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Wenchang Zhou
Wenchang Zhou
Senior scientist, QuantX Biosciences
Verified email at quantxbio.com
Title
Cited by
Cited by
Year
High-resolution cryo-EM analysis of the yeast ATP synthase in a lipid membrane
AP Srivastava, M Luo, W Zhou, J Symersky, D Bai, MG Chambers, ...
Science 360 (6389), eaas9699, 2018
1872018
Coupling of remote alternating-access transport mechanisms for protons and substrates in the multidrug efflux pump AcrB
T Eicher, MA Seeger, C Anselmi, W Zhou, L Brandstätter, F Verrey, ...
Elife 3, e03145, 2014
1862014
Structure of human ATG9A, the only transmembrane protein of the core autophagy machinery
CM Guardia, XF Tan, T Lian, MS Rana, W Zhou, ET Christenson, ...
Cell reports 31 (13), 2020
1202020
Atomistic simulations indicate the c-subunit ring of the F1Fo ATP synthase is not the mitochondrial permeability transition pore
W Zhou, F Marinelli, C Nief, JD Faraldo-Gómez
Elife 6, e23781, 2017
852017
Bruton tyrosine kinase deficiency augments NLRP3 inflammasome activation and causes IL-1β–mediated colitis
L Mao, A Kitani, E Hiejima, K Montgomery-Recht, W Zhou, I Fuss, ...
The Journal of clinical investigation 130 (4), 1793-1807, 2020
722020
High-resolution structure and mechanism of an F/V-hybrid rotor ring in a Na+-coupled ATP synthase
D Matthies, W Zhou, AL Klyszejko, C Anselmi, Ö Yildiz, K Brandt, V Müller, ...
Nature communications 5, 2014
712014
Large-scale state-dependent membrane remodeling by a transporter protein
W Zhou, G Fiorin, C Anselmi, HA Karimi-Varzaneh, H Poblete, LR Forrest, ...
Elife 8, e50576, 2019
482019
TRPV1 pore turret dictates distinct DkTx and capsaicin gating
M Geron, R Kumar, W Zhou, JD Faraldo-Gómez, V Vásquez, A Priel
Proceedings of the National Academy of Sciences 115 (50), E11837-E11846, 2018
432018
Bedaquiline inhibits the yeast and human mitochondrial ATP synthases
M Luo, W Zhou, H Patel, AP Srivastava, J Symersky, MM Bonar, ...
Communications Biology 3 (1), 452, 2020
422020
Broadly conserved Na+-binding site in the N-lobe of prokaryotic multidrug MATE transporters
E Ficici, W Zhou, S Castellano, JD Faraldo-Gómez
Proceedings of the National Academy of Sciences 115 (27), E6172-E6181, 2018
312018
Predicting the structural basis of targeted protein degradation by integrating molecular dynamics simulations with structural mass spectrometry
T Dixon, D MacPherson, B Mostofian, T Dauzhenka, S Lotz, D McGee, ...
Nature communications 13 (1), 5884, 2022
282022
Calcineurin regulatory subunit B is a unique calcium sensor that regulates calcineurin in both calcium‐dependent and calcium‐independent manner
J Li, ZG Jia, WC Zhou, Q Wei
Proteins: Structure, Function, and Bioinformatics 77 (3), 612-623, 2009
242009
Characterization of essential domains in HSD17B13 for cellular localization and enzymatic activity
Y Ma, S Karki, PM Brown, DD Lin, MC Podszun, W Zhou, OV Belyaeva, ...
Journal of Lipid Research 61 (11), 1400-1409, 2020
192020
Asymmetric drug binding in an ATP-loaded inward-facing state of an ABC transporter
TM Thaker, S Mishra, W Zhou, M Mohan, Q Tang, JD Faraldo-Goméz, ...
Nature chemical biology 18 (2), 226-235, 2022
182022
DFT studies of the degradation mechanism of methyl mercury activated by a sulfur-rich ligand
X Li, RZ Liao, W Zhou, G Chen
Physical Chemistry Chemical Physics 12 (16), 3961-3971, 2010
162010
Differential ion dehydration energetics explains selectivity in the non-canonical lysosomal K+ channel TMEM175
SC Oh, F Marinelli, W Zhou, J Lee, HJ Choi, M Kim, JD Faraldo-Gómez, ...
eLife 11, e75122, 2022
112022
Conserved binding site in the N-lobe of prokaryotic MATE transporters suggests a role for Na+ in ion-coupled drug efflux
S Castellano, DP Claxton, E Ficici, T Kusakizako, R Stix, W Zhou, ...
Journal of Biological Chemistry 296, 2021
112021
Membrane plasticity facilitates recognition of the inhibitor oligomycin by the mitochondrial ATP synthase rotor
W Zhou, JD Faraldo-Gómez
Biochimica et Biophysica Acta (BBA)-Bioenergetics 1859 (9), 789-796, 2018
112018
The structure of human ATG9A and its interplay with the lipid bilayer
CM Guardia, ET Christenson, W Zhou, XF Tan, T Lian, JD Faraldo-Gómez, ...
Autophagy 16 (12), 2292-2293, 2020
72020
Mechanism of 4-aminopyridine inhibition of the lysosomal channel TMEM175
SC Oh, R Stix, W Zhou, JD Faraldo-Gómez, RK Hite
Proceedings of the National Academy of Sciences 119 (44), e2208882119, 2022
62022
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