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Daneen Schaeffer, Ph.D.
Daneen Schaeffer, Ph.D.
Postdoctoral Fellow, Janssen
Verified email at ITS.jnj.com
Title
Cited by
Cited by
Year
The exosome contains domains with specific endoribonuclease, exoribonuclease and cytoplasmic mRNA decay activities
D Schaeffer, B Tsanova, A Barbas, FP Reis, EG Dastidar, ...
Nature structural & molecular biology 16 (1), 56-62, 2009
3432009
Cellular migration and invasion uncoupled: increased migration is not an inexorable consequence of epithelial-to-mesenchymal transition
D Schaeffer, JA Somarelli, G Hanna, GM Palmer, MA Garcia-Blanco
Molecular and cellular biology 34 (18), 3486-3499, 2014
1102014
Different nuclease requirements for exosome-mediated degradation of normal and nonstop mRNAs
D Schaeffer, A van Hoof
Proceedings of the National Academy of Sciences 108 (6), 2366-2371, 2011
852011
The role of epithelial plasticity in prostate cancer dissemination and treatment resistance
RL Bitting, D Schaeffer, JA Somarelli, MA Garcia-Blanco, AJ Armstrong
Cancer and Metastasis Reviews 33, 441-468, 2014
772014
Functions of the cytoplasmic exosome
D Schaeffer, A Clark, AA Klauer, B Tsanova, A van Hoof
RNA exosome, 79-90, 2010
592010
The CR3 motif of Rrp44p is important for interaction with the core exosome and exosome function
D Schaeffer, FP Reis, SJ Johnson, CM Arraiano, A Van Hoof
Nucleic acids research 40 (18), 9298-9307, 2012
512012
Distinct routes to metastasis: plasticity-dependent and plasticity-independent pathways
JA Somarelli, D Schaeffer, MS Marengo, T Bepler, D Rouse, KE Ware, ...
Oncogene, 2016
502016
Snail promotes resistance to enzalutamide through regulation of androgen receptor activity in prostate cancer
KE Ware, JA Somarelli, D Schaeffer, J Li, T Zhang, S Park, SR Patierno, ...
Oncotarget 7 (31), 50507, 2016
492016
Fluorescence-based alternative splicing reporters for the study of epithelial plasticity in vivo
JA Somarelli, D Schaeffer, R Bosma, VI Bonano, JW Sohn, G Kemeny, ...
Rna 19 (1), 116-127, 2013
242013
Modulating the RNA processing and decay by the exosome: altering Rrp44/Dis3 activity and end-product
FP Reis, A Barbas, AA Klauer-King, B Tsanova, D Schaeffer, ...
PloS one 8 (11), e76504, 2013
162013
RNase II structure completes group portrait of 3′ exoribonucleases
D Grossman, A van Hoof
Nature structural & molecular biology 13 (9), 760-761, 2006
152006
Determining in vivo activity of the yeast cytoplasmic exosome
D Schaeffer, S Meaux, A Clark, A van Hoof
Methods in enzymology 448, 227-239, 2008
112008
Snail promotes resistance to enzalutamide through regulation of androgen receptor activity in prostate cancer. Oncotarget. 2016; 7: 50507-50521
KE Ware, JA Somarelli, D Schaeffer, J Li, T Zhang, S Park, SR Patierno, ...
4
AR-V7 regulation during epithelial plasticity
KE Ware, D Schaeffer, T Zhang, MA Garcia-Blanco, AJ Armstrong
Cancer Research 75 (15_Supplement), 1847-1847, 2015
12015
Modulating the RNA Processing and Decay by the Exosome: Altering Rrp44/Dis3 Activity and End-Product (vol 8, e76504, 2013)
FP Reis, A Barbas, AA Klauer-King, B Tsanova, D Schaeffer, ...
PLOS ONE 10 (8), 2015
2015
Correction: Modulating the RNA Processing and Decay by the Exosome: Altering Rrp44/Dis3 Activity and End-Product
FP Reis, A Barbas, AA Klauer-King, B Tsanova, D Schaeffer, ...
Plos one 10 (8), e0136810, 2015
2015
Abstract SS02-02: A long walk from FGFR2 alternative splicing to cancer progression
JA Somarelli, JA Somarelli, D Schaeffer, D Schaeffer, MS Marengo, ...
Cancer Epidemiology, Biomarkers & Prevention 23 (11_Supplement), SS02-02-SS02-02, 2014
2014
The Domains of the Catalytic Subunit of the Eukaryotic RNA Degrading Exosome, Rrp44p, have Distinct Functions
D Schaeffer
2010
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Articles 1–18