| A Mec1-and Rad53-dependent checkpoint controls late-firing origins of DNA replication C Santocanale, JFX Diffley Nature 395 (6702), 615-618, 1998 | 812 | 1998 |
| An essential role for the Cdc6 protein in forming the pre-replicative complexes of budding yeast JH Cocker, S Piatti, C Santocanale, K Nasmyth, JFX Diffley Nature 379 (6561), 180-182, 1996 | 477 | 1996 |
| Identification of Mcm2 phosphorylation sites by S-phase-regulating kinases A Montagnoli, B Valsasina, D Brotherton, S Troiani, S Rainoldi, P Tenca, ... Journal of Biological Chemistry 281 (15), 10281-10290, 2006 | 253 | 2006 |
| A Cdc7 kinase inhibitor restricts initiation of DNA replication and has antitumor activity A Montagnoli, B Valsasina, V Croci, M Menichincheri, S Rainoldi, ... Nature chemical biology 4 (6), 357-365, 2008 | 243 | 2008 |
| ORC‐and Cdc6‐dependent complexes at active and inactive chromosomal replication origins in Saccharomyces cerevisiae. C Santocanale, JF Diffley The EMBO journal 15 (23), 6671-6679, 1996 | 236 | 1996 |
| Activation of dormant origins of DNA replication in budding yeast C Santocanale, K Sharma, JFX Diffley Genes & development 13 (18), 2360-2364, 1999 | 180 | 1999 |
| Cdc7 inhibition reveals a p53-dependent replication checkpoint that is defective in cancer cells A Montagnoli, P Tenca, F Sola, D Carpani, D Brotherton, C Albanese, ... Cancer research 64 (19), 7110-7116, 2004 | 179 | 2004 |
| Dbf4p, an essential S phase-promoting factor, is targeted for degradation by the anaphase-promoting complex M Godinho Ferreira, C Santocanale, LS Drury, JFX Diffley Molecular and cellular biology 20 (1), 242-248, 2000 | 176 | 2000 |
| Cdc7 kinase inhibitors: pyrrolopyridinones as potential antitumor agents. 1. Synthesis and structure–activity relationships E Vanotti, R Amici, A Bargiotti, J Berthelsen, R Bosotti, A Ciavolella, ... Journal of medicinal chemistry 51 (3), 487-501, 2008 | 127 | 2008 |
| Cdc7 is an active kinase in human cancer cells undergoing replication stress P Tenca, D Brotherton, A Montagnoli, S Rainoldi, C Albanese, ... Journal of biological chemistry 282 (1), 208-215, 2007 | 111 | 2007 |
| Drf1, a novel regulatory subunit for human Cdc7 kinase A Montagnoli, R Bosotti, F Villa, M Rialland, D Brotherton, C Mercurio, ... The EMBO Journal, 2002 | 106 | 2002 |
| Evidence for the progression through S-phase in the ectopic cell cycle re-entry of neurons in Alzheimer disease DJ Bonda, TA Evans, C Santocanale, JC Llosá, J Viňa, VP Bajic, ... Aging 1 (4), 382, 2009 | 100 | 2009 |
| Essential role of human CDT1 in DNA replication and chromatin licensing M Rialland, F Sola, C Santocanale Journal of cell science 115 (7), 1435-1440, 2002 | 98 | 2002 |
| The isolated 48,000-dalton subunit of yeast DNA primase is sufficient for RNA primer synthesis. C Santocanale, M Foiani, G Lucchini, P Plevani Journal of Biological Chemistry 268 (2), 1343-1348, 1993 | 93 | 1993 |
| Cdc7 kinase–a new target for drug development R Swords, D Mahalingam, M O’Dwyer, C Santocanale, K Kelly, J Carew, ... European journal of cancer 46 (1), 33-40, 2010 | 92 | 2010 |
| A Single Essential Gene, PRI2, Encodes the Large Subunit of DNA Primase in Saccharomyces cerevisiae M Foiani, C Santocanale, P Plevani, G Lucchini Molecular and cellular biology 9 (7), 3081-3087, 1989 | 92 | 1989 |
| Evidence for a Cdc6p-independent mitotic resetting event involving DNA polymerase α C Desdouets, C Santocanale, LS Drury, G Perkins, M Foiani, P Plevani, ... The EMBO Journal 17 (14), 4139-4146, 1998 | 86 | 1998 |
| First Cdc7 kinase inhibitors: pyrrolopyridinones as potent and orally active antitumor agents. 2. Lead discovery M Menichincheri, A Bargiotti, J Berthelsen, JA Bertrand, R Bossi, ... Journal of medicinal chemistry 52 (2), 293-307, 2009 | 84 | 2009 |
| DNA mediated chromatin pull-down for the study of chromatin replication AE Kliszczak, MD Rainey, B Harhen, FM Boisvert, C Santocanale Scientific reports 1 (1), 95, 2011 | 76 | 2011 |
| Mutations in the gene encoding the 34 kDa subunit of yeast replication protein A cause defective S phase progression C Santocanale, H Neecke, MP Longhese, G Lucchini, P Plevani Journal of molecular biology 254 (4), 595-607, 1995 | 75 | 1995 |
