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Jeroen Frijhoff
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Clinical relevance of biomarkers of oxidative stress
J Frijhoff, PG Winyard, N Zarkovic, SS Davies, R Stocker, D Cheng, ...
Antioxidants & redox signaling 23 (14), 1144-1170, 2015
8552015
Regulation of protein tyrosine phosphatases by reversible oxidation
A Östman, J Frijhoff, Å Sandin, FD Böhmer
The journal of biochemistry 150 (4), 345-356, 2011
3352011
Cancer-associated fibroblasts expressing CXCL14 rely upon NOS1-derived nitric oxide signaling for their tumor-supporting properties
M Augsten, E Sjöberg, O Frings, SU Vorrink, J Frijhoff, E Olsson, Å Borg, ...
Cancer research 74 (11), 2999-3010, 2014
1402014
12/15-lipoxygenase–derived lipid peroxides control receptor tyrosine kinase signaling through oxidation of protein tyrosine phosphatases
M Conrad, Å Sandin, H Förster, A Seiler, J Frijhoff, M Dagnell, ...
Proceedings of the National Academy of Sciences 107 (36), 15774-15779, 2010
1072010
Selective activation of oxidized PTP1B by the thioredoxin system modulates PDGF-β receptor tyrosine kinase signaling
M Dagnell, J Frijhoff, I Pader, M Augsten, B Boivin, J Xu, PK Mandal, ...
Proceedings of the National Academy of Sciences 110 (33), 13398-13403, 2013
1042013
Glioma-induced inhibition of caspase-3 in microglia promotes a tumor-supportive phenotype
X Shen, MA Burguillos, AM Osman, J Frijhoff, A Carrillo-Jimenez, ...
Nature immunology 17 (11), 1282-1290, 2016
932016
Differential up-regulation of MAP kinase phosphatases MKP3/DUSP6 and DUSP5 by Ets2 and c-Jun converge in the control of the growth arrest versus proliferation response of MCF-7 …
CE Nunes-Xavier, C Tarrega, R Cejudo-Marin, J Frijhoff, Å Sandin, ...
Journal of biological chemistry 285 (34), 26417-26430, 2010
672010
Regulation of protein tyrosine phosphatase oxidation in cell adhesion and migration
J Frijhoff, M Dagnell, R Godfrey, A Östman
Antioxidants & redox signaling 20 (13), 1994-2010, 2014
652014
Knockout of mitochondrial thioredoxin reductase stabilizes prolyl hydroxylase 2 and inhibits tumor growth and tumor-derived angiogenesis
J Hellfritsch, J Kirsch, M Schneider, T Fluege, M Wortmann, J Frijhoff, ...
Antioxidants & redox signaling 22 (11), 938-950, 2015
542015
The mitochondrial reactive oxygen species regulator p66Shc controls PDGF-induced signaling and migration through protein tyrosine phosphatase oxidation
J Frijhoff, M Dagnell, M Augsten, E Beltrami, M Giorgio, A Östman
Free Radical Biology and Medicine 68, 268-277, 2014
532014
Thioredoxin reductase 1 and NADPH directly protect protein tyrosine phosphatase 1B from inactivation during H2O2 exposure
M Dagnell, PE Pace, Q Cheng, J Frijhoff, A Östman, ESJ Arnér, ...
Journal of Biological Chemistry 292 (35), 14371-14380, 2017
402017
Clinical relevance of cyclic GMP modulators: a translational success story of network pharmacology
JM Oettrich, VT Dao, J Frijhoff, PWM Kleikers, AI Casas, AJ Hobbs, ...
Clinical Pharmacology & Therapeutics 99 (4), 360-362, 2016
182016
Effects of epigenetic modificators in combination with small molecule inhibitors of receptor tyrosine kinases on medulloblastoma growth
AM Marino, J Frijhoff, R Calero, N Baryawno, A Östman, JI Johnsen
Biochemical and Biophysical Research Communications 450 (4), 1600-1605, 2014
122014
Protein nitration is a physiological regulator of cardiac lactate dehydrogenase active site loop mobility and activity
C Nogales, J Frijhoff, D Thoenges, RB Sessions, A Sickmann, ...
bioRxiv, 348789, 2018
32018
Thioredoxin Reductase 1 Directly Protects Protein Tyrosine Phosphatase 1B from Inactivation by H2O2
M Dagnell, P Pace, Q Cheng, J Frijhoff, A Östman, E Arnér, M Hampton, ...
Free Radical Biology and Medicine 100, S47, 2016
2016
MECHANISMS UNDERLYING THE PRO-TUMORIGENIC EFFECT OF CXCL14-EXPRESSING CANCER-ASSOCIATED FIBROBLASTS
M Augsten, E Sjoberg, O Frings, J Frijhoff, A Ostman
ANTICANCER RESEARCH 34 (10), 5821-5822, 2014
2014
Protein Tyrosine Phosphatases: Taking a'redoxionist'Look at PDGFR Signaling
J Frijhoff
PQDT-Global, 2014
2014
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Articles 1–17