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Kapil Tahlan
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Minimum information about a biosynthetic gene cluster
MH Medema, R Kottmann, P Yilmaz, M Cummings, JB Biggins, K Blin, ...
Nature chemical biology 11 (9), 625-631, 2015
8422015
SQ109 targets MmpL3, a membrane transporter of trehalose monomycolate involved in mycolic acid donation to the cell wall core of Mycobacterium tuberculosis
K Tahlan, R Wilson, DB Kastrinsky, K Arora, V Nair, E Fischer, SW Barnes, ...
Antimicrobial agents and chemotherapy 56 (4), 1797-1809, 2012
5662012
Uptake of unnatural trehalose analogs as a reporter for Mycobacterium tuberculosis
KM Backus, HI Boshoff, CS Barry, O Boutureira, MK Patel, F D'hooge, ...
Nature chemical biology 7 (4), 228-235, 2011
2422011
Biosynthesis and recycling of nicotinamide cofactors in Mycobacterium tuberculosis: an essential role for NAD in nonreplicating bacilli
HIM Boshoff, X Xu, K Tahlan, CS Dowd, K Pethe, LR Camacho, TH Park, ...
Journal of Biological Chemistry 283 (28), 19329-19341, 2008
1932008
Initiation of actinorhodin export in Streptomyces coelicolor
K Tahlan, SK Ahn, A Sing, TD Bodnaruk, AR Willems, AR Davidson, ...
Molecular microbiology 63 (4), 951-961, 2007
1602007
A community resource for paired genomic and metabolomic data mining
MA Schorn, S Verhoeven, L Ridder, F Huber, DD Acharya, AA Aksenov, ...
Nature Chemical Biology 17 (4), 363-368, 2021
1012021
Expression of ccaR, Encoding the Positive Activator of Cephamycin C and Clavulanic Acid Production in Streptomyces clavuligerus, Is Dependent on bldG
DRD Bignell, K Tahlan, KR Colvin, SE Jensen, BK Leskiw
Antimicrobial agents and chemotherapy 49 (4), 1529-1541, 2005
862005
Origins of the β-lactam rings in natural products
K Tahlan, SE Jensen
The Journal of antibiotics 66 (7), 401-410, 2013
752013
Crystal structures of the Streptomyces coelicolor TetR-like protein ActR alone and in complex with actinorhodin or the actinorhodin biosynthetic precursor (S)-DNPA
AR Willems, K Tahlan, T Taguchi, K Zhang, ZZ Lee, K Ichinose, MS Junop, ...
Journal of molecular biology 376 (5), 1377-1387, 2008
722008
Klebsiella species associated with bovine mastitis in Newfoundland
MP Podder, L Rogers, PK Daley, GP Keefe, HG Whitney, K Tahlan
PloS one 9 (9), e106518, 2014
712014
Two sets of paralogous genes encode the enzymes involved in the early stages of clavulanic acid and clavam metabolite biosynthesis in Streptomyces clavuligerus
K Tahlan, HU Park, A Wong, PH Beatty, SE Jensen
Antimicrobial agents and chemotherapy 48 (3), 930-939, 2004
692004
A two-step mechanism for the activation of actinorhodin export and resistance in Streptomyces coelicolor
Y Xu, A Willems, C Au-Yeung, K Tahlan, JR Nodwell
MBio 3 (5), 10.1128/mbio. 00191-12, 2012
602012
Ligand recognition by ActR, a TetR-like regulator of actinorhodin export
K Tahlan, Z Yu, Y Xu, AR Davidson, JR Nodwell
Journal of molecular biology 383 (4), 753-761, 2008
552008
5S clavam biosynthetic genes are located in both the clavam and paralog gene clusters in Streptomyces clavuligerus
K Tahlan, C Anders, A Wong, RH Mosher, PH Beatty, MJ Brumlik, A Griffin, ...
Chemistry & biology 14 (2), 131-142, 2007
492007
The Paralogous Pairs of Genes Involved in Clavulanic Acid and Clavam Metabolite Biosynthesis Are Differently Regulated in Streptomyces clavuligerus
K Tahlan, C Anders, SE Jensen
Journal of bacteriology 186 (18), 6286-6297, 2004
472004
Three unlinked gene clusters are involved in clavam metabolite biosynthesis in Streptomyces clavuligerus
K Tahlan, HU Park, SE Jensen
Canadian journal of microbiology 50 (10), 803-810, 2004
442004
Genome-Wide Diversity and Phylogeography of Mycobacterium avium subsp. paratuberculosis in Canadian Dairy Cattle
C Ahlstrom, HW Barkema, K Stevenson, RN Zadoks, R Biek, R Kao, ...
Plos one 11 (2), e0149017, 2016
322016
Investigation of Transcription Repression and Small-Molecule Responsiveness by TetR-Like Transcription Factors Using a Heterologous Escherichia coli-Based …
SK Ahn, K Tahlan, Z Yu, J Nodwell
Journal of bacteriology 189 (18), 6655-6664, 2007
292007
Comparative Genomics and Metabolomics Analyses of Clavulanic Acid-Producing Streptomyces Species Provides Insight Into Specialized Metabolism
NF AbuSara, BM Piercey, MA Moore, AA Shaikh, LF Nothias, ...
Frontiers in Microbiology 10, 2550, 2019
282019
Transcriptional and translational analysis of the ccaR gene from Streptomyces clavuligerus
L Wang, K Tahlan, TL Kaziuk, DC Alexander, SE Jensen
Microbiology 150 (12), 4137-4145, 2004
272004
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