Specific structural determinants are responsible for the antioxidant activity and the cell cycle effects of resveratrol LA Stivala, M Savio, F Carafoli, P Perucca, L Bianchi, G Maga, L Forti, ... Journal of Biological Chemistry 276 (25), 22586-22594, 2001 | 625 | 2001 |
Multiple roles of the cell cycle inhibitor p21CDKN1A in the DNA damage response O Cazzalini, AI Scovassi, M Savio, LA Stivala, E Prosperi Mutation Research/Reviews in Mutation Research 704 (1-3), 12-20, 2010 | 511 | 2010 |
Anthocyanins protect against DNA damage induced by tert-butyl-hydroperoxide in rat smooth muscle and hepatoma cells MC Lazze, R Pizzala, M Savio, LA Stivala, E Prosperi, L Bianchi Mutation Research/Genetic Toxicology and Environmental Mutagenesis 535 (1 …, 2003 | 313 | 2003 |
Arylthioindole inhibitors of tubulin polymerization. 3. Biological evaluation, structure− activity relationships and molecular modeling studies G La Regina, MC Edler, A Brancale, S Kandil, A Coluccia, F Piscitelli, ... Journal of medicinal chemistry 50 (12), 2865-2874, 2007 | 214 | 2007 |
Biology of the cell cycle inhibitor p21CDKN1A: molecular mechanisms and relevance in chemical toxicology I Dutto, M Tillhon, O Cazzalini, LA Stivala, E Prosperi Archives of toxicology 89, 155-178, 2015 | 208 | 2015 |
The cyclin-dependent kinase inhibitors olomoucine and roscovitine arrest human fibroblasts in G1 phase by specific inhibition of CDK2 kinase activity F Alessi, S Quarta, M Savio, F Riva, L Rossi, LA Stivala, AI Scovassi, ... Experimental cell research 245 (1), 8-18, 1998 | 179 | 1998 |
Multiple roles of the proliferating cell nuclear antigen: DNA replication, repair and cell cycle control E Prosperi Progress in cell cycle research, 193-210, 1997 | 174 | 1997 |
Human Proliferating Cell Nuclear Antigen, Poly (ADP-ribose) Polymerase-1, and p21 waf1/cip1: A DYNAMIC EXCHANGE OF PARTNERS I Frouin, G Maga, M Denegri, F Riva, M Savio, S Spadari, E Prosperi, ... Journal of Biological Chemistry 278 (41), 39265-39268, 2003 | 131 | 2003 |
Targeting proliferating cell nuclear antigen (PCNA) as an effective strategy to inhibit tumor cell proliferation M Cardano, C Tribioli, E Prosperi Current cancer drug targets 20 (4), 240-252, 2020 | 118 | 2020 |
Replication fork stalling in WRN-deficient cells is overcome by prompt activation of a MUS81-dependent pathway A Franchitto, LM Pirzio, E Prosperi, O Sapora, M Bignami, P Pichierri The Journal of cell biology 183 (2), 241-252, 2008 | 113 | 2008 |
CBP and p300 acetylate PCNA to link its degradation with nucleotide excision repair synthesis O Cazzalini, S Sommatis, M Tillhon, I Dutto, A Bachi, A Rapp, T Nardo, ... Nucleic acids research 42 (13), 8433-8448, 2014 | 107 | 2014 |
Free radical-dependent DNA lesions are involved in the delayed cardiotoxicity induced by adriamycin in the rat. E Monti, E Prosperi, R Supino, G Bottiroli Anticancer research 15 (1), 193-197, 1995 | 99 | 1995 |
CREBBP and p300 lysine acetyl transferases in the DNA damage response I Dutto, C Scalera, E Prosperi Cellular and Molecular Life Sciences 75, 1325-1338, 2018 | 95 | 2018 |
Proliferating cell nuclear antigen bound to DNA synthesis sites: phosphorylation and association with cyclin D1 and cyclin A E Prosperi, AI Scovassi, LA Stivala, L Bianchi Experimental cell research 215 (2), 257-262, 1994 | 95 | 1994 |
p21CDKN1A does not interfere with loading of PCNA at DNA replication sites, but inhibits subsequent binding of DNA polymerase d at the G1/S phase transition O Cazzalini, P Perucca, F Riva, LA Stivala, L Bianchi, V Vannini, ... Cell Cycle 2 (6), 595-602, 2003 | 85 | 2003 |
Interaction of p21 CDKN1A with PCNA regulates the histone acetyltransferase activity of p300 in nucleotide excision repair O Cazzalini, P Perucca, M Savio, D Necchi, L Bianchi, LA Stivala, ... Nucleic acids research 36 (5), 1713-1722, 2008 | 78 | 2008 |
Multiple effects of berberine derivatives on colon cancer cells LM Guaman Ortiz, M Tillhon, M Parks, I Dutto, E Prosperi, M Savio, ... BioMed research international 2014, 2014 | 76 | 2014 |
Spatiotemporal dynamics of p21CDKN1A protein recruitment to DNA-damage sites and interaction with proliferating cell nuclear antigen P Perucca, O Cazzalini, O Mortusewicz, D Necchi, M Savio, T Nardo, ... Journal of cell science 119 (8), 1517-1527, 2006 | 72 | 2006 |
p21waf1/cip1-null human fibroblasts are deficient in nucleotide excision repair downstream the recruitment of PCNA to DNA repair sites LA Stivala, F Riva, O Cazzalini, M Savio, E Prosperi Oncogene 20 (5), 563-570, 2001 | 72 | 2001 |
Loss of p21CDKN1A impairs entry to quiescence and activates a DNA damage response in normal fibroblasts induced to quiescence P Perucca, O Cazzalini, M Madine, M Savio, RA Laskey, V Vannini, ... Cell cycle 8 (1), 105-114, 2009 | 71 | 2009 |