Ayyalusamy Ramamoorthy
Ayyalusamy Ramamoorthy
Robert W. Parry Collegiate Professor of Chemistry and Biophysics, University of Michigan
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Ultrastrong and stiff layered polymer nanocomposites
P Podsiadlo, AK Kaushik, EM Arruda, AM Waas, BS Shim, J Xu, ...
Science 318 (5847), 80-83, 2007
Studies on anticancer activities of antimicrobial peptides
DW Hoskin, A Ramamoorthy
Biochimica et Biophysica Acta (BBA)-Biomembranes 1778 (2), 357-375, 2008
LL-37, the only human member of the cathelicidin family of antimicrobial peptides
UHN Dürr, US Sudheendra, A Ramamoorthy
Biochimica et Biophysica Acta (BBA)-Biomembranes 1758 (9), 1408-1425, 2006
Mechanism of lipid bilayer disruption by the human antimicrobial peptide, LL-37
KA Henzler Wildman, DK Lee, A Ramamoorthy
Biochemistry 42 (21), 6545-6558, 2003
High-resolution heteronuclear dipolar solid-state NMR spectroscopy
CH Wu, A Ramamoorthy, SJ Opella
Journal of Magnetic Resonance Series A 109, 270-270, 1994
A partially folded structure of amyloid-beta (1–40) in an aqueous environment
S Vivekanandan, JR Brender, SY Lee, A Ramamoorthy
Biochemical and biophysical research communications 411 (2), 312-316, 2011
MSI-78, an analogue of the magainin antimicrobial peptides, disrupts lipid bilayer structure via positive curvature strain
KJ Hallock, DK Lee, A Ramamoorthy
Biophysical journal 84 (5), 3052-3060, 2003
The human beta-defensin-3, an antibacterial peptide with multiple biological functions
V Dhople, A Krukemeyer, A Ramamoorthy
Biochimica et Biophysica Acta (BBA)-Biomembranes 1758 (9), 1499-1512, 2006
Misfolded proteins in Alzheimer's disease and type II diabetes
AS DeToma, S Salamekh, A Ramamoorthy, MH Lim
Chemical Society Reviews 41 (2), 608-621, 2012
Membrane disruption and early events in the aggregation of the diabetes related peptide IAPP from a molecular perspective
JR Brender, S Salamekh, A Ramamoorthy
Accounts of chemical research 45 (3), 454-462, 2012
Differences between amyloid-β aggregation in solution and on the membrane: insights into elucidation of the mechanistic details of Alzheimer's disease
SA Kotler, P Walsh, JR Brender, A Ramamoorthy
Chemical Society Reviews 43 (19), 6692-6700, 2014
Two-step mechanism of membrane disruption by Aβ through membrane fragmentation and pore formation
MFM Sciacca, SA Kotler, JR Brender, J Chen, D Lee, A Ramamoorthy
Biophysical journal 103 (4), 702-710, 2012
The magic of bicelles lights up membrane protein structure
UHN Dürr, M Gildenberg, A Ramamoorthy
Chemical reviews 112 (11), 6054-6074, 2012
Structure, membrane orientation, mechanism, and function of pexiganan—a highly potent antimicrobial peptide designed from magainin
LM Gottler, A Ramamoorthy
Biochimica et Biophysica Acta (BBA)-Biomembranes 1788 (8), 1680-1686, 2009
Perturbation of the hydrophobic core of lipid bilayers by the human antimicrobial peptide LL-37
KA Henzler-Wildman, GV Martinez, MF Brown, A Ramamoorthy
Biochemistry 43 (26), 8459-8469, 2004
Design of small molecules that target metal-Aβ species and regulate metal-induced Aβ aggregation and neurotoxicity
JS Choi, JJ Braymer, RPR Nanga, A Ramamoorthy, MH Lim
Proceedings of the National Academy of Sciences 107 (51), 21990-21995, 2010
Determining the effects of lipophilic drugs on membrane structure by solid-state NMR spectroscopy: the case of the antioxidant curcumin
J Barry, M Fritz, JR Brender, PES Smith, DK Lee, A Ramamoorthy
Journal of the American Chemical Society 131 (12), 4490-4498, 2009
Inhibition of amyloid peptide fibrillation by inorganic nanoparticles: functional similarities with proteins
SI Yoo, M Yang, JR Brender, V Subramanian, K Sun, NE Joo, SH Jeong, ...
Angewandte Chemie International Edition 50 (22), 5110-5115, 2011
Direct observation of lipid bilayer disruption by poly (amidoamine) dendrimers
A Mecke, S Uppuluri, TM Sassanella, DK Lee, A Ramamoorthy, ...
Chemistry and physics of lipids 132 (1), 3-14, 2004
Complete resolution of the solid-state NMR spectrum of a uniformly 15N-labeled membrane protein in phospholipid bilayers
FM Marassi, A Ramamoorthy, SJ Opella
Proceedings of the National Academy of Sciences 94 (16), 8551-8556, 1997
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