Andrew N. Blackford

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Stephen JacksonUniversity of CambridgeVerified email at gurdon.cam.ac.uk
Roger GrandReader In Experimental Cancer SciencesVerified email at bham.ac.uk
Benedikt KesslerProfessor of Biochemistry and Life Science Mass Spectrometry, University of Oxford, UKVerified email at ndm.ox.ac.uk
Tom L BlundellEmeritus Professor of Biochemistry, University of CambridgeVerified email at cam.ac.uk
Takashi OchiUniversity of LeedsVerified email at leeds.ac.uk
Carol V RobinsonProfessor of Chemistry University of OxfordVerified email at chem.ox.ac.uk
Gabriel BalmusUniversity of CambridgeVerified email at cam.ac.uk
Andrew J DeansLab head, St Vincent's InstituteVerified email at svi.edu.au
Simon BoultonPrincipal Group Leader, The Francis Crick InstituteVerified email at crick.ac.uk
Laurence PearlProfessor of Structural Biology, University of SussexVerified email at sussex.ac.uk
Jos JonkersSenior Group Leader, Division of Molecular Pathology, Netherlands Cancer Institute, Oncode InstituteVerified email at nki.nl
Stephen WestFrancis Crick InstituteVerified email at crick.ac.uk
Michael L. NielsenNovo Nordisk Foundation Center for Protein ResearchVerified email at cpr.ku.dk
Daniel DurocherThe Lunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital and Department of MolecularVerified email at lunenfeld.ca
Matthias AltmeyerUniversity of ZurichVerified email at uzh.ch
Fena OchsAssociate Professor BRIC CopenhagenVerified email at bric.ku.dk
Alessandro CostaPrincipal Group leader, The Francis Crick Institute, LondonVerified email at crick.ac.uk
Ross ChapmanMedical Research Council Molecular Haematology Unit, University of OxfordVerified email at imm.ox.ac.uk
Matthew HurlesDirector, Senior Group Leader in Human Genetics, Wellcome Sanger InstituteVerified email at sanger.ac.uk
Andrew P. JacksonUniversity of EdinburghVerified email at igmm.ed.ac.uk

Andrew N. Blackford

Associate Professor, University of Oxford

Verified email at imm.ox.ac.uk - Homepage

DNA Repair Mitosis Cancer Protein Evolution Protein Phosphorylation


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ATM, ATR, and DNA-PK: The Trinity at the Heart of the DNA Damage Response AN Blackford, SP Jackson Molecular cell 66 (6), 801-817, 2017	1684	2017
PAXX, a paralog of XRCC4 and XLF, interacts with Ku to promote DNA double-strand break repair T Ochi, AN Blackford, J Coates, S Jhujh, S Mehmood, N Tamura, ... Science 347 (6218), 185-188, 2015	366	2015
Regulation of DNA-end resection by hnRNPU-like proteins promotes DNA double-strand break signaling and repair SE Polo, AN Blackford, JR Chapman, L Baskcomb, S Gravel, A Rusch, ... Molecular cell 45 (4), 505-516, 2012	202	2012
Targeting DNA damage response pathways in cancer FJ Groelly, M Fawkes, RA Dagg, AN Blackford, M Tarsounas Nature Reviews Cancer 23 (2), 78-94, 2023	196	2023
BOD1L is required to suppress deleterious resection of stressed replication forks MR Higgs, JJ Reynolds, A Winczura, AN Blackford, V Borel, ES Miller, ... Molecular cell 59 (3), 462-477, 2015	188	2015
ATR activation and replication fork restart are defective in FANCM‐deficient cells RA Schwab, AN Blackford, W Niedzwiedz The EMBO journal 29 (4), 806-818, 2010	171	2010
Adenovirus E1B 55-kilodalton protein: multiple roles in viral infection and cell transformation AN Blackford, RJA Grand Journal of virology 83 (9), 4000-4012, 2009	139	2009
Adenovirus 12 E4orf6 inhibits ATR activation by promoting TOPBP1 degradation AN Blackford, RN Patel, NA Forrester, K Theil, P Groitl, GS Stewart, ... Proceedings of the National Academy of Sciences 107 (27), 12251-12256, 2010	101	2010
MDC1 interacts with TOPBP1 to maintain chromosomal stability during mitosis PA Leimbacher, SE Jones, AMK Shorrocks, M de Marco Zompit, M Day, ... Molecular cell 74 (3), 571-583. e8, 2019	100	2019
The ASCIZ-DYNLL1 axis promotes 53BP1-dependent non-homologous end joining and PARP inhibitor sensitivity JR Becker, R Cuella-Martin, M Barazas, R Liu, C Oliveira, AW Oliver, ... Nature communications 9 (1), 5406, 2018	91	2018
PGBD5 promotes site-specific oncogenic mutations in human tumors AG Henssen, R Koche, J Zhuang, E Jiang, C Reed, A Eisenberg, E Still, ... Nature genetics 49 (7), 1005-1014, 2017	87	2017
TRAIP promotes DNA damage response during genome replication and is mutated in primordial dwarfism ME Harley, O Murina, A Leitch, MR Higgs, LS Bicknell, G Yigit, ... Nature genetics 48 (1), 36-43, 2016	87	2016
Serotype-specific inactivation of the cellular DNA damage response during adenovirus infection NA Forrester, GG Sedgwick, A Thomas, AN Blackford, T Speiseder, ... Journal of virology 85 (5), 2201-2211, 2011	87	2011
Synthetic lethality between PAXX and XLF in mammalian development G Balmus, AC Barros, PWG Wijnhoven, C Lescale, HL Hasse, K Boroviak, ... Genes & development 30 (19), 2152-2157, 2016	83	2016
The DNA translocase activity of FANCM protects stalled replication forks AN Blackford, RA Schwab, J Nieminuszczy, AJ Deans, SC West, ... Human molecular genetics 21 (9), 2005-2016, 2012	83	2012
TOPBP1 recruits TOP2A to ultra-fine anaphase bridges to aid in their resolution R Broderick, J Nieminuszczy, AN Blackford, A Winczura, W Niedzwiedz Nature communications 6 (1), 6572, 2015	81	2015
Specific roles of XRCC4 paralogs PAXX and XLF during V (D) J recombination C Lescale, HL Hasse, AN Blackford, G Balmus, JJ Bianchi, W Yu, ... Cell reports 16 (11), 2967-2979, 2016	78	2016
USP4 auto-deubiquitylation promotes homologous recombination P Wijnhoven, R Konietzny, AN Blackford, J Travers, BM Kessler, R Nishi, ... Molecular cell 60 (3), 362-373, 2015	78	2015
A role for E1B-AP5 in ATR signaling pathways during adenovirus infection AN Blackford, RK Bruton, O Dirlik, GS Stewart, AMR Taylor, T Dobner, ... Journal of virology 82 (15), 7640-7652, 2008	73	2008
TopBP1 interacts with BLM to maintain genome stability but is dispensable for preventing BLM degradation AN Blackford, J Nieminuszczy, RA Schwab, Y Galanty, SP Jackson, ... Molecular cell 57 (6), 1133-1141, 2015	72	2015

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