The ‘Digital Twin’to enable the vision of precision cardiology J Corral-Acero, F Margara, M Marciniak, C Rodero, F Loncaric, Y Feng, ... European heart journal 41 (48), 4556-4564, 2020 | 550 | 2020 |
Experimentally calibrated population of models predicts and explains intersubject variability in cardiac cellular electrophysiology OJ Britton, A Bueno-Orovio, K Van Ammel, HR Lu, R Towart, DJ Gallacher, ... Proceedings of the National Academy of Sciences 110 (23), E2098-E2105, 2013 | 356 | 2013 |
Chaste: a test-driven approach to software development for biological modelling J Pitt-Francis, P Pathmanathan, MO Bernabeu, R Bordas, J Cooper, ... Computer Physics Communications 180 (12), 2452-2471, 2009 | 309 | 2009 |
Human In Silico Drug Trials Demonstrate Higher Accuracy than Animal Models in Predicting Clinical Pro-Arrhythmic Cardiotoxicity E Passini, OJ Britton, HR Lu, J Rohrbacher, AN Hermans, DJ Gallacher, ... Frontiers in physiology 8, 668, 2017 | 300 | 2017 |
Computational techniques for ECG analysis and interpretation in light of their contribution to medical advances A Lyon, A Mincholé, JP Martínez, P Laguna, B Rodriguez Journal of The Royal Society Interface 15 (138), 20170821, 2018 | 247 | 2018 |
Fractional diffusion models of cardiac electrical propagation: role of structural heterogeneity in dispersion of repolarization A Bueno-Orovio, D Kay, V Grau, B Rodriguez, K Burrage Journal of The Royal Society Interface 11 (97), 20140352, 2014 | 243 | 2014 |
In silico trials: Verification, validation and uncertainty quantification of predictive models used in the regulatory evaluation of biomedical products M Viceconti, F Pappalardo, B Rodriguez, M Horner, J Bischoff, ... Methods 185, 120-127, 2021 | 230 | 2021 |
Generation of histo-anatomically representative models of the individual heart: tools and application G Plank, RAB Burton, P Hales, M Bishop, T Mansoori, MO Bernabeu, ... Philosophical Transactions of the Royal Society A: Mathematical, Physical …, 2009 | 208 | 2009 |
Development, calibration, and validation of a novel human ventricular myocyte model in health, disease, and drug block J Tomek, A Bueno-Orovio, E Passini, X Zhou, A Minchole, O Britton, ... Elife 8, e48890, 2019 | 191 | 2019 |
Variability in cardiac electrophysiology: using experimentally-calibrated populations of models to move beyond the single virtual physiological human paradigm A Muszkiewicz, OJ Britton, P Gemmell, E Passini, C Sánchez, X Zhou, ... Progress in biophysics and molecular biology 120 (1-3), 115-127, 2016 | 189 | 2016 |
Cardiac transmembrane ion channels and action potentials: cellular physiology and arrhythmogenic behavior V András, J Tomek, N Nagy, L Virág, E Passini, B Rodriguez, I Baczkó Physiological reviews, 2021 | 177 | 2021 |
Differences between left and right ventricular chamber geometry affect cardiac vulnerability to electric shocks B Rodriguez, L Li, JC Eason, IR Efimov, NA Trayanova Circulation research 97 (2), 168-175, 2005 | 160 | 2005 |
Modeling cardiac ischemia B Rodriguez, N Trayanova, D Noble Annals of the New York academy of sciences 1080 (1), 395-414, 2006 | 159 | 2006 |
Machine learning in the electrocardiogram A Mincholé, J Camps, A Lyon, B Rodríguez Journal of electrocardiology 57, S61-S64, 2019 | 155 | 2019 |
δ‐cells and β‐cells are electrically coupled and regulate α‐cell activity via somatostatin LJB Briant, TM Reinbothe, I Spiliotis, C Miranda, B Rodriguez, P Rorsman The Journal of physiology 596 (2), 197-215, 2018 | 153 | 2018 |
Artificial intelligence for the electrocardiogram A Mincholé, B Rodriguez Nature medicine 25 (1), 22-23, 2019 | 150 | 2019 |
Multiscale modelling of drug-induced effects on cardiac electrophysiological activity T Brennan, M Fink, B Rodriguez European Journal of Pharmaceutical Sciences 36 (1), 62-77, 2009 | 146 | 2009 |
Impact of ionic current variability on human ventricular cellular electrophysiology L Romero, E Pueyo, M Fink, B Rodríguez American Journal of Physiology-Heart and Circulatory Physiology 297 (4 …, 2009 | 145 | 2009 |
Mechanisms of pro-arrhythmic abnormalities in ventricular repolarisation and anti-arrhythmic therapies in human hypertrophic cardiomyopathy E Passini, A Mincholé, R Coppini, E Cerbai, B Rodriguez, S Severi, ... Journal of molecular and cellular cardiology 96, 72-81, 2016 | 139 | 2016 |
A multiscale investigation of repolarization variability and its role in cardiac arrhythmogenesis E Pueyo, A Corrias, L Virág, N Jost, T Szél, A Varró, N Szentandrássy, ... Biophysical journal 101 (12), 2892-2902, 2011 | 139 | 2011 |