Simon Arthur
Simon Arthur
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The selectivity of protein kinase inhibitors: a further update
J Bain, L Plater, M Elliott, N Shpiro, C Hastie, H Mclauchlan, I Klevernic, ...
Biochem. J 408, 297-315, 2007
Mitogen-activated protein kinases in innate immunity
JSC Arthur, SC Ley
Nature Reviews Immunology 13 (9), 679-692, 2013
MSK2 and MSK1 mediate the mitogen-and stress-induced phosphorylation of histone H3 and HMG-14
A Soloaga, S Thomson, GR Wiggin, N Rampersaud, MH Dyson, ...
The EMBO journal 22 (11), 2788-2797, 2003
The role of 3-phosphoinositide-dependent protein kinase 1 in activating AGC kinases defined in embryonic stem cells
MR Williams, JSC Arthur, A Balendran, J van der Kaay, V Poli, P Cohen, ...
Current Biology 10 (8), 439-448, 2000
MSK1 and MSK2 are required for the mitogen-and stress-induced phosphorylation of CREB and ATF1 in fibroblasts
GR Wiggin, A Soloaga, JM Foster, V Murray-Tait, P Cohen, JSC Arthur
Molecular and cellular biology 22 (8), 2871-2881, 2002
Disruption of the murine calpain small subunit gene, Capn4: calpain is essential for embryonic development but not for cell growth and division
JSC Arthur, JS Elce, C Hegadorn, K Williams, PA Greer
Molecular and cellular biology 20 (12), 4474-4481, 2000
Activation of the canonical IKK complex by K63/M1-linked hybrid ubiquitin chains
CH Emmerich, A Ordureau, S Strickson, JSC Arthur, PGA Pedrioli, ...
Proceedings of the National Academy of Sciences 110 (38), 15247-15252, 2013
The p38 MAPK pathway is essential for skeletogenesis and bone homeostasis in mice
MB Greenblatt, JH Shim, W Zou, D Sitara, M Schweitzer, D Hu, S Lotinun, ...
The Journal of clinical investigation 120 (7), 2457, 2010
The kinases MSK1 and MSK2 act as negative regulators of Toll-like receptor signaling
O Ananieva, J Darragh, C Johansen, JM Carr, J McIlrath, JM Park, ...
Nature immunology 9 (9), 1028-1036, 2008
Signaling pathways and genes that inhibit pathogen-induced macrophage apoptosis—CREB and NF-κB as key regulators
JM Park, FR Greten, A Wong, RJ Westrick, JSC Arthur, K Otsu, ...
Immunity 23 (3), 319-329, 2005
The kinase p38α serves cell type–specific inflammatory functions in skin injury and coordinates pro-and anti-inflammatory gene expression
C Kim, Y Sano, K Todorova, BA Carlson, L Arpa, A Celada, T Lawrence, ...
Nature immunology 9 (9), 1019-1027, 2008
Posttranslational regulation of tristetraprolin subcellular localization and protein stability by p38 mitogen-activated protein kinase and extracellular signal-regulated kinase …
M Brook, CR Tchen, T Santalucia, J McIlrath, JSC Arthur, J Saklatvala, ...
Molecular and cellular biology 26 (6), 2408-2418, 2006
Parsing molecular and behavioral effects of cocaine in mitogen-and stress-activated protein kinase-1-deficient mice
K Brami-Cherrier, E Valjent, D Hervé, J Darragh, JC Corvol, C Pages, ...
The Journal of neuroscience 25 (49), 11444-11454, 2005
Reduced cell migration and disruption of the actin cytoskeleton in calpain-deficient embryonic fibroblasts
N Dourdin, AK Bhatt, P Dutt, PA Greer, JSC Arthur, JS Elce, ...
Journal of Biological Chemistry 276 (51), 48382-48388, 2001
Generation and characterization of p38β (MAPK11) gene-targeted mice
VA Beardmore, HJ Hinton, C Eftychi, M Apostolaki, M Armaka, J Darragh, ...
Molecular and cellular biology 25 (23), 10454-10464, 2005
Phosphorylation of the protein kinase mutated in Peutz-Jeghers cancer syndrome, LKB1/STK11, at Ser431 by p90RSK and cAMP-dependent protein kinase, but not its farnesylation at …
GP Sapkota, A Kieloch, JM Lizcano, S Lain, JSC Arthur, MR Williams, ...
Journal of Biological Chemistry 276 (22), 19469-19482, 2001
The nuclear kinase mitogen-and stress-activated protein kinase 1 regulates hippocampal chromatin remodeling in memory formation
WB Chwang, JS Arthur, A Schumacher, JD Sweatt
The Journal of Neuroscience 27 (46), 12732-12742, 2007
p38γ regulates the localisation of SAP97 in the cytoskeleton by modulating its interaction with GKAP
G Sabio, JSC Arthur, Y Kuma, M Peggie, J Carr, V Murray-Tait, F Centeno, ...
The EMBO journal 24 (6), 1134-1145, 2005
Structure of a calpain Ca2+-binding domain reveals a novel EF-hand and Ca2+-induced conformational changes
H Blanchard, P Grochulski, Y Li, JSC Arthur, PL Davies, JS Elce, M Cygler
Nature Structural & Molecular Biology 4 (7), 532-538, 1997
Phosphorylation of CRTC3 by the salt-inducible kinases controls the interconversion of classically activated and regulatory macrophages
K Clark, KF MacKenzie, K Petkevicius, Y Kristariyanto, J Zhang, HG Choi, ...
Proceedings of the National Academy of Sciences 109 (42), 16986-16991, 2012
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