| PaDEL‐descriptor: An open source software to calculate molecular descriptors and fingerprints CW Yap Journal of computational chemistry 32 (7), 1466-1474, 2011 | 2486 | 2011 |
| Social isolation, loneliness and their relationships with depressive symptoms: A population-based study L Ge, CW Yap, R Ong, BH Heng PloS one 12 (8), e0182145, 2017 | 387 | 2017 |
| Anticancer activity of thymoquinone in breast cancer cells: possible involvement of PPAR-γ pathway CC Woo, SY Loo, V Gee, CW Yap, G Sethi, AP Kumar, KHB Tan Biochemical pharmacology 82 (5), 464-475, 2011 | 300 | 2011 |
| Prediction of P-glycoprotein substrates by a support vector machine approach Y Xue, CW Yap, LZ Sun, ZW Cao, JF Wang, YZ Chen Journal of chemical information and computer sciences 44 (4), 1497-1505, 2004 | 227 | 2004 |
| Therapeutic targets: progress of their exploration and investigation of their characteristics CJ Zheng, LY Han, CW Yap, ZL Ji, ZW Cao, YZ Chen Pharmacological reviews 58 (2), 259-279, 2006 | 220 | 2006 |
| QSAR Modeling is not “Push a Button and Find a Correlation”: A Case Study of Toxicity of (Benzo‐) triazoles on Algae P Gramatica, S Cassani, PP Roy, S Kovarich, CW Yap, E Papa Molecular Informatics 31 (11‐12), 817-835, 2012 | 211 | 2012 |
| Effect of molecular descriptor feature selection in support vector machine classification of pharmacokinetic and toxicological properties of chemical agents Y Xue, ZR Li, CW Yap, LZ Sun, X Chen, YZ Chen Journal of chemical information and computer sciences 44 (5), 1630-1638, 2004 | 210 | 2004 |
| Prediction of cytochrome P450 3A4, 2D6, and 2C9 inhibitors and substrates by using support vector machines CW Yap, YZ Chen Journal of chemical information and modeling 45 (4), 982-992, 2005 | 199 | 2005 |
| Effect of selection of molecular descriptors on the prediction of blood-brain barrier penetrating and nonpenetrating agents by statistical learning methods H Li, CW Yap, CY Ung, Y Xue, ZW Cao, YZ Chen Journal of chemical information and modeling 45 (5), 1376-1384, 2005 | 194 | 2005 |
| Isorhamnetin Inhibits Proliferation and Invasion and Induces Apoptosis through the Modulation of Peroxisome Proliferator-activated Receptor γ Activation Pathway in Gastric Cancer L Ramachandran, KA Manu, MK Shanmugam, F Li, KS Siveen, S Vali, ... Journal of Biological Chemistry 287 (45), 38028-38040, 2012 | 151 | 2012 |
| Formulation development of transdermal dosage forms: Quantitative structure-activity relationship model for predicting activities of terpenes that enhance drug penetration … L Kang, CW Yap, PFC Lim, YZ Chen, PC Ho, YW Chan, GP Wong, ... Journal of controlled release 120 (3), 211-219, 2007 | 103 | 2007 |
| Prediction of genotoxicity of chemical compounds by statistical learning methods H Li, CY Ung, CW Yap, Y Xue, ZR Li, ZW Cao, YZ Chen Chemical research in toxicology 18 (6), 1071-1080, 2005 | 100 | 2005 |
| Mixed learning algorithms and features ensemble in hepatotoxicity prediction CY Liew, YC Lim, CW Yap Journal of computer-aided molecular design 25 (9), 855-871, 2011 | 98 | 2011 |
| Prediction of torsade-causing potential of drugs by support vector machine approach CW Yap, CZ Cai, Y Xue, YZ Chen Toxicological Sciences 79 (1), 170-177, 2004 | 98 | 2004 |
| Quantitative structure-pharmacokinetic relationships for drug clearance by using statistical learning methods CW Yap, ZR Li, YZ Chen Journal of Molecular Graphics and Modelling 24 (5), 383-395, 2006 | 97 | 2006 |
| Classification of a diverse set of tetrahymena pyriformis toxicity chemical compounds from molecular descriptors by statistical learning methods Y Xue, H Li, CY Ung, CW Yap, YZ Chen Chemical research in toxicology 19 (8), 1030-1039, 2006 | 96 | 2006 |
| Identification of Michael acceptor-centric pharmacophores with substituents that yield strong thioredoxin reductase inhibitory character correlated to antiproliferative activity FF Gan, KK Kaminska, H Yang, CY Liew, PC Leow, CL So, LL Tu Ngoc, ... Antioxidants & Redox Signaling, 2013 | 95 | 2013 |
| Machine learning approaches for predicting compounds that interact with therapeutic and ADMET related proteins H Li, CW Yap, CY Ung, Y Xue, ZR Li, LY Han, HH Lin, YZ Chen Journal of pharmaceutical sciences 96 (11), 2838-2860, 2007 | 90 | 2007 |
| In Silico Prediction of Pregnane X Receptor Activators by Machine Learning Approache CY Ung, H Li, CW Yap, YZ Chen Molecular pharmacology 71 (1), 158-168, 2007 | 89 | 2007 |
| Progress and problems in the exploration of therapeutic targets C Zheng, L Han, CW Yap, B Xie, Y Chen Drug discovery today 11 (9), 412-420, 2006 | 88 | 2006 |
