AAV-expressed eCD4-Ig provides durable protection from multiple SHIV challenges MR Gardner, LM Kattenhorn, HR Kondur, M Von Schaewen, T Dorfman, ... Nature 519 (7541), 87-91, 2015 | 339 | 2015 |
CD26, adenosine deaminase, and adenosine receptors mediate costimulatory signals in the immunological synapse R Pacheco, JM Martinez-Navio, M Lejeune, N Climent, H Oliva, JM Gatell, ... Proceedings of the National Academy of Sciences 102 (27), 9583-9588, 2005 | 310 | 2005 |
Glutamate released by dendritic cells as a novel modulator of T cell activation R Pacheco, H Oliva, JM Martinez-Navío, N Climent, F Ciruela, JM Gatell, ... The Journal of Immunology 177 (10), 6695-6704, 2006 | 182 | 2006 |
Adeno-associated virus delivery of anti-HIV monoclonal antibodies can drive long-term virologic suppression JM Martinez-Navio, SP Fuchs, SN Pantry, WA Lauer, NN Duggan, ... Immunity 50 (3), 567-575. e5, 2019 | 112 | 2019 |
AAV-delivered antibody mediates significant protective effects against SIVmac239 challenge in the absence of neutralizing activity SP Fuchs, JM Martinez-Navio, M Piatak Jr, JD Lifson, G Gao, ... PLoS pathogens 11 (8), e1005090, 2015 | 105 | 2015 |
Adenosine deaminase potentiates the generation of effector, memory, and regulatory CD4+ T cells JM Martinez‐Navio, V Casanova, R Pacheco, I Naval‐Macabuhay, ... Journal of Leukocyte Biology 89 (1), 127-136, 2011 | 78 | 2011 |
Host anti-antibody responses following adeno-associated virus–mediated delivery of antibodies against HIV and SIV in rhesus monkeys JM Martinez-Navio, SP Fuchs, S Pedreño-López, EG Rakasz, G Gao, ... Molecular Therapy 24 (1), 76-86, 2016 | 74 | 2016 |
Anti-drug antibody responses impair prophylaxis mediated by AAV-delivered HIV-1 broadly neutralizing antibodies MR Gardner, I Fetzer, LM Kattenhorn, ME Davis-Gardner, AS Zhou, ... Molecular Therapy 27 (3), 650-660, 2019 | 59 | 2019 |
Long-term delivery of an anti-SIV monoclonal antibody with AAV JM Martinez-Navio, SP Fuchs, DE Mendes, EG Rakasz, G Gao, JD Lifson, ... Frontiers in immunology 11, 449, 2020 | 41 | 2020 |
Immunological dysfunction in HIV‐1‐infected individuals caused by impairment of adenosine deaminase‐induced costimulation of T‐cell activation JM Martinez‐Navio, N Climent, R Pacheco, F Garcia, M Plana, ... Immunology 128 (3), 393-404, 2009 | 40 | 2009 |
Adenosine deaminase enhances T‐cell response elicited by dendritic cells loaded with inactivated HIV N Climent, JM Martinez‐Navio, C Gil, F Garcia, C Rovira, C Hurtado, ... Immunology and cell biology 87 (8), 634-639, 2009 | 30 | 2009 |
Recombinant AAV vectors for enhanced expression of authentic IgG SP Fuchs, JM Martinez-Navio, G Gao, RC Desrosiers PLoS One 11 (6), e0158009, 2016 | 28 | 2016 |
Potent plasmablast-derived antibodies elicited by the National Institutes of Health dengue vaccine DM Magnani, CGT Silveira, MJ Ricciardi, L Gonzalez-Nieto, ... Journal of virology 91 (22), e00867-17, 2017 | 27 | 2017 |
Liver-directed but not muscle-directed AAV-antibody gene transfer limits humoral immune responses in rhesus monkeys SP Fuchs, JM Martinez-Navio, EG Rakasz, G Gao, RC Desrosiers Molecular Therapy-Methods & Clinical Development 16, 94-102, 2020 | 25 | 2020 |
Adenosine deaminase regulates Treg expression in autologous T cell-dendritic cell cocultures from patients infected with HIV-1 I Naval-Macabuhay, V Casanova, G Navarro, F García, A León, L Miralles, ... Journal of Leucocyte Biology 99 (2), 349-359, 2016 | 24 | 2016 |
Dengue virus evades AAV-mediated neutralizing antibody prophylaxis in rhesus monkeys DM Magnani, MJ Ricciardi, VK Bailey, MJ Gutman, N Pedreño-Lopez, ... Molecular therapy 25 (10), 2323-2331, 2017 | 22 | 2017 |
Evidence against extracellular exposure of a highly immunogenic region in the C-terminal domain of the simian immunodeficiency virus gp41 transmembrane protein TS Postler, JM Martinez-Navio, E Yuste, RC Desrosiers Journal of virology 86 (2), 1145-1157, 2012 | 22 | 2012 |
A human inferred germline antibody binds to an immunodominant epitope and neutralizes Zika virus DM Magnani, CGT Silveira, BC Rosen, MJ Ricciardi, N Pedreño-Lopez, ... PLoS neglected tropical diseases 11 (6), e0005655, 2017 | 20 | 2017 |
High concordance of ELISA and neutralization assays allows for the detection of antibodies to individual AAV serotypes MR Gardner, DE Mendes, CP Muniz, JM Martinez-Navio, SP Fuchs, ... Molecular Therapy-Methods & Clinical Development 24, 199-206, 2022 | 15 | 2022 |
Increased expression with differential subcellular location of cytidine deaminase APOBEC3G in human CD4+ T‐cell activation and dendritic cell maturation H Oliva, R Pacheco, JM Martinez‐Navio, M Rodríguez‐García, ... Immunology and cell biology 94 (7), 689-700, 2016 | 13 | 2016 |