Suivre
Donald Poirier
Donald Poirier
Université Laval and CHU de Québec
Adresse e-mail validée de crchul.ulaval.ca
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Chemopreventive and adjuvant therapeutic potential of pomegranate (Punica granatum) for human breast cancer
ND Kim, R Mehta, W Yu, I Neeman, T Livney, A Amichay, D Poirier, ...
Breast cancer research and treatment 71 (3), 203-217, 2002
7312002
Inhibitors of 17β-hydroxysteroid dehydrogenases
D Poirier
Current medicinal chemistry 10 (6), 453-477, 2003
2602003
Comparison between hippocampus-synthesized and circulation-derived sex steroids in the hippocampus
Y Hojo, S Higo, H Ishii, Y Ooishi, H Mukai, G Murakami, T Kominami, ...
Endocrinology 150 (11), 5106-5112, 2009
1812009
Characteristics of human types 1, 2 and 3 17β-hydroxysteroid dehydrogenase activities: oxidation/reduction and inhibition
V Luu-The, Y Zhang, D Poirier, F Labrie
The Journal of steroid biochemistry and molecular biology 55 (5), 581-587, 1995
1771995
Metal-based biologically active agents: Synthesis, characterization, antibacterial and antileukemia activity evaluation of Cu (II), V (IV) and Ni (II) complexes with antipyrine …
T Rosu, M Negoiu, S Pasculescu, E Pahontu, D Poirier, A Gulea
European journal of medicinal chemistry 45 (2), 774-781, 2010
1762010
Synthesis and characterization of some new Cu (II), Ni (II) and Zn (II) complexes with salicylidene thiosemicarbazones: antibacterial, antifungal and in vitro antileukemia activity
E Pahontu, V Fala, A Gulea, D Poirier, V Tapcov, T Rosu
Molecules 18 (8), 8812-8836, 2013
1542013
Molecular therapy of breast cancer: progress and future directions
SX Lin, J Chen, M Mazumdar, D Poirier, C Wang, A Azzi, M Zhou
Nature Reviews Endocrinology 6 (9), 485-493, 2010
1522010
17β-Hydroxysteroid dehydrogenase inhibitors: a patent review
D Poirier
Expert opinion on therapeutic patents 20 (9), 1123-1145, 2010
1222010
A concerted, rational design of type 1 17β-hydroxysteroid dehydrogenase inhibitors: estradiol-adenosine hybrids with high affinity
W Qiu, RL Campbell, A Gangloff, P Dupuis, RP Boivin, MR Tremblay, ...
The FASEB Journal 16 (13), 1829-1831, 2002
1142002
Structure− Activity Relationships of 17α-Derivatives of Estradiol as Inhibitors of Steroid Sulfatase
RP Boivin, V Luu-The, R Lachance, F Labrie, D Poirier
Journal of medicinal chemistry 43 (23), 4465-4478, 2000
1022000
Overview of a rational approach to design type I 17β-hydroxysteroid dehydrogenase inhibitors without estrogenic activity: chemical synthesis and biological …
MR Tremblay, D Poirier
The Journal of steroid biochemistry and molecular biology 66 (4), 179-191, 1998
1021998
In vitro antileukemia, antibacterial and antifungal activities of some 3d metal complexes: Chemical synthesis and structure – activity relationships
A Gulea, D Poirier, J Roy, V Stavila, I Bulimestru, V Tapcov, M Birca, ...
Journal of enzyme inhibition and medicinal chemistry 23 (6), 806-818, 2008
1012008
17β-hydroxysteroid dehydrogenase Type 1 stimulates breast cancer by dihydrotestosterone inactivation in addition to estradiol production
JA Aka, M Mazumdar, CQ Chen, D Poirier, SX Lin
Molecular endocrinology 24 (4), 832-845, 2010
1002010
Estradiol and estrone C-16 derivatives as inhibitors of type 1 17β-hydroxysteroid dehydrogenase: Blocking of ER+ breast cancer cell proliferation induced by estrone
Y Laplante, C Cadot, MA Fournier, D Poirier
Bioorganic & medicinal chemistry 16 (4), 1849-1860, 2008
982008
Antiestrogenic properties of keoxifene,trans-4-hydroxytamoxifen, and ICI 164384, a new steroidal antiestrogen, in ZR-75-1 human breast cancer cells
R Poulin, Y Merand, D Poirier, C Levesque, JM Dufour, F Labrie
Breast cancer research and treatment 14 (1), 65-76, 1989
981989
Androgen and glucocorticoid receptor-mediated inhibition of cell proliferation by medroxyprogesterone acetate in ZR-75-1 human breast cancer cells
R Poulin, D Baker, D Poirier, F Labrie
Breast cancer research and treatment 13 (2), 161-172, 1989
971989
Binary and ternary crystal structure analyses of a novel inhibitor with 17β-HSD type 1: a lead compound for breast cancer therapy
M Mazumdar, D Fournier, DW Zhu, C Cadot, D Poirier, SX Lin
Biochemical Journal 424 (3), 357-366, 2009
932009
Blockade of the stimulatory effect of estrogens, OH-tamoxifen, OH-toremifene, droloxifene, and raloxifene on alkaline phosphatase activity by the antiestrogen EM-800 in human …
J Simard, R Sanchez, D Poirier, S Gauthier, SM Singh, Y Merand, ...
Cancer research 57 (16), 3494-3497, 1997
931997
Steroid sulfatase inhibitors: a review covering the promising 2000–2010 decade
R Maltais, D Poirier
Steroids 76 (10), 929-948, 2011
902011
Multiple actions of synthetic ‘progestins’ on the growth of ZR-75-1 human breast cancer cells: Anin vitro model for the simultaneous assay of androgen, progestin …
R Poulin, D Baker, D Poirier, F Labrie
Breast cancer research and treatment 17 (3), 197-210, 1991
891991
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