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Grace O Silva
Grace O Silva
UNC Lineberger Comprehensive Cancer Center
Verified email at tesseratx.com
Title
Cited by
Cited by
Year
Comprehensive molecular portraits of human breast tumours
Brigham & Women’s Hospital & Harvard Medical School Chin Lynda 9 11 Park ...
Nature 490 (7418), 61-70, 2012
110222012
Progesterone receptor modulates ERα action in breast cancer
H Mohammed, IA Russell, R Stark, OM Rueda, TE Hickey, GA Tarulli, ...
Nature 523 (7560), 313-317, 2015
7292015
An integrated genomics approach identifies drivers of proliferation in luminal-subtype human breast cancer
ML Gatza, GO Silva, JS Parker, C Fan, CM Perou
Nature genetics 46 (10), 1051-1059, 2014
2822014
Comprehensive analysis of The Cancer Genome Atlas reveals a unique gene and non-coding RNA signature of fibrolamellar carcinoma
TA Dinh, ECM Vitucci, E Wauthier, RP Graham, WA Pitman, T Oikawa, ...
Scientific reports 7 (1), 44653, 2017
842017
Loss of Heterozygosity at the CYP2D6 Locus in Breast Cancer: Implications for Germline Pharmacogenetic Studies
MP Goetz, JX Sun, VJ Suman, GO Silva, CM Perou, Y Nakamura, NJ Cox, ...
Journal of the National Cancer Institute 107 (2), dju401, 2015
682015
Amplification of SOX4 promotes PI3K/Akt signaling in human breast cancer
GA Mehta, JS Parker, GO Silva, KA Hoadley, CM Perou, ML Gatza
Breast cancer research and treatment 162, 439-450, 2017
542017
Cross-species DNA copy number analyses identifies multiple 1q21-q23 subtype-specific driver genes for breast cancer
GO Silva, X He, JS Parker, ML Gatza, LA Carey, JP Hou, SL Moulder, ...
Breast cancer research and treatment 152, 347-356, 2015
492015
Activating PIK3CA mutations induce an epidermal growth factor receptor (EGFR)/extracellular signal-regulated kinase (ERK) paracrine signaling axis in basal-like breast cancer
CD Young, LJ Zimmerman, D Hoshino, L Formisano, AB Hanker, ...
Molecular & cellular proteomics 14 (7), 1959-1976, 2015
392015
SynthEx: a synthetic-normal-based DNA sequencing tool for copy number alteration detection and tumor heterogeneity profiling
GO Silva, MB Siegel, LE Mose, JS Parker, W Sun, CM Perou, M Chen
Genome biology 18, 1-14, 2017
262017
A mouse model featuring tissue-specific deletion of p53 and Brca1 gives rise to mammary tumors with genomic and transcriptomic similarities to human basal-like breast cancer
DP Hollern, CM Contreras, S Dance-Barnes, GO Silva, AD Pfefferle, ...
Breast cancer research and treatment 174, 143-155, 2019
222019
Characterization of copy number alterations in a mouse model of fibrosis‐associated hepatocellular carcinoma reveals concordance with human disease
G Chappell, GO Silva, T Uehara, IP Pogribny, I Rusyn
Cancer Medicine 5 (3), 574-585, 2016
82016
Activating PIK3CA mutations induce an EGFR/ERK paracrine signaling axis in basal-like breast cancer
CD Young, LJ Zimmerman, D Hoshino, L Formisano, AB Hanker, ...
Mol Cell Proteomics 14, 1959-1976, 2015
72015
Development of a selective CDK2-E inhibitor in CCNE driven cancers
YJ Choi, S Wenglowsky, V Brown, N Bifulco, YS Choi, J Guo, M Hatlen, ...
Cancer research 81 (13_Supplement), 1279-1279, 2021
62021
MAP4K1 inhibition enhances immune cell activation and anti-tumor immunity in preclinical tumor models
K Faia, A Toso, K Fetalvero, M Roche, S Bench, E O'Hearn, Q Cao, ...
Cancer Research 81 (13_Supplement), 1717-1717, 2021
52021
Evaluation of PRKACA as a therapeutic target for fibrolamellar carcinoma
SS Schalm, E O’Hearn, K Wilson, TP LaBranche, G Silva, Z Zhang, ...
bioRxiv, 2022.01. 31.477690, 2022
42022
combination therapy with MEK inhibition is efficacious in intracranial triple negative breast cancer models
AED Van Swearingen, MB Siegel, MJ Sambade, S Sud, SM Miller, G Silva, ...
Cancer Research 75 (15_Supplement), 2579-2579, 2015
12015
Evaluation of Protein Kinase cAMP-Activated Catalytic Subunit Alpha as a Therapeutic Target for Fibrolamellar Carcinoma
SS Schalm, E O’Hearn, K Wilson, TP LaBranche, G Silva, Z Zhang, ...
Gastro Hep Advances 2 (3), 307-321, 2023
2023
Abstract B127: Evaluating PRKACA as a therapeutic target for Fibrolamellar Carcinoma
SS Schalm, E O’Hearn, K Wilson, T LaBranche, G Silva, L DiPietro, ...
Molecular Cancer Therapeutics 18 (12_Supplement), B127-B127, 2019
2019
Abstract S4-01: Identification of early versus late drivers of breast tumors and metastasis
MB Siegel, X He, M Chen, JP Hou, AL Garrett, JB Dye, GO Silva, JE Usary, ...
Cancer Research 76 (4_Supplement), S4-01-S4-01, 2016
2016
Targeted agents and chemotherapeutic treatments of genetically engineered Basal-like breast cancer mouse model
CM Contreras, GO Silva, AD Pfefferle, CM Perou
Cancer Research 75 (15_Supplement), 2307-2307, 2015
2015
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