The mutational landscape of normal human endometrial epithelium L Moore, D Leongamornlert, THH Coorens, MA Sanders, P Ellis, ... Nature 580 (7805), 640-646, 2020 | 418 | 2020 |
Somatic mutation rates scale with lifespan across mammals A Cagan, A Baez-Ortega, N Brzozowska, F Abascal, THH Coorens, ... Nature 604 (7906), 517-524, 2022 | 315 | 2022 |
The mutational landscape of human somatic and germline cells L Moore, A Cagan, THH Coorens, MDC Neville, R Sanghvi, MA Sanders, ... Nature 597 (7876), 381-386, 2021 | 257 | 2021 |
Extensive heterogeneity in somatic mutation and selection in the human bladder ARJ Lawson, F Abascal, THH Coorens, Y Hooks, L O’Neill, C Latimer, ... Science 370 (6512), 75-82, 2020 | 244 | 2020 |
Non-random fragmentation patterns in circulating cell-free DNA reflect epigenetic regulation M Ivanov, A Baranova, T Butler, P Spellman, V Mileyko BMC genomics 16, 1-12, 2015 | 224 | 2015 |
Phylogenetic analyses of melanoma reveal complex patterns of metastatic dissemination JZ Sanborn, J Chung, E Purdom, NJ Wang, H Kakavand, JS Wilmott, ... Proceedings of the National Academy of Sciences 112 (35), 10995-11000, 2015 | 175 | 2015 |
Somatic evolution in non-neoplastic IBD-affected colon S Olafsson, RE McIntyre, T Coorens, T Butler, H Jung, PS Robinson, ... Cell 182 (3), 672-684. e11, 2020 | 153 | 2020 |
Exome sequencing of cell-free DNA from metastatic cancer patients identifies clinically actionable mutations distinct from primary disease TM Butler, K Johnson-Camacho, M Peto, NJ Wang, TA Macey, JE Korkola, ... PloS one 10 (8), e0136407, 2015 | 135 | 2015 |
Assessing copy number alterations in targeted, amplicon-based next-generation sequencing data C Grasso, T Butler, K Rhodes, M Quist, TL Neff, S Moore, SA Tomlins, ... The Journal of Molecular Diagnostics 17 (1), 53-63, 2015 | 133 | 2015 |
Circulating tumor cells in hepatocellular carcinoma: a pilot study of detection, enumeration, and next-generation sequencing in cases and controls RK Kelley, MJM Magbanua, TM Butler, EA Collisson, J Hwang, ... BMC cancer 15, 1-11, 2015 | 129 | 2015 |
Convergent somatic mutations in metabolism genes in chronic liver disease SWK Ng, FJ Rouhani, SF Brunner, N Brzozowska, SJ Aitken, M Yang, ... Nature 598 (7881), 473-478, 2021 | 116 | 2021 |
Lineage tracing of human development through somatic mutations M Spencer Chapman, AM Ranzoni, B Myers, N Williams, THH Coorens, ... Nature 595 (7865), 85-90, 2021 | 116 | 2021 |
Reliable detection of somatic mutations in solid tissues by laser-capture microdissection and low-input DNA sequencing P Ellis, L Moore, MA Sanders, TM Butler, SF Brunner, H Lee-Six, ... Nature Protocols 16 (2), 841-871, 2021 | 103 | 2021 |
Arctic mustard flower color polymorphism controlled by petal-specific downregulation at the threshold of the anthocyanin biosynthetic pathway CA Dick, J Buenrostro, T Butler, ML Carlson, DJ Kliebenstein, JB Whittall PloS one 6 (4), e18230, 2011 | 101 | 2011 |
Circulating-tumor DNA as an early detection and diagnostic tool TM Butler, PT Spellman, J Gray Current opinion in genetics & development 42, 14-21, 2017 | 85 | 2017 |
Mapping single-cell transcriptomes in the intra-tumoral and associated territories of kidney cancer R Li, JR Ferdinand, KW Loudon, GS Bowyer, S Laidlaw, F Muyas, ... Cancer Cell 40 (12), 1583-1599. e10, 2022 | 80 | 2022 |
Transient commensal clonal interactions can drive tumor metastasis S Naffar-Abu Amara, HJ Kuiken, LM Selfors, T Butler, ML Leung, ... Nature communications 11 (1), 5799, 2020 | 38 | 2020 |
Prescribing patterns for asthma by general practitioners in six European countries G Jepson, T Butler, D Gregory, K Jones Respiratory medicine 94 (6), 578-583, 2000 | 38 | 2000 |
Circulating tumor DNA dynamics using patient-customized assays are associated with outcome in neoadjuvantly treated breast cancer TM Butler, CT Boniface, K Johnson-Camacho, S Tabatabaei, D Melendez, ... Molecular Case Studies 5 (2), a003772, 2019 | 37 | 2019 |
Using social network analysis to complete literature reviews: a new systematic approach for independent researchers to detect and interpret prominent research programs within … T Cowhitt, T Butler, E Wilson International Journal of Social Research Methodology 23 (5), 483-496, 2020 | 30 | 2020 |