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Sevin Turcan
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IDH mutation impairs histone demethylation and results in a block to cell differentiation
C Lu, PS Ward, GS Kapoor, D Rohle, S Turcan, O Abdel-Wahab, ...
Nature 483 (7390), 474-478, 2012
21322012
IDH1 mutation is sufficient to establish the glioma hypermethylator phenotype
S Turcan, D Rohle, A Goenka, LA Walsh, F Fang, E Yilmaz, C Campos, ...
Nature 483 (7390), 479-483, 2012
21062012
An inhibitor of mutant IDH1 delays growth and promotes differentiation of glioma cells
D Rohle, J Popovici-Muller, N Palaskas, S Turcan, C Grommes, ...
Science 340 (6132), 626-630, 2013
12622013
Glutamatergic synaptic input to glioma cells drives brain tumour progression
V Venkataramani, DI Tanev, C Strahle, A Studier-Fischer, L Fankhauser, ...
Nature 573 (7775), 532-538, 2019
7162019
The mutational landscape of adenoid cystic carcinoma
AS Ho, K Kannan, DM Roy, LGT Morris, I Ganly, N Katabi, D Ramaswami, ...
Nature genetics 45 (7), 791-798, 2013
4702013
BCAT1 promotes cell proliferation through amino acid catabolism in gliomas carrying wild-type IDH1
M Tönjes, S Barbus, YJ Park, W Wang, M Schlotter, AM Lindroth, ...
Nature medicine 19 (7), 901-908, 2013
4652013
Recurrent somatic mutation of FAT1 in multiple human cancers leads to aberrant Wnt activation
LGT Morris, AM Kaufman, Y Gong, D Ramaswami, LA Walsh, Ş Turcan, ...
Nature genetics 45 (3), 253-261, 2013
4322013
Suppression of antitumor T cell immunity by the oncometabolite (R)-2-hydroxyglutarate
L Bunse, S Pusch, T Bunse, F Sahm, K Sanghvi, M Friedrich, D Alansary, ...
Nature medicine 24 (8), 1192-1203, 2018
4172018
Breast cancer methylomes establish an epigenomic foundation for metastasis
F Fang, S Turcan, A Rimner, A Kaufman, D Giri, LGT Morris, R Shen, ...
Science translational medicine 3 (75), 75ra25-75ra25, 2011
3462011
Integrated genomic characterization of IDH1-mutant glioma malignant progression
H Bai, AS Harmancı, EZ Erson-Omay, J Li, S Coşkun, M Simon, ...
Nature genetics 48 (1), 59-66, 2016
3052016
Efficient induction of differentiation and growth inhibition in IDH1 mutant glioma cells by the DNMT Inhibitor Decitabine
S Turcan, AWM Fabius, A Borodovsky, A Pedraza, C Brennan, J Huse, ...
Oncotarget 4 (10), 1729, 2013
2762013
5-azacytidine reduces methylation, promotes differentiation and induces tumor regression in a patient-derived IDH1 mutant glioma xenograft
A Borodovsky, V Salmasi, S Turcan, AWM Fabius, GS Baia, CG Eberhart, ...
Oncotarget 4 (10), 1737, 2013
1932013
Pan-cancer genetic analysis identifies PARK2 as a master regulator of G1/S cyclins
Y Gong, TI Zack, LGT Morris, K Lin, E Hukkelhoven, R Raheja, IL Tan, ...
Nature genetics 46 (6), 588-594, 2014
1692014
Mutant-IDH1-dependent chromatin state reprogramming, reversibility, and persistence
S Turcan, V Makarov, J Taranda, Y Wang, AWM Fabius, W Wu, Y Zheng, ...
Nature genetics 50 (1), 62-72, 2018
1662018
The α10 nicotinic acetylcholine receptor subunit is required for normal synaptic function and integrity of the olivocochlear system
DE Vetter, E Katz, SF Maison, J Taranda, S Turcan, J Ballestero, ...
Proceedings of the National Academy of Sciences 104 (51), 20594-20599, 2007
1452007
An integrated systems biology approach identifies TRIM25 as a key determinant of breast cancer metastasis
LA Walsh, MJ Alvarez, EY Sabio, M Reyngold, V Makarov, S Mukherjee, ...
Cell reports 20 (7), 1623-1640, 2017
992017
Transcriptional diversity of long-term glioblastoma survivors
NK Gerber, A Goenka, S Turcan, M Reyngold, V Makarov, K Kannan, ...
Neuro-oncology 16 (9), 1186-1195, 2014
972014
Targeting therapeutic vulnerabilities with PARP inhibition and radiation in IDH-mutant gliomas and cholangiocarcinomas
Y Wang, AT Wild, S Turcan, WH Wu, C Sigel, DS Klimstra, X Ma, Y Gong, ...
Science Advances 6 (17), eaaz3221, 2020
852020
Origin of gliomas
D Cahill, S Turcan
Seminars in neurology 38 (01), 005-010, 2018
742018
Epigenetic therapy: use of agents targeting deacetylation and methylation in cancer management
AS Ho, S Turcan, TA Chan
OncoTargets and therapy, 223-232, 2013
612013
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