A mechanism for regulation of the adhesion-associated protein tyrosine kinase pp125FAK A Richardson, JT Parsons Nature 380 (6574), 538-540, 1996 | 647 | 1996 |
Inhibition of cell spreading by expression of the C-terminal domain of focal adhesion kinase (FAK) is rescued by coexpression of Src or catalytically inactive FAK: a role for … A Richardson, RK Malik, JD Hildebrand, JT Parsons Molecular and cellular biology 17 (12), 6906-6914, 1997 | 400 | 1997 |
Signal transduction through integrins: a central role for focal adhesion kinase? A Richardson, JT Parsons Bioessays 17 (3), 229-236, 1995 | 369 | 1995 |
Molecular cloning, expression and characterization of the human serine/threonine kinase Akt‐3 S Masure, B Haefner, JJ Wesselink, E Hoefnagel, E Mortier, P Verhasselt, ... European journal of biochemistry 265 (1), 353-360, 1999 | 213 | 1999 |
Structure and function of inositol triphosphate receptors CW Taylor, A Richardson Pharmacology & therapeutics 51 (1), 97-137, 1991 | 203 | 1991 |
Focal adhesion kinase: structure and signalling JT Parsons, MD Schaller, J Hildebrand, TH Leu, A Richardson, C Otey Journal of Cell Science 1994 (Supplement_18), 109-113, 1994 | 147 | 1994 |
Effects of Ca2+ chelators on purified inositol 1, 4, 5-trisphosphate (InsP3) receptors and InsP3-stimulated Ca2+ mobilization A Richardson, CW Taylor Journal of Biological Chemistry 268 (16), 11528-11533, 1993 | 137 | 1993 |
The Bcl-2/Bcl-XL Family Inhibitor ABT-737 Sensitizes Ovarian Cancer Cells to Carboplatin J Witham, MR Valenti, AK De-Haven-Brandon, S Vidot, SA Eccles, ... Clinical cancer research 13 (23), 7191-7198, 2007 | 133 | 2007 |
The identification of p130cas-binding proteins and their role in cellular transformation. MR Burnham, MT Harte, A Richardson, JT Parsons, AH Bouton Oncogene 12 (11), 2467-2472, 1996 | 129 | 1996 |
Serine Phosphorylation of Focal Adhesion Kinase in Interphase and Mitosis: A Possible Role in Modulating Binding to p130Cas A Ma, A Richardson, EM Schaefer, JT Parsons Molecular biology of the cell 12 (1), 1-12, 2001 | 119 | 2001 |
Autotaxin delays apoptosis induced by carboplatin in ovarian cancer cells S Vidot, J Witham, R Agarwal, S Greenhough, HS Bamrah, GJ Tigyi, ... Cellular signalling 22 (6), 926-935, 2010 | 101 | 2010 |
Drug resistance in ovarian cancer: the emerging importance of gene transcription and spatio-temporal regulation of resistance A Richardson, SB Kaye Drug Resistance Updates 8 (5), 311-321, 2005 | 82 | 2005 |
Pharmacological inhibition of the Bcl-2 family of apoptosis regulators as cancer therapy A Richardson, SB Kaye Current molecular pharmacology 1 (3), 244-254, 2008 | 62 | 2008 |
The synthesis and evaluation of thymoquinone analogues as anti-ovarian cancer and antimalarial agents OR Johnson-Ajinwo, I Ullah, H Mbye, A Richardson, P Horrocks, WW Li Bioorganic & Medicinal Chemistry Letters 28 (7), 1219-1222, 2018 | 60 | 2018 |
Preclinical evaluation of statins as a treatment for ovarian cancer E Robinson, M Nandi, LL Wilkinson, DM Arrowsmith, ADM Curtis, ... Gynecologic oncology 129 (2), 417-424, 2013 | 59 | 2013 |
Dietary geranylgeraniol can limit the activity of pitavastatin as a potential treatment for drug-resistant ovarian cancer E de Wolf, MI Abdullah, SM Jones, K Menezes, DM Moss, FP Drijfhout, ... Scientific reports 7 (1), 5410, 2017 | 56 | 2017 |
The poor design of clinical trials of statins in oncology may explain their failure–lessons for drug repurposing MI Abdullah, E de Wolf, MJ Jawad, A Richardson Cancer treatment reviews 69, 84-89, 2018 | 50 | 2018 |
The pituitary tumour epigenome: aberrations and prospects for targeted therapy K Yacqub-Usman, A Richardson, CV Duong, RN Clayton, WE Farrell Nature Reviews Endocrinology 8 (8), 486-494, 2012 | 50 | 2012 |
Use of a three-dimensional virtual environment to teach drug-receptor interactions A Richardson, L Bracegirdle, SIH McLachlan, SR Chapman American journal of pharmaceutical education 77 (1), 11, 2013 | 46 | 2013 |
The BH3 mimetic obatoclax accumulates in lysosomes and causes their alkalinization VA Stamelos, N Fisher, H Bamrah, C Voisey, JC Price, WE Farrell, ... PloS one 11 (3), e0150696, 2016 | 43 | 2016 |