recommendations of the Nomenclature Committee on Cell Death 2012
L Galluzzi, I Vitale, JM Abrams, ES Alnemri, EH Baehrecke, ...
Cell Death & Differentiation 19 (1), 107-120, 2012
Ordering the cytochrome c–initiated caspase cascade: hierarchical activation of caspases-2,-3,-6,-7,-8, and-10 in a caspase-9–dependent manner
EA Slee, MT Harte, RM Kluck, BB Wolf, CA Casiano, DD Newmeyer, ...
The Journal of cell biology 144 (2), 281-292, 1999
Cutting edge: NF-κB activating pattern recognition and cytokine receptors license NLRP3 inflammasome activation by regulating NLRP3 expression
FG Bauernfeind, G Horvath, A Stutz, ES Alnemri, K MacDonald, D Speert, ...
The Journal of Immunology 183 (2), 787-791, 2009
Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018
L Galluzzi, I Vitale, SA Aaronson, JM Abrams, D Adam, P Agostinis, ...
Cell Death & Differentiation 25 (3), 486-541, 2018
IAPs block apoptotic events induced by caspase‐8 and cytochrome c by direct inhibition of distinct caspases
QL Deveraux, N Roy, HR Stennicke, T Van Arsdale, Q Zhou, ...
The EMBO journal 17 (8), 2215-2223, 1998
AIM2 activates the inflammasome and cell death in response to cytoplasmic DNA
T Fernandes-Alnemri, JW Yu, P Datta, J Wu, ES Alnemri
Nature 458 (7237), 509-513, 2009
CPP32, a novel human apoptotic protein with homology to Caenorhabditis elegans cell death protein Ced-3 and mammalian interleukin-1 beta-converting enzyme.
T Fernandes-Alnemri, G Litwack, ES Alnemri
Journal of Biological Chemistry 269 (49), 30761-30764, 1994
Autoactivation of procaspase-9 by Apaf-1-mediated oligomerization
SM Srinivasula, M Ahmad, T Fernandes-Alnemri, ES Alnemri
Molecular cell 1 (7), 949-957, 1998
Structure-based discovery of an organic compound that binds Bcl-2 protein and induces apoptosis of tumor cells
JL Wang, D Liu, ZJ Zhang, S Shan, X Han, SM Srinivasula, CM Croce, ...
Proceedings of the National Academy of Sciences 97 (13), 7124-7129, 2000
A conserved XIAP-interaction motif in caspase-9 and Smac/DIABLO regulates caspase activity and apoptosis
SM Srinivasula, R Hegde, A Saleh, P Datta, E Shiozaki, J Chai, RA Lee, ...
Nature 410 (6824), 112-116, 2001
Negative regulation of the Apaf-1 apoptosome by Hsp70
A Saleh, SM Srinivasula, L Balkir, PD Robbins, ES Alnemri
Nature cell biology 2 (8), 476-483, 2000
In vitro activation of CPP32 and Mch3 by Mch4, a novel human apoptotic cysteine protease containing two FADD-like domains
T Fernandes-Alnemri, RC Armstrong, J Krebs, SM Srinivasula, L Wang, ...
Proceedings of the National Academy of Sciences 93 (15), 7464-7469, 1996
Identification of Omi/HtrA2 as a mitochondrial apoptotic serine protease that disrupts inhibitor of apoptosis protein-caspase interaction
R Hegde, SM Srinivasula, ZJ Zhang, R Wassell, R Mukattash, L Cilenti, ...
Journal of Biological Chemistry 277 (1), 432-438, 2002
The ketone metabolite β-hydroxybutyrate blocks NLRP3 inflammasome–mediated inflammatory disease
YH Youm, KY Nguyen, RW Grant, EL Goldberg, M Bodogai, D Kim, ...
Nature medicine 21 (3), 263-269, 2015
The pyroptosome: a supramolecular assembly of ASC dimers mediating inflammatory cell death via caspase-1 activation
T Fernandes-Alnemri, J Wu, JW Yu, P Datta, B Miller, W Jankowski, ...
Cell Death & Differentiation 14 (9), 1590-1604, 2007
Mechanism of XIAP-mediated inhibition of caspase-9
EN Shiozaki, J Chai, DJ Rigotti, SJ Riedl, P Li, SM Srinivasula, ...
Molecular cell 11 (2), 519-527, 2003
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