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Luigi Tortola
Luigi Tortola
Verified email at biol.ethz.ch
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Year
A dual role for autophagy in a murine model of lung cancer
S Rao, L Tortola, T Perlot, G Wirnsberger, M Novatchkova, R Nitsch, ...
Nature communications 5 (1), 3056, 2014
4342014
Psoriasiform dermatitis is driven by IL-36–mediated DC-keratinocyte crosstalk
L Tortola, E Rosenwald, B Abel, H Blumberg, M Schäfer, AJ Coyle, ...
The Journal of clinical investigation 122 (11), 3965-3976, 2012
4282012
The metabolite BH4 controls T cell proliferation in autoimmunity and cancer
SJF Cronin, C Seehus, A Weidinger, S Talbot, S Reissig, M Seifert, ...
Nature 563 (7732), 564-568, 2018
1992018
RANKL/RANK control Brca1 mutation-driven mammary tumors
V Sigl, K Owusu-Boaitey, PA Joshi, A Kavirayani, G Wirnsberger, ...
Cell research 26 (7), 761-774, 2016
1592016
The thioredoxin-1 system is essential for fueling DNA synthesis during T-cell metabolic reprogramming and proliferation
J Muri, S Heer, M Matsushita, L Pohlmeier, L Tortola, T Fuhrer, M Conrad, ...
Nature communications 9 (1), 1851, 2018
1082018
The kinase activity of Rip2 determines its stability and consequently Nod1-and Nod2-mediated immune responses
C Nembrini, J Kisielow, AT Shamshiev, L Tortola, AJ Coyle, M Kopf, ...
Journal of biological chemistry 284 (29), 19183-19188, 2009
1032009
Inhibition of CBLB protects from lethal Candida albicans sepsis
G Wirnsberger, F Zwolanek, T Asaoka, I Kozieradzki, L Tortola, ...
Nature medicine 22 (8), 915-923, 2016
982016
Apelin inhibition prevents resistance and metastasis associated with anti‐angiogenic therapy
I Uribesalgo, D Hoffmann, Y Zhang, A Kavirayani, J Lazovic, J Berta, ...
EMBO molecular medicine 11 (8), e9266, 2019
922019
Bhlhe40 and Bhlhe41 transcription factors regulate alveolar macrophage self‐renewal and identity
R Rauschmeier, C Gustafsson, A Reinhardt, N A‐Gonzalez, L Tortola, ...
The EMBO journal 38 (19), e101233, 2019
792019
The tumor suppressor Hace1 is a critical regulator of TNFR1-mediated cell fate
L Tortola, R Nitsch, MJM Bertrand, M Kogler, Y Redouane, I Kozieradzki, ...
Cell reports 15 (7), 1481-1492, 2016
682016
Jagunal homolog 1 is a critical regulator of neutrophil function in fungal host defense
G Wirnsberger, F Zwolanek, J Stadlmann, L Tortola, SW Liu, T Perlot, ...
Nature genetics 46 (9), 1028-1033, 2014
582014
High-dimensional T helper cell profiling reveals a broad diversity of stably committed effector states and uncovers interlineage relationships
L Tortola, A Jacobs, L Pohlmeier, FJ Obermair, F Ampenberger, ...
Immunity 53 (3), 597-613. e6, 2020
482020
RANK rewires energy homeostasis in lung cancer cells and drives primary lung cancer
S Rao, V Sigl, RA Wimmer, M Novatchkova, A Jais, G Wagner, ...
Genes & Development 31 (20), 2099-2112, 2017
382017
IL-21 promotes allergic airway inflammation by driving apoptosis of FoxP3+ regulatory T cells
L Tortola, H Pawelski, SS Sonar, F Ampenberger, M Kurrer, M Kopf
Journal of Allergy and Clinical Immunology 143 (6), 2178-2189. e5, 2019
352019
Evidence for the divergence of innate and adaptive T-cell precursors before commitment to the αβ and γδ lineages
J Kisielow, L Tortola, J Weber, K Karjalainen, M Kopf
Blood, The Journal of the American Society of Hematology 118 (25), 6591-6600, 2011
352011
IL-21 induces death of marginal zone B cells during chronic inflammation
L Tortola, K Yadava, MF Bachmann, C Müller, J Kisielow, M Kopf
Blood, The Journal of the American Society of Hematology 116 (24), 5200-5207, 2010
332010
Loss of Rnf31 and Vps4b sensitizes pancreatic cancer to T cell-mediated killing
N Frey, L Tortola, D Egli, S Janjuha, T Rothgangl, KF Marquart, ...
Nature communications 13 (1), 1804, 2022
272022
Adult T-cells impair neonatal cardiac regeneration
T Dolejsi, M Delgobo, T Schuetz, L Tortola, KG Heinze, U Hofmann, ...
European Heart Journal 43 (28), 2698-2709, 2022
252022
Cyclopentenone prostaglandins and structurally related oxidized lipid species instigate and share distinct pro-and anti-inflammatory pathways
J Muri, Q Feng, H Wolleb, A Shamshiev, C Ebner, L Tortola, P Broz, ...
Cell reports 30 (13), 4399-4417. e7, 2020
212020
HACE1 prevents lung carcinogenesis via inhibition of RAC-family GTPases
M Kogler, L Tortola, GL Negri, A Leopoldi, AM El-Naggar, S Mereiter, ...
Cancer research 80 (14), 3009-3022, 2020
192020
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