Status of GPCR modeling and docking as reflected by community-wide GPCR Dock 2010 assessment I Kufareva, M Rueda, V Katritch, RC Stevens, R Abagyan Structure 19 (8), 1108-1126, 2011 | 343 | 2011 |
Comparison of two highly-effective mRNA vaccines for COVID-19 during periods of Alpha and Delta variant prevalence A Puranik, PJ Lenehan, E Silvert, MJM Niesen, J Corchado-Garcia, ... MedRxiv, 2021 | 298 | 2021 |
FDA-authorized mRNA COVID-19 vaccines are effective per real-world evidence synthesized across a multi-state health system C Pawlowski, P Lenehan, A Puranik, V Agarwal, AJ Venkatakrishnan, ... Med 2 (8), 979-992. e8, 2021 | 220 | 2021 |
The role of conformational ensembles in ligand recognition in G-protein coupled receptors MJM Niesen, S Bhattacharya, N Vaidehi Journal of the American Chemical Society 133 (33), 13197-13204, 2011 | 88 | 2011 |
Omicron variant of SARS-CoV-2 harbors a unique insertion mutation of putative viral or human genomic origin AJ Venkatakrishnan, P Anand, P Lenehan, R Suratekar, B Raghunathan, ... OSF, 2021 | 69 | 2021 |
Forces on nascent polypeptides during membrane insertion and translocation via the Sec translocon MJM Niesen, A Müller-Lucks, R Hedman, G von Heijne, TF Miller Biophysical Journal 115 (10), 1885-1894, 2018 | 38 | 2018 |
COVID-19 vaccines dampen genomic diversity of SARS-CoV-2: Unvaccinated patients exhibit more antigenic mutational variance MJM Niesen, P Anand, E Silvert, R Suratekar, C Pawlowski, P Ghosh, ... MedRxiv, 2021.07. 01.21259833, 2021 | 33 | 2021 |
Water orientation and dynamics in the closed and open influenza B virus M2 proton channels MD Gelenter, VS Mandala, MJM Niesen, DA Sharon, AJ Dregni, ... Communications Biology 4 (1), 338, 2021 | 29 | 2021 |
Structurally detailed coarse-grained model for Sec-facilitated co-translational protein translocation and membrane integration MJM Niesen, CY Wang, RC Van Lehn, TF Miller III PLoS computational biology 13 (3), e1005427, 2017 | 28 | 2017 |
Surveillance of safety of 3 doses of COVID-19 mRNA vaccination using electronic health records MJM Niesen, C Pawlowski, JC O’Horo, DW Challener, E Silvert, ... JAMA network open 5 (4), e227038-e227038, 2022 | 27 | 2022 |
High diversity in Delta variant across countries revealed by genome‐wide analysis of SARS‐CoV‐2 beyond the Spike protein R Suratekar, P Ghosh, MJM Niesen, G Donadio, P Anand, ... Molecular systems biology 18 (2), e10673, 2022 | 27 | 2022 |
Critical analysis of the successes and failures of homology models of G protein‐coupled receptors S Bhattacharya, AR Lam, H Li, G Balaraman, MJM Niesen, N Vaidehi Proteins: Structure, Function, and Bioinformatics 81 (5), 729-739, 2013 | 27 | 2013 |
Comparative effectiveness of mRNA-1273 and BNT162b2 against symptomatic SARS-CoV-2 infection A Puranik, PJ Lenehan, E Silvert, MJM Niesen, J Corchado-Garcia, ... Med 3 (1), 28-41. e8, 2022 | 25 | 2022 |
Advanced techniques for constrained internal coordinate molecular dynamics JR Wagner, GS Balaraman, MJM Niesen, AB Larsen, A Jain, N Vaidehi Journal of computational chemistry 34 (11), 904-914, 2013 | 24 | 2013 |
Water dynamics around proteins: T-and R-states of hemoglobin and melittin M Pezzella, K El Hage, MJM Niesen, S Shin, AP Willard, M Meuwly, ... The Journal of Physical Chemistry B 124 (30), 6540-6554, 2020 | 21 | 2020 |
A link between integral membrane protein expression and simulated integration efficiency SS Marshall, MJM Niesen, A Müller, K Tiemann, SM Saladi, RP Galimidi, ... Cell Reports 16 (8), 2169-2177, 2016 | 21 | 2016 |
Durability analysis of the highly effective BNT162b2 vaccine against COVID-19 A Puranik, PJ Lenehan, JC O'Horo, C Pawlowski, MJM Niesen, A Virk, ... PNAS nexus 1 (3), pgac082, 2022 | 20 | 2022 |
Improving membrane protein expression by optimizing integration efficiency MJM Niesen, SS Marshall, TF Miller, WM Clemons Journal of Biological Chemistry 292 (47), 19537-19545, 2017 | 17 | 2017 |
Thermostabilization of the β1-Adrenergic Receptor Correlates with Increased Entropy of the Inactive State MJM Niesen, S Bhattacharya, R Grisshammer, CG Tate, N Vaidehi The Journal of Physical Chemistry B 117 (24), 7283-7291, 2013 | 17 | 2013 |
On the origins of omicron’s unique spike gene insertion AJ Venkatakrishnan, P Anand, PJ Lenehan, R Suratekar, B Raghunathan, ... Vaccines 10 (9), 1509, 2022 | 16 | 2022 |