GDF15 provides an endocrine signal of nutritional stress in mice and humans S Patel, A Alvarez-Guaita, A Melvin, D Rimmington, A Dattilo, ... Cell metabolism 29 (3), 707-718. e8, 2019 | 335 | 2019 |
Stimulation of muscle cell glucose uptake by resveratrol through sirtuins and AMPK DM Breen, T Sanli, A Giacca, E Tsiani Biochemical and biophysical research communications 374 (1), 117-122, 2008 | 269 | 2008 |
Jejunal nutrient sensing is required for duodenal-jejunal bypass surgery to rapidly lower glucose concentrations in uncontrolled diabetes DM Breen, BA Rasmussen, A Kokorovic, R Wang, GWC Cheung, ... Nature medicine 18 (6), 950-955, 2012 | 252 | 2012 |
Resveratrol activates duodenal Sirt1 to reverse insulin resistance in rats through a neuronal network CD Côté, BA Rasmussen, FA Duca, M Zadeh-Tahmasebi, JA Baur, ... Nature medicine 21 (5), 498-505, 2015 | 152 | 2015 |
Latest approaches for the treatment of obesity VM Jackson, DM Breen, JP Fortin, A Liou, JB Kuzmiski, AK Loomis, ... Expert opinion on drug discovery 10 (8), 825-839, 2015 | 123 | 2015 |
GDF-15 neutralization alleviates platinum-based chemotherapy-induced emesis, anorexia, and weight loss in mice and nonhuman primates DM Breen, H Kim, D Bennett, RA Calle, S Collins, RM Esquejo, T He, ... Cell metabolism 32 (6), 938-950. e6, 2020 | 80 | 2020 |
Nutrient-sensing mechanisms in the gut as therapeutic targets for diabetes DM Breen, BA Rasmussen, CD Côté, VM Jackson, TKT Lam Diabetes 62 (9), 3005-3013, 2013 | 76 | 2013 |
Insulin increases reendothelialization and inhibits cell migration and neointimal growth after arterial injury DM Breen, KK Chan, JK Dhaliwall, MR Ward, N Al Koudsi, L Lam, ... Arteriosclerosis, thrombosis, and vascular biology 29 (7), 1060-1066, 2009 | 73 | 2009 |
GDF15 induces an aversive visceral malaise state that drives anorexia and weight loss T Borner, HS Wald, MY Ghidewon, B Zhang, Z Wu, BC De Jonghe, ... Cell Reports 31 (3), 2020 | 61 | 2020 |
Resveratrol inhibits neointimal formation after arterial injury through an endothelial nitric oxide synthase-dependent mechanism DM Breen, VW Dolinsky, H Zhang, H Ghanim, J Guo, M Mroziewicz, ... Atherosclerosis 222 (2), 375-381, 2012 | 60 | 2012 |
Duodenal activation of cAMP-dependent protein kinase induces vagal afferent firing and lowers glucose production in rats BA Rasmussen, DM Breen, P Luo, GWC Cheung, CS Yang, B Sun, ... Gastroenterology 142 (4), 834-843. e3, 2012 | 58 | 2012 |
Lipid sensing in the gut, brain and liver BA Rasmussen, DM Breen, TKT Lam Trends in Endocrinology & Metabolism 23 (2), 49-55, 2012 | 54 | 2012 |
Activation of the hypothalamic–pituitary–adrenal axis by exogenous and endogenous GDF15 I Cimino, H Kim, YCL Tung, K Pedersen, D Rimmington, JA Tadross, ... Proceedings of the National Academy of Sciences 118 (27), e2106868118, 2021 | 47 | 2021 |
Resveratrol prevents insulin resistance caused by short-term elevation of free fatty acids in vivo S Pereira, E Park, J Moore, B Faubert, DM Breen, AI Oprescu, A Nahle, ... Applied Physiology, Nutrition, and Metabolism 40 (11), 1129-1136, 2015 | 40 | 2015 |
Duodenal PKC-δ and cholecystokinin signaling axis regulates glucose production DM Breen, JTY Yue, BA Rasmussen, A Kokorovic, GWC Cheung, ... Diabetes 60 (12), 3148-3153, 2011 | 40 | 2011 |
Duodenal mucosal protein kinase C-δ regulates glucose production in rats A Kokorovic, GWC Cheung, DM Breen, M Chari, CKL Lam, TKT Lam Gastroenterology 141 (5), 1720-1727, 2011 | 37 | 2011 |
Jejunal leptin-PI3K signaling lowers glucose production BA Rasmussen, DM Breen, FA Duca, CD Côté, M Zadeh-Tahmasebi, ... Cell Metabolism 19 (1), 155-161, 2014 | 35 | 2014 |
Gut–brain signalling: how lipids can trigger the gut DM Breen, CS Yang, TKT Lam Diabetes/metabolism research and reviews 27 (2), 113-119, 2011 | 31 | 2011 |
In vivo effects of polyunsaturated, monounsaturated, and saturated fatty acids on hepatic and peripheral insulin sensitivity S Pereira, DM Breen, AE Naassan, PYT Wang, H Uchino, IG Fantus, ... Metabolism 64 (2), 315-322, 2015 | 28 | 2015 |
The effect of insulin to decrease neointimal growth after arterial injury is endothelial nitric oxide synthase-dependent J Guo, DM Breen, TJ Pereira, PS Dalvi, H Zhang, Y Mori, H Ghanim, ... Atherosclerosis 241 (1), 111-120, 2015 | 22 | 2015 |