| A transgenic Alzheimer rat with plaques, tau pathology, behavioral impairment, oligomeric aβ, and frank neuronal loss RM Cohen, K Rezai-Zadeh, TM Weitz, A Rentsendorj, D Gate, I Spivak, ... Journal of Neuroscience 33 (15), 6245-6256, 2013 | 535 | 2013 |
| The adaptive immune system restrains Alzheimer’s disease pathogenesis by modulating microglial function SE Marsh, EM Abud, A Lakatos, A Karimzadeh, ST Yeung, H Davtyan, ... Proceedings of the National Academy of Sciences 113 (9), E1316-E1325, 2016 | 368 | 2016 |
| Development and validation of a simplified method to generate human microglia from pluripotent stem cells A McQuade, M Coburn, CH Tu, J Hasselmann, H Davtyan, ... Molecular neurodegeneration 13, 1-13, 2018 | 288 | 2018 |
| Development of a chimeric model to study and manipulate human microglia in vivo J Hasselmann, MA Coburn, W England, DXF Velez, SK Shabestari, ... Neuron 103 (6), 1016-1033. e10, 2019 | 252 | 2019 |
| Deletion of a Csf1r enhancer selectively impacts CSF1R expression and development of tissue macrophage populations R Rojo, A Raper, DD Ozdemir, L Lefevre, K Grabert, ... Nature communications 10 (1), 3215, 2019 | 229 | 2019 |
| Gene expression and functional deficits underlie TREM2-knockout microglia responses in human models of Alzheimer’s disease A McQuade, YJ Kang, J Hasselmann, A Jairaman, A Sotelo, M Coburn, ... Nature communications 11 (1), 5370, 2020 | 205 | 2020 |
| Immunogenicity, efficacy, safety, and mechanism of action of epitope vaccine (Lu AF20513) for Alzheimer's disease: prelude to a clinical trial H Davtyan, A Ghochikyan, I Petrushina, A Hovakimyan, A Davtyan, ... Journal of Neuroscience 33 (11), 4923-4934, 2013 | 183 | 2013 |
| The binding of ethidium bromide with DNA: interaction with single-and double-stranded structures PO Vardevanyan, AP Antonyan, MA Parsadanyan, HG Davtyan, ... Experimental & Molecular Medicine 35 (6), 527-533, 2003 | 167 | 2003 |
| Reducing AD-like pathology in 3xTg-AD mouse model by DNA epitope vaccine—a novel immunotherapeutic strategy N Movsesyan, A Ghochikyan, M Mkrtichyan, I Petrushina, H Davtyan, ... PloS one 3 (5), e2124, 2008 | 139 | 2008 |
| Alzheimer's disease peptide epitope vaccine reduces insoluble but not soluble/oligomeric Aβ species in amyloid precursor protein transgenic mice I Petrushina, A Ghochikyan, M Mktrichyan, G Mamikonyan, N Movsesyan, ... Journal of Neuroscience 27 (46), 12721-12731, 2007 | 128 | 2007 |
| Modeling sporadic Alzheimer's disease in human brain organoids under serum exposure X Chen, G Sun, E Tian, M Zhang, H Davtyan, TG Beach, EM Reiman, ... Advanced Science 8 (18), 2101462, 2021 | 92 | 2021 |
| C9orf72 deficiency promotes microglial-mediated synaptic loss in aging and amyloid accumulation D Lall, I Lorenzini, TA Mota, S Bell, TE Mahan, JD Ulrich, H Davtyan, ... Neuron 109 (14), 2275-2291. e8, 2021 | 89 | 2021 |
| Induction of mesoderm and neural crest-derived pericytes from human pluripotent stem cells to study blood-brain barrier interactions T Faal, DTT Phan, H Davtyan, VM Scarfone, E Varady, M Blurton-Jones, ... Stem Cell Reports 12 (3), 451-460, 2019 | 88 | 2019 |
| Plaque-associated human microglia accumulate lipid droplets in a chimeric model of Alzheimer’s disease C Claes, EP Danhash, J Hasselmann, JP Chadarevian, SK Shabestari, ... Molecular neurodegeneration 16, 1-11, 2021 | 76 | 2021 |
| DNA prime–protein boost increased the titer, avidity and persistence of anti-Aβ antibodies in wild-type mice H Davtyan, M Mkrtichyan, N Movsesyan, I Petrushina, G Mamikonyan, ... Gene therapy 17 (2), 261-271, 2010 | 62 | 2010 |
| Absence of microglia promotes diverse pathologies and early lethality in Alzheimer’s disease mice SK Shabestari, S Morabito, EP Danhash, A McQuade, JR Sanchez, ... Cell reports 39 (11), 2022 | 61 | 2022 |
| Differential pulse voltammetric studies of ethidium bromide binding to DNA SH Minasyan, LA Tavadyan, AP Antonyan, HG Davtyan, MA Parsadanyan, ... Bioelectrochemistry 68 (1), 48-55, 2006 | 61 | 2006 |
| Humanized monoclonal antibody armanezumab specific to N-terminus of pathological tau: characterization and therapeutic potency MG Agadjanyan, K Zagorski, I Petrushina, H Davtyan, K Kazarian, ... Molecular neurodegeneration 12, 1-18, 2017 | 56 | 2017 |
| Targeting TLR-4 with a novel pharmaceutical grade plant derived agonist, Immunomax®, as a therapeutic strategy for metastatic breast cancer A Ghochikyan, A Pichugin, A Bagaev, A Davtyan, A Hovakimyan, ... Journal of Translational Medicine 12, 1-12, 2014 | 56 | 2014 |
| Immunogenicity of epitope vaccines targeting different B cell antigenic determinants of human α-synuclein: Feasibility study A Ghochikyan, I Petrushina, H Davtyan, A Hovakimyan, T Saing, ... Neuroscience letters 560, 86-91, 2014 | 55 | 2014 |
