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Danna M Breen
Danna M Breen
Principle Scientist, Pfizer Inc
Verified email at pfizer.com
Title
Cited by
Cited by
Year
GDF15 provides an endocrine signal of nutritional stress in mice and humans
S Patel, A Alvarez-Guaita, A Melvin, D Rimmington, A Dattilo, ...
Cell metabolism 29 (3), 707-718. e8, 2019
3352019
Stimulation of muscle cell glucose uptake by resveratrol through sirtuins and AMPK
DM Breen, T Sanli, A Giacca, E Tsiani
Biochemical and biophysical research communications 374 (1), 117-122, 2008
2692008
Jejunal nutrient sensing is required for duodenal-jejunal bypass surgery to rapidly lower glucose concentrations in uncontrolled diabetes
DM Breen, BA Rasmussen, A Kokorovic, R Wang, GWC Cheung, ...
Nature medicine 18 (6), 950-955, 2012
2522012
Resveratrol activates duodenal Sirt1 to reverse insulin resistance in rats through a neuronal network
CD Côté, BA Rasmussen, FA Duca, M Zadeh-Tahmasebi, JA Baur, ...
Nature medicine 21 (5), 498-505, 2015
1522015
Latest approaches for the treatment of obesity
VM Jackson, DM Breen, JP Fortin, A Liou, JB Kuzmiski, AK Loomis, ...
Expert opinion on drug discovery 10 (8), 825-839, 2015
1232015
GDF-15 neutralization alleviates platinum-based chemotherapy-induced emesis, anorexia, and weight loss in mice and nonhuman primates
DM Breen, H Kim, D Bennett, RA Calle, S Collins, RM Esquejo, T He, ...
Cell metabolism 32 (6), 938-950. e6, 2020
802020
Nutrient-sensing mechanisms in the gut as therapeutic targets for diabetes
DM Breen, BA Rasmussen, CD Côté, VM Jackson, TKT Lam
Diabetes 62 (9), 3005-3013, 2013
762013
Insulin increases reendothelialization and inhibits cell migration and neointimal growth after arterial injury
DM Breen, KK Chan, JK Dhaliwall, MR Ward, N Al Koudsi, L Lam, ...
Arteriosclerosis, thrombosis, and vascular biology 29 (7), 1060-1066, 2009
732009
GDF15 induces an aversive visceral malaise state that drives anorexia and weight loss
T Borner, HS Wald, MY Ghidewon, B Zhang, Z Wu, BC De Jonghe, ...
Cell Reports 31 (3), 2020
612020
Resveratrol inhibits neointimal formation after arterial injury through an endothelial nitric oxide synthase-dependent mechanism
DM Breen, VW Dolinsky, H Zhang, H Ghanim, J Guo, M Mroziewicz, ...
Atherosclerosis 222 (2), 375-381, 2012
602012
Duodenal activation of cAMP-dependent protein kinase induces vagal afferent firing and lowers glucose production in rats
BA Rasmussen, DM Breen, P Luo, GWC Cheung, CS Yang, B Sun, ...
Gastroenterology 142 (4), 834-843. e3, 2012
582012
Lipid sensing in the gut, brain and liver
BA Rasmussen, DM Breen, TKT Lam
Trends in Endocrinology & Metabolism 23 (2), 49-55, 2012
542012
Activation of the hypothalamic–pituitary–adrenal axis by exogenous and endogenous GDF15
I Cimino, H Kim, YCL Tung, K Pedersen, D Rimmington, JA Tadross, ...
Proceedings of the National Academy of Sciences 118 (27), e2106868118, 2021
472021
Resveratrol prevents insulin resistance caused by short-term elevation of free fatty acids in vivo
S Pereira, E Park, J Moore, B Faubert, DM Breen, AI Oprescu, A Nahle, ...
Applied Physiology, Nutrition, and Metabolism 40 (11), 1129-1136, 2015
402015
Duodenal PKC-δ and cholecystokinin signaling axis regulates glucose production
DM Breen, JTY Yue, BA Rasmussen, A Kokorovic, GWC Cheung, ...
Diabetes 60 (12), 3148-3153, 2011
402011
Duodenal mucosal protein kinase C-δ regulates glucose production in rats
A Kokorovic, GWC Cheung, DM Breen, M Chari, CKL Lam, TKT Lam
Gastroenterology 141 (5), 1720-1727, 2011
372011
Jejunal leptin-PI3K signaling lowers glucose production
BA Rasmussen, DM Breen, FA Duca, CD Côté, M Zadeh-Tahmasebi, ...
Cell Metabolism 19 (1), 155-161, 2014
352014
Gut–brain signalling: how lipids can trigger the gut
DM Breen, CS Yang, TKT Lam
Diabetes/metabolism research and reviews 27 (2), 113-119, 2011
312011
In vivo effects of polyunsaturated, monounsaturated, and saturated fatty acids on hepatic and peripheral insulin sensitivity
S Pereira, DM Breen, AE Naassan, PYT Wang, H Uchino, IG Fantus, ...
Metabolism 64 (2), 315-322, 2015
282015
The effect of insulin to decrease neointimal growth after arterial injury is endothelial nitric oxide synthase-dependent
J Guo, DM Breen, TJ Pereira, PS Dalvi, H Zhang, Y Mori, H Ghanim, ...
Atherosclerosis 241 (1), 111-120, 2015
222015
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