Intrinsically disordered protein AK Dunker, JD Lawson, CJ Brown, RM Williams, P Romero, JS Oh, ... Journal of molecular graphics and modelling 19 (1), 26-59, 2001 | 2849 | 2001 |
Intrinsic disorder and protein function AK Dunker, CJ Brown, JD Lawson, LM Iakoucheva, Z Obradović Biochemistry 41 (21), 6573-6582, 2002 | 2115 | 2002 |
Intrinsic disorder in cell-signaling and cancer-associated proteins LM Iakoucheva, CJ Brown, JD Lawson, Z Obradović, AK Dunker Journal of molecular biology 323 (3), 573-584, 2002 | 1423 | 2002 |
Protein flexibility and intrinsic disorder P Radivojac, Z Obradovic, DK Smith, G Zhu, S Vucetic, CJ Brown, ... Protein Science 13 (1), 71-80, 2004 | 397 | 2004 |
DisProt: a database of protein disorder S Vucetic, Z Obradovic, V Vacic, P Radivojac, K Peng, LM Iakoucheva, ... Bioinformatics 21 (1), 137-140, 2005 | 286 | 2005 |
Is myosin a" back door" enzyme? RG Yount, D Lawson, I Rayment Biophysical journal 68 (4 Suppl), 44S, 1995 | 194 | 1995 |
Fragment-based discovery of a small molecule inhibitor of Bruton’s tyrosine kinase CR Smith, DR Dougan, M Komandla, T Kanouni, B Knight, JD Lawson, ... Journal of Medicinal Chemistry 58 (14), 5437-5444, 2015 | 74 | 2015 |
Molecular dynamics analysis of structural factors influencing back door pi release in myosin JD Lawson, E Pate, I Rayment, RG Yount Biophysical journal 86 (6), 3794-3803, 2004 | 66 | 2004 |
Structural model of the regulatory domain of smooth muscle heavy meromyosin JL Wahlstrom, MA Randall, JD Lawson, DE Lyons, WF Siems, GJ Crouch, ... Journal of Biological Chemistry 278 (7), 5123-5131, 2003 | 41 | 2003 |
A back-to-front fragment-based drug design search strategy targeting the DFG-out pocket of protein tyrosine kinases H Iwata, H Oki, K Okada, T Takagi, M Tawada, Y Miyazaki, S Imamura, ... ACS medicinal chemistry letters 3 (4), 342-346, 2012 | 31 | 2012 |
Fragment-based drug discovery of potent and selective MKK3/6 inhibitors M Adams, T Kobayashi, JD Lawson, M Saitoh, K Shimokawa, SV Bigi, ... Bioorganic & medicinal chemistry letters 26 (3), 1086-1089, 2016 | 25 | 2016 |
Discovery of potent, reversible MetAP2 inhibitors via fragment based drug discovery and structure based drug design—Part 2 C McBride, Z Cheruvallath, M Komandla, M Tang, P Farrell, JD Lawson, ... Bioorganic & Medicinal Chemistry Letters 26 (12), 2779-2783, 2016 | 23 | 2016 |
Discovery of potent, reversible MetAP2 inhibitors via fragment based drug discovery and structure based drug design—Part 1 Z Cheruvallath, M Tang, C McBride, M Komandla, J Miura, T Ton-Nu, ... Bioorganic & Medicinal Chemistry Letters 26 (12), 2774-2778, 2016 | 21 | 2016 |
Isolation of chloroform-resistant mutants of filamentous phage: localization in models of phage structure JS Oh, DR Davies, JD Lawson, GE Arnold, AK Dunker Journal of molecular biology 287 (3), 449-457, 1999 | 20 | 1999 |
Design, synthesis and optimization of 7-substituted-pyrazolo [4, 3-b] pyridine ALK5 (activin receptor-like kinase 5) inhibitors M Sabat, H Wang, N Scorah, JD Lawson, J Atienza, R Kamran, MS Hixon, ... Bioorganic & Medicinal Chemistry Letters 27 (9), 1955-1961, 2017 | 17 | 2017 |
Discovery of Potent, Selective, and Brain-Penetrant 1H-Pyrazol-5-yl-1H-pyrrolo[2,3-b]pyridines as Anaplastic Lymphoma Kinase (ALK) Inhibitors M Fushimi, I Fujimori, T Wakabayashi, T Hasui, Y Kawakita, K Imamura, ... Journal of Medicinal Chemistry 62 (10), 4915-4935, 2019 | 16 | 2019 |
Identification of AHCY inhibitors using novel high-throughput mass spectrometry N Uchiyama, DR Dougan, JD Lawson, H Kimura, S Matsumoto, Y Tanaka, ... Biochemical and Biophysical Research Communications 491 (1), 1-7, 2017 | 15 | 2017 |
MET tyrosine kinase inhibition enhances the antitumor efficacy of an HGF antibody PJ Farrell, J Matuszkiewicz, D Balakrishna, S Pandya, MS Hixon, ... Molecular cancer therapeutics 16 (7), 1269-1278, 2017 | 13 | 2017 |
Structure-based optimization of 1H-imidazole-2-carboxamides as Axl kinase inhibitors utilizing a Mer mutant surrogate W Keung, A Boloor, J Brown, A Kiryanov, A Gangloff, JD Lawson, ... Bioorganic & Medicinal Chemistry Letters 27 (4), 1099-1104, 2017 | 11 | 2017 |
Design, synthesis and optimization of novel Alk5 (activin-like kinase 5) inhibitors H Wang, JD Lawson, N Scorah, R Kamran, MS Hixon, J Atienza, ... Bioorganic & medicinal chemistry letters 26 (17), 4334-4339, 2016 | 9 | 2016 |